Docusate Salts
Kelas obat: Agen Antineoplastik
Panganggone Docusate Salts
Sembelit
Digunakake minangka pelunak feces (emolien) kanggo ngilangake konstipasi.
Disenengi kanggo laxatives akeh-mbentuk kanggo nggampangake evakuasi feces ing constipation sing gegandhengan karo hard, bangkekan garing.
Dianggep perawatan pilihan dening akeh dokter kanggo constipation kanak-kanak gadhah hard, garing. feces lan luwih aman lan luwih manjur tinimbang lenga mineral kanggo kondisi sing kudu dihindari straining nalika defecation.
Utama migunani kanggo prophylactically kanggo softening feces lan nyegah defecation nglarani ing pasien sing wis utawa bakal ngalami hemoroid. operasi utawa sing duwe kelainan anorektal liyane utawa nalika iku seng di pengeni kanggo ngindhari straining nalika defecation (contone, sawise surgery weteng, surgery rectal anyar, utawa infark miokard; ing patients karo penyakit vaskular, penyakit saka anus utawa rectum, utawa hernias; langsung postpartum ).
Digunakake minangka pelunak feces kanggo constipation sing gegandhengan karo striktur saka usus besar.
Digunakake kanggo softener impaksi fecal. Luwih aman lan luwih efektif tinimbang lenga mineral. Sawise ngresiki feces sing kena pengaruh karo pelunak bangku, obat pencahar stimulan utawa saline bisa diwenehake kanthi rektal kanggo ngosongake usus besar sing kena pengaruh.
Digunakake kanthi kombinasi karo obat pencahar stimulan (umpamane, senna, bisacodyl) kanggo manajemen jangka panjang. konstipasi sing disebabake opiate.
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Carane nggunakake Docusate Salts
Administrasi
Garam docusate diwenehake kanthi lisan lan uyah natrium uga diwenehake kanthi rektal.
Asupan cairan sing nyukupi nggampangake lemes feces.
Administrasi Oral
Administrasi oral.
Cairan oral (dudu sirup) sodium docusate kudu diencerke karo 120 ml susu, jus woh, utawa susu formula bayi kanggo nutupi rasa pait.Administrasi Rectal
Uyah natrium saka docusate bisa diwenehake kanthi rektal.
Dosis
Diwenehake ing dosis mung cukup gedhe kanggo ngasilake lemes saka feces.
Oral dosis beda-beda gumantung saka keruwetan kondhisi lan respon pasien lan kudu disesuaikan karo respon individu.
Pasien Pediatrik
KonstipasiBisa diwènèhaké ing dosis sing dibagi, nanging biasane siji dosis sadurunge turu wis cukup.
Kaping pisanan, dosis ing pungkasan sing luwih dhuwur saka kisaran dosis bisa uga dibutuhake.
LisanBocah <2 taun: Biasane, 25 mg (kisaran: 20-50 mg) saben dina.
Bocah 2-12 taun: Biasane, 50-150 mg saben dina.
Bocah>12 taun: Biasane, 50-360 mg saben dina.
Oral, Dosis Alternatif (contone, Formulasi Cairan)Bocah <3 taun: 10-40 mg saben dina.
Bocah 3-6 taun: 20-60 mg saben dina. .
Bocah 6-12 taun: 40-150 mg saben dina.
RektalTambahake 50–100 mg sodium docusate minangka cairan oral (ora sirup) menyang enema retensi saline utawa lenga kanggo nggunakake dubur.
Dewasa
Konstipasi OralBiasane, 50-360 mg saben dina.
Oral, Dosis Alternatif (contone, Formulasi Cairan)50-500 mg saben dina.
RektalTambahake 50-100 mg sodium docusate minangka cairan oral (ora sirup) menyang saline utawa enema retensi lenga kanggo nggunakake dubur.
Populasi Khusus
Gangguan Hepatik
Ora ana rekomendasi dosis khusus kanggo gangguan hepatik.
Gangguan Ginjal
Ora ana rekomendasi dosis khusus kanggo gangguan ginjel.
Pasien Geriatrik
Ora ana rekomendasi dosis geriatrik sing spesifik.
Pènget
Kontraindikasi
Pènget/PanandhapPancegahan Umum
Panganggone Kronis utawa Overdosis
Panganggone kronis utawa overdosis obat pencahar bisa nyebabake diare sing terus-terusan, hipokalemia, ilang faktor nutrisi sing penting, lan dehidrasi.
Utamane digandhengake karo obat pencahar stimulan. , nanging nimbang kamungkinan sing katergantungan laxative, constipation kronis, lan mundhut saka fungsi usus normal bisa kedaden karo laxative sak nggunakake long-term.
Panganggone Kombinasi TetepYen digunakake ing kombinasi tetep karo agen liyane, nimbang ati-ati, pancegahan, lan kontraindikasi sing digandhengake karo agen sing bebarengan.
Efek Sabar sing Umum
Efek sing ora bisa ditindakake arang banget. Kadhangkala, nyeri kram GI sing entheng, transitory, diare, utawa ruam bisa kedadeyan. Iritasi tenggorokan sawise administrasi oral larutan natrium docusate.
Apa obatan liyane bakal mengaruhi Docusate Salts
Panyerepan Obat GI
Garam docusate, sing minangka agen aktif permukaan (surfaktan), kanthi teoritis bisa ningkatake panyerepan obat-obatan sing diwenehake kanthi lisan. Sifat surfaktan bisa nggampangake transportasi zat liya ing tembok sel.
Sawetara dokter nyaranake supaya pelunak feces ora diwènèhaké bebarengan karo obat oral sing duwé indeks terapeutik sing kurang.
Obat Spesifik< /h3>
Obat
Interaksi
Komentar
Aspirin
Potensiasi karusakan mukosa usus sing disebabake aspirin
Gunakake bebarengan kanthi ati-ati
Mineral lenga
Nambah GI panyerepan lenga mineral
Aja nggunakake bebarengan
Disclaimer
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