Candida Albicans Skin Test Antigen
Kelas obat: Agen Antineoplastik
Panganggone Candida Albicans Skin Test Antigen
Hipersensitivitas Seluler
Digunakake minangka antigen kelingan kanggo ndeteksi hipersensitivitas sing dimediasi sel kanggo Candida albicans.
Bisa digunakake kanggo ngevaluasi respon imun seluler ing pasien sing dicurigai ngalami penurunan sel. hipersensitifitas.
Sawetara wong sing duwe kekebalan seluler normal bisa uga ora hipersensitif marang Candida; mula, disaranake nggunakake bebarengan antigen tes kulit hipersensitivitas sel-mediated liyane sing dilisensi.
Infeksi HIV bisa ngowahi respon hipersensitivitas tipe telat (DTH) tumrap tuberkulin; mulane, dianjurake kanggo nguji pasien sing kena infeksi HIV kanthi risiko tuberkulosis kanthi antigen saliyane tuberkulin.
Aja digunakake kanggo diagnosa utawa nambani alergi Tipe 1 kanggo Candida albicans.
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Carane nggunakake Candida Albicans Skin Test Antigen
Umum
Pantauan Pasien
Pangawasan Dispa lan Administrasi
Administrasi
Administrasi intradermal; aja nyuntik IV. Ati-ati supaya ora injeksi menyang pembuluh getih.
Atur injeksi intradermal menyang permukaan volar lengen utawa sisih njaba lengen ndhuwur. Kudu ngatur minangka superficially sabisa nyebabake bleb, cetha ditetepake cetha. Reaksi sing ora bisa dipercaya bisa nyebabake yen produk disuntikake sub-Q.
Resiki kulit nganggo alkohol 70% sadurunge nggunakake tes kulit.
Dosis
Dewasa
Injeksi Intradermal Hipersensitivitas SelularDosis sing digunakake kanggo netepake hipersensitivitas seluler yaiku 0,1 mL.
Wektu sing dibutuhake kanggo respon indurasi tekan intensitas maksimal beda-beda. Reaksi kasebut biasane diwiwiti sajrone 24 jam lan puncak ing antarane 24 nganti 48 jam.
Waca tes kulit ing 48 jam kanthi mriksa lokasi tes kanthi visual lan palpasi area indurasi. Indurasi ≥5 mm dianggep minangka reaksi hipersensitivitas tipe tundha positif (DTH).
Pènget
Kontraindikasi
Pènget / PancegahanPènget
Reaksi Saleh sing Serius
Reaksi sing luwih gedhe tinimbang respon lokal sing dikarepake bisa kedadeyan sawise administrasi tes kulit. (Deleng Warning Boxed.)
Reaksi sistemik sing ngancam nyawa utawa fatal bisa kedadeyan. Laporake reaksi ala sing serius menyang pabrikan utawa FDA.
Pancegahan Administrasi
Antigen tes kulit Candida albicans kudu disuntikake intradermal sabisane, nyebabake bleb sing jelas lan jelas ing situs tes kulit. Reaksi sing ora bisa dipercaya bisa nyebabake yen produk disuntikake sub-Q. Ora kudu ngurus IV; ati-ati supaya ora nyuntikake menyang pembuluh getih.
Gunakake jarum suntik lan jarum steril sing kapisah kanggo saben pasien kanggo nyegah panularan agen infèksius. Mbuwang jarum kanthi bener lan aja recap.
Pesthekake yen fasilitas, peralatan, lan obat-obatan (epinefrin, oksigen) sing dibutuhake kanggo ngobati efek samping sing potensial kasedhiya.
Aja menehi IV . (pirsani Boxed Warning.)
Reaksi Lokal lan Sistemik
Kaya kabeh antigen tes kulit, reaksi alergi lokal lan sistemik bisa kedadeyan.
Reaksi lokal kalebu pembengkakan, pruritus, lan vesikulasi. Necrosis lan ulceration ora diamati, nanging miturut teori bisa. Reaksi lokal bisa diobati kanthi kompres dingin lan steroid topikal. Reaksi lokal sing abot (umpamane, ruam, vesikulasi, bula, exfoliation dermal, selulitis) bisa uga ing wong sing alergi banget; bisa uga mbutuhake langkah-langkah tambahan sing cocog.
Ing wong sing cenderung pendarahan, trauma saka tes kulit bisa nyebabake bruising lan indurasi nonspesifik.
Reaksi hipersensitivitas langsung lokal bisa kedadeyan. Reaksi kasebut ditondoi kanthi edematous hive sing diubengi dening zona eritema lan diamati kira-kira 15-20 menit sawise injeksi intradermal.
Reaksi sistemik ora diamati, nanging bisa. Reaksi sistemik biasane kedadeyan sajrone 30 menit sawise injeksi antigen lan bisa uga kalebu gejala ing ngisor iki: wahing, watuk, gatal, sesak ambegan, kram weteng, muntah, diare, tachycardia, hipotensi, lan gagal ambegan ing kasus sing abot.
Reaksi alergi sistemik (contone, anafilaksis) kudu langsung diobati nganggo epinefrin HCl 1:1.000. Tindakan tambahan bisa uga dibutuhake, gumantung saka keruwetan.
Populasi Spesifik
KandhutanOra dingerteni manawa antigen tes kulit candida albicans bisa nyebabake cilaka janin utawa mengaruhi kapasitas reproduksi. Pasinaon reproduksi kewan ora ditindakake. Gunakake ing wanita ngandhut mung yen cetha dibutuhake.
LaktasiOra dingerteni manawa antigen tes kulit candida albicans diekskresi ing susu manungsa. Ati-ati nalika menehi kanggo wanita sing nyusoni.
Panggunaan PediatrikKeamanan lan efektifitas ora ditetepake ing bocah-bocah. Nanging, tes kulit wis digunakake ing pasien pediatrik kanggo ngevaluasi kekebalan seluler.
Panggunaan GeriatrikOra ditliti kanthi cukup ing pasien geriatik; Nanging, pasien kasebut bisa uga kurang respon amarga proses tuwa dikenal bisa ngowahi kekebalan sing dimediasi sel.
Efek Samsaya Awon
Reaksi lokal hipersensitivitas langsung bisa kalebu gatal, bengkak, nyeri, lan blistering ing situs tes sing kedadeyan 15-20 menit sawise administrasi. Necrosis bisa uga.
Reaksi sistemik ora diamati; Nanging, kabeh antigen asing duwe kemungkinan adoh nyebabake anafilaksis Tipe 1 lan malah mati nalika disuntikake intradermal.
Apa obatan liyane bakal mengaruhi Candida Albicans Skin Test Antigen
Kortikosteroid lan Obat Imunosupresif
Dosis farmakologis kortikosteroid bisa nyuda respon tes kulit DTH sawise terapi 2 minggu. Tanggapan biasane bali menyang tingkat pretreatment sajrone sawetara minggu sawise terapi steroid dihentikan.
Obat-Obat Pamblokir Beta
Pasien sing nampa obat-obatan pamblokiran beta bisa uga ora nanggapi dosis epinefrin sing biasa, ing acara yen epinefrin dibutuhake kanggo ngontrol reaksi alergi sing ala.
Disclaimer
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Ora ana bebaya kanggo kombinasi obat utawa obat sing diwenehake kanthi cara apa wae kudu ditafsirake kanggo nuduhake yen obat utawa kombinasi obat kasebut aman, efektif utawa cocok kanggo pasien tartamtu. Drugslib.com ora nanggung tanggung jawab kanggo aspek kesehatan apa wae sing ditindakake kanthi bantuan informasi sing diwenehake Drugslib.com. Informasi sing ana ing kene ora dimaksudake kanggo nyakup kabeh panggunaan, pituduh, pancegahan, bebaya, interaksi obat, reaksi alergi, utawa efek samping. Yen sampeyan duwe pitakon babagan obat sing sampeyan gunakake, takon dhokter, perawat utawa apoteker.
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