Anti-inflamasi non-steroid topikal
Apa iku anti-inflamasi non-steroid topikal?
Anti-inflamasi non-steroid topikal (asring disingkat NSAID) yaiku krim, gel, rubs, larutan utawa semprotan sing ngandhut anti-inflamasi nonsteroid. agen lan dirancang kanggo ditrapake langsung menyang kulit sing nutupi sendi utawa area balung sing nyeri. Iki digunakake kanggo nyuda rasa nyeri lan ngobati gejala arthritis kayata inflamasi, bengkak, lan kaku. NSAID topikal uga bisa digunakake kanggo perawatan actinic keratosis (patch precancerous saka kulit kandel, scaly utawa crusted).
NSAIDs nduweni anti-inflamasi (ngurangi inflamasi), analgesik (ngilangake rasa nyeri) lan antipiretik ( suhu ngisor) efek. Senadyan NSAID beda duwe struktur sing beda-beda, kabeh mau kerjane kanthi ngalangi enzim cyclooxygenase (COX). Ana rong jinis utama enzim COX: COX-1 lan COX-2. Loro-lorone jinis ngasilake prostaglandin; Nanging, fungsi utama enzim COX-1 yaiku ngasilake tingkat prostaglandin awal sing ngaktifake trombosit lan nglindhungi lapisan saluran pencernaan, dene enzim COX-2 tanggung jawab kanggo ngeculake prostaglandin sawise infeksi utawa ciloko. Prostaglandin duwe sawetara efek sing beda, salah sijine yaiku ngatur inflamasi. Umume NSAID nyandhet enzim loro kasebut, sanajan sawetara kasedhiya sing utamane nyandhet COX-2. Efek nyeri lan anti-inflamasi saka NSAID utamane amarga inhibisi COX-2, lan efek samping sing ora dikarepake amarga inhibisi COX-1.
NSAID topikal luwih cenderung tinimbang lisan. NSAIDs nyebabake efek samping gastrointestinal utawa sesambungan karo obat liya, sanajan wong tuwa bisa uga luwih rentan marang efek kasebut. Sing umure cendhak, abang entheng ing situs aplikasi minangka efek samping sing paling umum dilaporake.
Dhaptar obat karo Anti-inflamasi non-steroid topikal
Jeneng Obat |
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Aspercreme Arthritis Pain Generic name: Diclofenac Topical |
Capsaicin and diclofenac topical Generic name: Capsaicin And Diclofenac (topical) |
DermacinRx Lexitral PharmaPak topical Generic name: Capsaicin And Diclofenac (topical) |
Diclofenac (Topical application) Generic name: Diclofenac |
Diclofenac and menthol topical Generic name: Diclofenac And Menthol Topical |
Diclofenac topical Generic name: Diclofenac Topical |
Diclofenac transdermal Generic name: Diclofenac Topical System (patch) |
DicloPrep-100 Generic name: Diclofenac Topical |
DicloStream Generic name: Diclofenac And Menthol Topical |
Diclotral Pak topical Generic name: Capsaicin And Diclofenac (topical) |
Flector Generic name: Diclofenac Topical System (patch) |
Klofensaid II Generic name: Diclofenac |
Licart Generic name: Diclofenac |
Motrin Arthritis Pain Generic name: Diclofenac Topical |
Pennsaid Generic name: Diclofenac Topical |
Rexaphenac Generic name: Diclofenac Topical |
Salonpas Arthritis Pain Relief Generic name: Diclofenac Topical |
Solaraze Generic name: Diclofenac Topical |
Voltaren (Diclofenac Topical application) Generic name: Diclofenac |
Voltaren Arthritis Pain Generic name: Diclofenac Topical |
Voltaren Arthritis Pain Gel Generic name: Diclofenac Topical |
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