Antipsikotik atipikal

Apa iku antipsikotik atipikal?

Antipsikotik atipikal yaiku antipsikotik sing luwih cilik tinimbang antipsikotik tradisional nyebabake efek samping tartamtu, kayata gejala ekstrapiramidal (EPS). EPS minangka kelainan gerakan sing disebabake obat-obatan lan kalebu tremor, gejala kaya Parkinson (mlaku kanthi acak, fitur rai kaya topeng) lan tardive dyskinesia (iki nggambarake gerakan rai sing ora normal, bola-bali kayata lip smacking utawa poking ilat metu).< /p>

Aneka antipsikotik atipikal ditemokake bubar; Nanging, clozapine asring diarani minangka antipsikotik atipikal sanajan ditemokake luwih saka 60 taun kepungkur. Antipsikotik atipikal uga dikenal minangka antipsikotik generasi kapindho.

Para ahli ora ngerti persis cara kerja antipsikotik atipikal nanging katon mblokir reseptor kimia tartamtu ing otak, sing mengaruhi tingkat macem-macem neurotransmitter kayata dopamin, asetilkolin, noradrenalin. , utawa serotonin. Antipsikotik atipikal katon duwe afinitas sing luwih dhuwur kanggo reseptor serotonin lan afinitas sing luwih murah kanggo reseptor dopamin tinimbang antipsikotik khas.

Apa sing digunakake antipsikotik atipikal?

Antipsikotik atipikal digunakake kanggo ngilangi gejala. kayata khayalan (kapercayan sing salah), krungu swara, ndeleng barang sing ora ana (halusinasi), utawa pikirane paranoid utawa bingung sing biasane digandhengake karo sawetara penyakit mental.

Bisa digunakake kanggo nambani gejala skizofrenia utawa episode psikotik; ing perawatan saka depresi abot; agitasi abot utawa kuatir; utawa kanggo stabil episode mania ing wong kelainan Bipolar. Sawetara sing disetujoni FDA kanggo bocah-bocah kanggo nambani iritasi sing ana gandhengane karo kelainan Autistik.

Apa bedane antarane antipsikotik atipikal?

Atipsikotik atipikal beda-beda ing cara diserap menyang awak. , carane padha dimetabolisme, dawa efeke, lan carane diekskresi. Ana uga beda-beda ing antarane:

Tambahan bobot: Clozapine katon duwe risiko paling dhuwur banjur olanzapine lan quetiapine
Panyurangan ing risiko acara bunuh diri lan prilaku: Clozapine katon luwih unggul tinimbang olanzapine
Penghentian amarga efek samping: Clozapine nduweni tingkat penghentian paling dhuwur ing jangka pendek nanging tingkat paling murah tinimbang antipsikotik ing jangka panjang (rong taun utawa luwih). )
Risperidone katon duwe tingkat EPS sing luwih dhuwur tinimbang olanzapine
Risperidone bisa uga duwe tingkat disfungsi seksual sing luwih dhuwur dibandhingake karo quetiapine, nanging tingkat sing padha yen dibandhingake karo ziprasidone
Wanita bisa uga luwih responsif marang clozapine lan olanzapine tinimbang wong lanang.

Kanthi prabédan antarane antipsikotik atipikal lan antipsikotik khas, antipsikotik atipikal kurang bisa ngasilake EPS nanging luwih cenderung nyebabake bobot awak. gain. Bubar, ora ana bedane efektifitas babagan perbaikan gejala antarane antipsikotik atipikal lan antipsikotik khas wis ditampilake.

Antipsikotik Atipikal Umum Kasedhiya ing AS

< td> olanzapine < td> Geodon

Jeneng umum	Conto jeneng merek
aripiprazole	Abilify
asenapine	Saphris
brexpiprazole	Rexulti
cariprazine	Vraylar
clozapine	Clozaril, FazaClo
iloperidone	Fanapt
lurasidone	Latuda
Zyprexa
paliperidone	Invega
quetiapine< /td>	Seroquel
risperidone	Risperdal
ziprasidone

Apa antipsikotik atipikal aman?

Kabeh obat duwe risiko lan mupangat lan antipsikotik atipikal ora kajaba. Nalika dijupuk kaya sing diwenehake dening dokter ing wong sing ora duwe contraindications kanggo nggunakake, antipsikotik atipikal dianggep aman; Nanging, sawetara, kayata clozapine, mbutuhake pemantauan terus-terusan.

Kira-kira 1 saka 10 wong sing njupuk clozapine ngalami neutropenia, yaiku mundhut kapasitas ngasilake sel getih putih sing dibutuhake kanggo nglawan infeksi. Iki bisa nyebabake infeksi serius lan bisa nyebabake pati. Sapa wae sing njupuk clozapine mbutuhake tes getih biasa kanggo mriksa jumlah sel getih. Clozapine uga bisa nyebabake owah-owahan denyut jantung utawa tekanan getih, konstipasi, salivasi sing berlebihan, sedasi, utawa bobot awak. Nanging, ora cenderung nyebabake gejala sing gegandhengan karo gerakan kayata EPS.

Kabeh antipsikotik digandhengake karo tambah risiko pati nalika digunakake ing wong tuwa, utamane sing nandhang demensia, lan ora disetujoni. nggunakake iki. Kajaba iku, antipsikotik atipikal bisa nyebabake owah-owahan ing metabolisme lan nambah risiko diabetes lan kolesterol dhuwur.

Apa efek samping saka antipsikotik atipikal?

Antipsikotik atipikal luwih cenderung tinimbang antipsikotik khas. antipsikotik sing nyebabake bobot lan gangguan metabolisme kalebu paningkatan insiden diabetes tipe 2 lan kolesterol dhuwur.

Efek samping liyane sing umum kalebu:

kangel konsentrasi utawa ngomong< /li>
owah-owahan tekanan getih
sembelit
susah turu
ngiler
ngantuk
rai kaya topeng
rasa gelisah utawa kudu tetep obah
disfungsi seksual
mlaku-mlaku shuffling
tremor
masalah penglihatan (kabur utawa penglihatan ganda).

Kabeh antipsikotik bisa nyebabake rasa ngantuk. Umume antipsikotik digandhengake karo tingkat penghentian sing dhuwur amarga efek samping utawa ora ana efek.

Dhaptar obat karo Antipsikotik atipikal

Jeneng Obat
Abilify Generic name: Aripiprazole (oral)
Abilify (Aripiprazole Intramuscular) Generic name: Aripiprazole
Abilify (Aripiprazole Oral) Generic name: Aripiprazole
Abilify Discmelt Generic name: Aripiprazole
Abilify Maintena Generic name: Aripiprazole Lauroxil (injection)
Abilify Maintena Prefilled Syringe injection Generic name: Aripiprazole (injection)
Abilify Mycite Generic name: Aripiprazole
Abilify MyCite Maintenance Kit oral with sensor Generic name: Aripiprazole (oral With Sensor)
Abilify MyCite Starter Kit oral with sensor Generic name: Aripiprazole (oral With Sensor)
Aripiprazole Generic name: Aripiprazole (oral)
Aripiprazole (Intramuscular) Generic name: Aripiprazole
Aripiprazole (Oral) Generic name: Aripiprazole
Aripiprazole injection Generic name: Aripiprazole (injection)
Aripiprazole lauroxil Generic name: Aripiprazole Lauroxil
Aripiprazole oral with sensor Generic name: Aripiprazole (oral With Sensor)
Aristada Generic name: Aripiprazole Lauroxil (injection)
Aristada Initio Generic name: Aripiprazole Lauroxil
Aristada Initio injection Generic name: Aripiprazole (injection)
Aristada injection Generic name: Aripiprazole (injection)
Asenapine sublingual Generic name: Asenapine (sublingual)
Asenapine transdermal Generic name: Asenapine (transdermal)
Clozapine Generic name: Clozapine
Clozaril Generic name: Clozapine
Brexpiprazole Generic name: Brexpiprazole
Caplyta Generic name: Lumateperone
Cariprazine Generic name: Cariprazine
Fanapt Generic name: Iloperidone
Fanapt Titration Pack Generic name: Iloperidone
Fazaclo Generic name: Clozapine
Geodon Generic name: Ziprasidone
Geodon (Ziprasidone Intramuscular) Generic name: Ziprasidone
Geodon (Ziprasidone Oral) Generic name: Ziprasidone
Iloperidone Generic name: Iloperidone
Invega Generic name: Paliperidone (oral)
Invega Hafyera Generic name: Paliperidone Palmitate
Invega Hafyera injection Generic name: Paliperidone (injection)
Invega Sustenna Generic name: Paliperidone (injection)
Invega Trinza Generic name: Paliperidone Palminate
Latuda Generic name: Lurasidone
Lumateperone Generic name: Lumateperone
Lurasidone Generic name: Lurasidone
Nuplazid Generic name: Pimavanserin
Olanzapine Generic name: Olanzapine (oral)
Olanzapine (Intramuscular) Generic name: Olanzapine
Olanzapine (Oral) Generic name: Olanzapine
Olanzapine injection Generic name: Olanzapine (injection)
Paliperidone Generic name: Paliperidone (oral)
Paliperidone (Intramuscular) Generic name: Paliperidone
Paliperidone (Oral) Generic name: Paliperidone
Paliperidone injection Generic name: Paliperidone (injection)
Perseris Generic name: Risperidone
Perseris injection Generic name: Risperidone (injection)
Pimavanserin Generic name: Pimavanserin
Quetiapine Generic name: Quetiapine
Rexulti Generic name: Brexpiprazole
Risperdal Generic name: Risperidone (oral)
Risperdal Consta Generic name: Risperidone (injection)
Risperdal M-Tab Generic name: Risperidone
Risperidone Generic name: Risperidone (oral)
Risperidone (Intramuscular, Subcutaneous) Generic name: Risperidone
Risperidone (Oral) Generic name: Risperidone
Risperidone injection Generic name: Risperidone (injection)
RisperiDONE M-Tab Generic name: Risperidone
Rykindo Generic name: Risperidone
Saphris Generic name: Asenapine (sublingual)
Secuado Generic name: Asenapine
Secuado transdermal Generic name: Asenapine (transdermal)
Seroquel Generic name: Quetiapine
Seroquel XR Generic name: Quetiapine
Uzedy Generic name: Risperidone (injection)
Uzedy injection Generic name: Risperidone (injection)
Versacloz Generic name: Clozapine
Vraylar Generic name: Cariprazine
Ziprasidone Generic name: Ziprasidone (oral/injection)
Ziprasidone (Intramuscular) Generic name: Ziprasidone
Ziprasidone (Oral) Generic name: Ziprasidone
Zyprexa Generic name: Olanzapine (oral)
ZyPREXA injection Generic name: Olanzapine (injection)
Zyprexa IntraMuscular Generic name: Olanzapine
Zyprexa Relprevv Generic name: Olanzapine (injection)
Zyprexa Zydis Generic name: Olanzapine (oral)

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