Cantharidin (Topical)
Jeneng merek: Ycanth
Kelas obat:
Agen Antineoplastik
Panganggone Cantharidin (Topical)
Cantharidin nduweni kegunaan ing ngisor iki:
Solusi topikal Cantharidin dituduhake kanggo perawatan moluskum contagiosum ing pasien diwasa lan bocah umur 2 taun lan luwih.
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Carane nggunakake Cantharidin (Topical)
Umum
Cantharidin kasedhiya ing wangun dosis lan kekuatan:
Solusi topikal sing ngandhut 0,7% cantharidin; disedhiyakake ing ampul kaca sing ana ing aplikator siji-kanggone.
Dosis
Penting pelabelan pabrikan kudu dikonsultasi kanggo luwih rinci. informasi babagan dosis lan administrasi obat iki. Ringkesan dosis:
Kabeh profesional kesehatan kudu nampa instruksi lan latihan sadurunge nyiapake lan administrasi cantharidin.
Gunakake sarung tangan nitrile utawa vinyl lan proteksi mripat sajrone nyiapake lan administrasi.
Mung kanggo panggunaan topikal. Ora kanggo panggunaan lisan, mukosa, utawa ophthalmic.
Pasien Pediatrik
Dewasa
Dosis lan AdministrasiPènget
Kontraindikasi
Ora ana
Pènget / PancegahanToksisitas sing Digandhengake karo Administrasi sing Ora Cocok
Cantharidin mung kanggo panggunaan topikal. Cantharidin ora kanggo panggunaan lisan, mukosa, utawa ophthalmic.
Toksisitas sing ngancam nyawa utawa fatal bisa kedadeyan yen cantharidin diwenehake kanthi lisan. Reaksi salabetipun kanggo ingestion lisan saka cantharidin kalebu gagal ginjel, blistering lan karusakan abot ing saluran gastrointestinal, koagulopati, kejang, lan lumpuh flaccid. Anjurake pasien lan/utawa pengasuh supaya ora kena kontak lisan lan supaya ora nrenyuhake lesi sawise perawatan cantharidin lan njaluk bantuan medis langsung yen cantharidin ora disengaja.
Toksisitas okular bisa kedadeyan yen cantharidin kena mata. Reaksi salabetipun saka kontak cantharidin karo mata bisa kalebu nekrosis kornea, perforasi okular, lan ciloko okular jero. Aja nggunakake cantharidin ing cedhak utawa ing mripat. Yen cantharidin kena mripat, siram mripat nganggo banyu paling sethithik 15 menit lan langsung golek dhokter.
Reaksi Kulit Lokal
Cantharidin minangka vesicant. Reaksi kulit lokal ing situs aplikasi diamati ing 97% subjek sing diobati karo cantharidin sajrone uji klinis. Reaksi kulit lokal kalebu vesikulasi, pruritus, nyeri, perubahan warna, lan eritema.
Aja aplikasi ing cedhak mata lan jaringan mukosa, lan kanggo kulit sehat jejer. Yen cantharidin kena permukaan sing ora disengaja, kalebu kulit sing sehat, enggal copot kanthi ngusap nganggo swab katun utawa kasa.
Hindari produk topikal liyane (umpamane, krim, lotion, utawa tabir surya) ing wilayah sing diobati nganti 24 jam sawise perawatan cantharidin utawa nganti ngumbah. Aplikasi saka produk topikal liyane bisa nyebar cantharidin lan nyebabake blistering utawa reaksi salabetipun liyane kanggo kulit sehat.
Yen blistering abot, pain abot utawa reaksi salabetipun abot, mbusak cantharidin sadurunge dianjurake 24 jam sawise administrasi dening ngumbah nganggo sabun lan banyu.
Kebakaran
Cantharidin minangka cairan sing gampang kobong, sanajan wis garing. Aja geni, geni utawa udud ing cedhak lesi sajrone perawatan lan sawise aplikasi nganti dibusak.
Populasi Tertentu
KandhutanOra ana data sing kasedhiya babagan panggunaan cantharidin ing wanita ngandhut kanggo ngevaluasi risiko sing ana gandhengane karo obat-obatan saka cacat lair utama, keguguran utawa asil ibu utawa janin sing ora becik. Pasinaon reproduksi kewan ora ditindakake kanthi cantharidin. Amarga pajanan sistemik kanggo cantharidin sawise administrasi topikal kurang, panggunaan ibu ora bakal nyebabake paparan obat kasebut marang janin.
Risiko latar mburi cacat lair utama lan keguguran kanggo populasi sing dituduhake ora dingerteni. Kabeh meteng duwe risiko latar mburi cacat lair, mundhut, utawa asil salabetipun liyane. Ing populasi umum AS, kira-kira risiko latar mburi cacat lair utama lan keguguran ing kandhutan sing diakoni sacara klinis yaiku 2% nganti 4% lan 15% nganti 20%.
LaktasiAja nggunakake solusi topikal cantharidin kanggo wilayah kanthi risiko tambah potensial kanggo ingestion dening utawa cahya ocular kanggo anak sing nyusoni. Ora ana data babagan anané cantharidin ing susu manungsa utawa kewan, utawa efek ing bayi sing disusui utawa ing produksi susu. Nyusoni ora bakal nyebabake paparan obat kasebut amarga panyerepan sistemik cantharidin sing kurang sawise administrasi topikal. Mupangat pangembangan lan kesehatan saka nyusoni kudu dianggep bebarengan karo kabutuhan klinis ibu kanggo solusi topikal cantharidin lan efek samping sing potensial kanggo bocah sing nyusoni saka solusi topikal cantharidin utawa saka kondisi ibu sing ndasari.
Panggunaan PediatrikThe safety lan efektifitas cantharidin kanggo perawatan moluskum contagiosum wis ditetepake ing pasien pediatrik umur 2 taun utawa luwih. Panganggone cantharidin ing pasien pediatrik didhukung dening asil saka uji coba sing cukup lan dikontrol kanthi apik ing pasien umur 2 taun lan luwih lawas; sanajan safety lan khasiat panggunaan obat luwih saka 12 minggu durung ditetepake.
Keamanan lan kesahihan ing pasien pediatrik ing ngisor umur 2 taun durung ditetepake.
Panggunaan GeriatrikCantharidin durung diteliti ing pasien geriatri.
Efek Sabar sing Umum
Reaksi sing paling umum (insiden ≥1%) reaksi salabetipun kalebu reaksi kulit lokal ing situs aplikasi: vesikulasi, nyeri, pruritus, scabbing, eritema, perubahan warna, situs aplikasi. kekeringan, busung, lan erosi.
Apa obatan liyane bakal mengaruhi Cantharidin (Topical)
Obat Spesifik
Iku penting panyedhiya label pabrikan dikonsultasi kanggo informasi sing luwih rinci babagan interaksi karo obat iki, kalebu kemungkinan pangaturan dosis. Sorotan interaksi:
Deleng label produk kanggo informasi interaksi obat.
Disclaimer
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