inhibitor HER2
Apa iku inhibitor HER2?
Human epidermal growth factor receptor (HER2) inhibitor yaiku inhibitor tyrosine kinase utawa antibodi monoklonal sing nyepetake utawa nyetop pertumbuhan sel.
Reseptor faktor pertumbuhan epidermis manungsa yaiku reseptor transmembrane; padha duwe komponèn ikatan ekstraselular, komponèn transmembran lan komponèn tirosin kinase intraselular. Sawetara kanker payudara duwe ekspresi HER2 sing berlebihan sing nyebabake tuwuhing sel lan panyebaran sel kanker.
Inhibitor tirosin kinase ngiket domain tyrosine kinase ing HER2 lan mungkasi aktivasi jalur sinyal. Antibodi monoklonal ikatan karo komponen ekstraselular saka HER2, nyegah substrat nyata saka ikatan karo reseptor lan mungkasi aktivasi reseptor.
Inhibitor HER2 digunakake kanggo perawatan kanker payudara.
Dhaptar obat karo inhibitor HER2
Jeneng Obat |
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Ado-trastuzumab emtansine Generic name: Ado-trastuzumab Emtansine |
Enhertu Generic name: Fam-trastuzumab Deruxtecan |
Fam-trastuzumab deruxtecan Generic name: Fam-trastuzumab Deruxtecan |
Fam-trastuzumab deruxtecan-nxki Generic name: Fam-trastuzumab Deruxtecan-nxki |
Herceptin Generic name: Trastuzumab |
Herceptin Hylecta Generic name: Trastuzumab And Hyaluronidase-oysk |
Herzuma Generic name: Trastuzumab |
Herzuma (Trastuzumab Intravenous) Generic name: Trastuzumab |
Herzuma (Trastuzumab-pkrb Intravenous) Generic name: Trastuzumab-pkrb |
Hyaluronidase and trastuzumab Generic name: Hyaluronidase And Trastuzumab |
Hyaluronidase, pertuzumab, and trastuzumab Generic name: Hyaluronidase, Pertuzumab, And Trastuzumab |
Kadcyla Generic name: Ado-trastuzumab Emtansine |
Margenza Generic name: Margetuximab |
Margetuximab Generic name: Margetuximab |
Margetuximab-cmkb Generic name: Margetuximab-cmkb |
Ogivri Generic name: Trastuzumab |
Ogivri (Trastuzumab Intravenous) Generic name: Trastuzumab |
Ogivri (Trastuzumab-dkst Intravenous) Generic name: Trastuzumab-dkst |
Ontruzant Generic name: Trastuzumab |
Ontruzant (Trastuzumab Intravenous) Generic name: Trastuzumab |
Ontruzant (Trastuzumab-dttb Intravenous) Generic name: Trastuzumab-dttb |
Perjeta Generic name: Pertuzumab |
Pertuzumab Generic name: Pertuzumab |
Pertuzumab, trastuzumab, and hyaluronidase-zzxf Generic name: Pertuzumab, Trastuzumab, And Hyaluronidase-zzxf |
Phesgo Generic name: Hyaluronidase, Pertuzumab, And Trastuzumab |
Trastuzumab Generic name: Trastuzumab |
Trastuzumab and hyaluronidase-oysk Generic name: Trastuzumab And Hyaluronidase-oysk |
Trastuzumab-anns Generic name: Trastuzumab-anns |
Trastuzumab-dkst Generic name: Trastuzumab-dkst |
Trastuzumab-dttb Generic name: Trastuzumab-dttb |
Trastuzumab-pkrb Generic name: Trastuzumab-pkrb |
Trazimera Generic name: Trastuzumab-qyyp |
Tucatinib Generic name: Tucatinib |
Tukysa Generic name: Tucatinib |
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