Glukokortikoid
Apa iku Glucocorticoids?
Glucocorticoids minangka jinis hormon kortikosteroid sing efektif banget kanggo nyuda inflamasi lan nyuda sistem kekebalan. Inflamasi minangka cara sistem kekebalan awak nanggapi zat lan trauma sing mbebayani lan minangka bagean saka proses penyembuhan. Nanging, yen mekanisme kontrol biasa sing mateni proses inflamasi ora bisa mlaku kanthi bener lan terus terus-terusan, jaringan bisa rusak. Peradangan terus-terusan digandhengake karo akeh kahanan kronis.
Apa glukokortikoid dianggep aman?
Yen diwenehi dosis sing disaranake kanggo wektu sing cendhak, glukokortikoid dianggep aman. Dosis glukokortikoid siji-siji, sanajan gedhe, utawa terapi jangka pendek kurang saka seminggu duwe efek sing mbebayani. Nanging, dosis sing luwih reguler utawa ditambah wis digandhengake karo sawetara efek samping sing abot.
- Yen glukokortikoid diwenehake saben dina (kanthi dosis sing padha karo prednison 15mg / dina luwih saka telung). minggu), kelenjar adrenal mandheg ngasilake glukokortikoid lan jaringan ing korteks adrenal wiwit atrofi (mati). Iki kuwatir yen glukokortikoid tiba-tiba mandheg amarga jaringan adrenal ora bakal langsung ngasilake glukokortikoid maneh. Iki diarani insufisiensi adrenal akut lan gejala kalebu irritability, mual, nyeri sendi, pusing lan tekanan darah rendah. Kanggo ngindhari kedadeyan kasebut, obat steroid kudu ditarik alon-alon, sajrone sawetara minggu utawa sasi, supaya korteks adrenal bisa nerusake fungsine kanthi lengkap.
- Kanggo wong sing njupuk glukokortikoid, dosis ekstra jangka panjang. glukokortikoid kudu diwenehi nalika stres akut, kayata infèksi abot utawa operasi, kanggo niru lonjakan kortisol sing biasane diasilake dening awak nalika kedadeyan sing nyebabake stres, yen ora, penyembuhan bisa ditundha utawa ora lengkap.
- Dosis glukokortikoid ing wayah sore kudu ora dianjurake amarga bisa nyebabake insomnia. Nanging, glukokortikoid biasane dijupuk mung sapisan dina, utawa yen dijupuk kaping pindho saben dina, kudu diwenehi dosis ing wayah esuk lan maneh ing wayah awan.
- Amarga glukokortikoid nyuda sistem kekebalan, nambah risiko infeksi. . Infèksi virus tartamtu, kayata cacar air utawa campak bisa uga luwih abot ing wong sing njupuk glukokortikoid.
- Panganggone glukokortikoid ing wektu sing suwe uga bisa nyebabake sindrom Cushing. Gejala kalebu punuk lemak ing antarane pundhak, pasuryan bunder, bobot awak, siklus menstruasi ora teratur, lemes, lan depresi.
Kanggo dhaptar lengkap efek samping sing abot, mangga deleng individu kasebut. monograf obat.
Apa efek samping sing umum saka glukokortikoid?
Glucocorticoids wis digandhengake karo sawetara efek samping sing umum kalebu:
- Agitasi lan irritability
- Paningal kabur
- Katarak utawa glaukoma
- Kesulitan konsentrasi
- Pusing
- Wuwuh rambut ing rai wanita li>
- Detak jantung sing cepet utawa ora teratur
- Retensi cairan
- Sakit sirah
- Tekanan darah tinggi
- Tambah gula getih, kolesterol , utawa tingkat trigliserida
- Tambah risiko ulkus lambung utawa gastritis
- Mundhut kalium
- Osteoporosis amarga nyuda kemampuan awak kanggo nyerep kalsium< /li>
- Reaktivasi tuberkulosis laten
- Sesak ambegan
- Ngantuk
- Bobot tambah.
Kanggo dhaptar lengkap efek samping, mangga deleng monograf obat individu.
Dhaptar obat karo Glukokortikoid
Jeneng Obat |
---|
A-Hydrocort Generic name: Hydrocortisone |
Alkindi Sprinkle Generic name: Hydrocortisone (oral) |
A-Methapred Generic name: Methylprednisolone |
A-Methapred injection Generic name: Methylprednisolone (injection) |
Aristocort Generic name: Triamcinolone |
Aristocort Forte Generic name: Triamcinolone |
Aristospan Generic name: Triamcinolone |
Azmacort Generic name: Triamcinolone Inhalation |
Clinacort Generic name: Triamcinolone |
Cortef Generic name: Hydrocortisone (oral) |
Cortenema foam, enema Generic name: Hydrocortisone Rectal (foam, Enema) |
Cortifoam foam, enema Generic name: Hydrocortisone Rectal (foam, Enema) |
Cortisone Generic name: Cortisone |
Cotolone Generic name: Prednisolone |
Baycadron Elixer Generic name: Dexamethasone |
Betamethasone injection Generic name: Betamethasone (injection) |
Betamethasone sodium phosphate and betamethasone acetate Generic name: Betamethasone Sodium Phosphate And Betamethasone Acetate |
Bubbli-Pred Generic name: Prednisolone |
Celestone Soluspan Generic name: Betamethasone Sodium Phosphate And Betamethasone Acetate |
Celestone Soluspan injection Generic name: Betamethasone (injection) |
De-Sone LA injection Generic name: Dexamethasone (injection) |
Decadron Generic name: Dexamethasone (oral) |
Decadron injection Generic name: Dexamethasone (injection) |
Deflazacort Generic name: Deflazacort |
Dekpak 13 Day Taperpak Generic name: Dexamethasone |
Deltasone Generic name: Prednisone |
Depo-Medrol Generic name: Methylprednisolone |
Depo-Medrol injection Generic name: Methylprednisolone (injection) |
Dexabliss 11-Day Dose Pack Generic name: Dexamethasone (oral) |
Dexamethasone Generic name: Dexamethasone (oral) |
Dexamethasone (Oral) Generic name: Dexamethasone |
Dexamethasone injection Generic name: Dexamethasone (injection) |
Dexamethasone Intensol Generic name: Dexamethasone (oral) |
DexPak Generic name: Dexamethasone |
DexPak 10 Day TaperPak Generic name: Dexamethasone |
DexPak 6 DayTaperpak Generic name: Dexamethasone (oral) |
DexPak Jr Generic name: Dexamethasone |
Dxevo 11-Day Dose Pack Generic name: Dexamethasone (oral) |
Emflaza Generic name: Deflazacort |
Entocort EC Generic name: Budesonide (oral) |
Flo-Pred Generic name: Prednisolone |
Hemady Generic name: Dexamethasone (oral) |
Hexatrione injection Generic name: Triamcinolone (injection) |
HiDex 6-Day Taper Package Generic name: Dexamethasone (oral) |
Hydrocortisone Generic name: Hydrocortisone (oral) |
Hydrocortisone (Oral) Generic name: Hydrocortisone |
Hydrocortisone injection Generic name: Hydrocortisone (injection) |
Hydrocortisone rectal foam, enema Generic name: Hydrocortisone Rectal (foam, Enema) |
Kenalog-10 Generic name: Triamcinolone |
Kenalog-10 injection Generic name: Triamcinolone (injection) |
Kenalog-40 Generic name: Triamcinolone Acetonide 40mg/mL |
Kenalog-80 injection Generic name: Triamcinolone (injection) |
Medrol Generic name: Methylprednisolone (oral) |
Medrol Dosepak Generic name: Methylprednisolone (oral) |
Methylpred-DP Generic name: Methylprednisolone |
Methylprednisolone Generic name: Methylprednisolone (oral) |
Methylprednisolone (Oral) Generic name: Methylprednisolone |
MethylPREDNISolone Dose Pack Generic name: Methylprednisolone (oral) |
Methylprednisolone injection Generic name: Methylprednisolone (injection) |
Millipred Generic name: Prednisolone |
Millipred DP Generic name: Prednisolone |
Orapred ODT Generic name: Prednisolone |
Ortikos Generic name: Budesonide (oral) |
Pediapred Generic name: Prednisolone |
Prednicot Generic name: Prednisone |
Prednisolone Generic name: Prednisolone |
Prednisolone (Oral) Generic name: Prednisolone |
Prednisone Generic name: Prednisone |
Prednisone Intensol Generic name: Prednisone |
Prelone Generic name: Prednisolone |
Rayos Generic name: Prednisone |
Solu-CORTEF injection Generic name: Hydrocortisone (injection) |
Solu-MEDROL injection Generic name: Methylprednisolone (injection) |
SoluCORTEF Generic name: Hydrocortisone |
SoluMEDROL Generic name: Methylprednisolone |
Sterapred Generic name: Prednisone |
Sterapred DS Generic name: Prednisone |
TaperDex 12-Day Generic name: Dexamethasone (oral) |
TaperDex 6-Day Generic name: Dexamethasone (oral) |
TaperDex 7-Day Generic name: Dexamethasone (oral) |
Tarpeyo Generic name: Budesonide |
Triam-Forte Generic name: Triamcinolone |
Triamcinolone Generic name: Triamcinolone (oral) |
Triamcinolone (Intra-articular) Generic name: Triamcinolone |
Triamcinolone injection Generic name: Triamcinolone (injection) |
Triamcot (Triamcinolone Injection) Generic name: Triamcinolone |
Triesense Generic name: Triamcinolone |
Uceris Generic name: Budesonide (oral) |
Uceris (Budesonide Oral) Generic name: Budesonide |
Uceris (Budesonide Rectal) Generic name: Budesonide |
Veripred 20 Generic name: Prednisolone |
Zcort 7-Day Generic name: Dexamethasone (oral) |
Zema-Pak Generic name: Dexamethasone |
Zilretta Generic name: Triamcinolone Acetonide (injection) |
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