Flurbiprofen (EENT)
Jeneng merek: Ocufen
Kelas obat:
Agen Antineoplastik , Agen Antineoplastik , Agen Antineoplastik , Agen Antineoplastik
Panganggone Flurbiprofen (EENT)
Inhibisi Miosis Intraoperatif
Profilaksis sadurunge operasi okular (contone, ekstraksi katarak) kanggo nyegah utawa nyuda miosis intraoperatif.
Peradangan Okular Pasca Operasi
Wis digunakake kanggo Nyegah lan ngatur inflamasi okular pascaoperasi† [off-label] sing ana gandhengane karo trabeculoplasty laser argon lan cyclocryotherapy.
Cystoid Macular Edema
Wis digunakake kanggo nyegah edema makula cystoid pasca operasi† [off-label] sing ana gandhengane karo ekstraksi katarak.
Inhibisi Neovaskularisasi Kornea
Kacarita nyandhet neovaskularisasi kornea† [off-label] sing diakibatake dening kobong kimia utawa termal utawa nggunakake lensa kontak sing suwe ing riset awal ing kewan.
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- Adenovirus Vaccine
- Aldomet
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- Aluminum Chloride (Topical)
- Ambien
- Ambien CR
- Aminosalicylic Acid
- Anacaulase
- Anacaulase
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- Antacids
- Anthrax Immune Globulin IV (Human)
- Antihemophilic Factor (Recombinant), Fc fusion protein (Systemic)
- Antihemophilic Factor (recombinant), Fc-VWF-XTEN Fusion Protein
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- Antithrombin alfa
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- Antithymocyte Globulin (Equine)
- Antivenin (Latrodectus mactans) (Equine)
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- Articaine
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- Co-trimoxazole
- COVID-19 Vaccine (Janssen) (Systemic)
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- Cromolyn (EENT)
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- CycloSPORINE (EENT)
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- Cysteamine Bitartrate
- Cysteamine Hydrochloride
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- Cytomegalovirus Immune Globulin IV
- A1-Proteinase Inhibitor
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- Bacitracin (EENT)
- Baloxavir
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- Beclomethasone (EENT)
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- Belladonna
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- Benzocaine (EENT)
- Bepotastine
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- Betaxolol (Systemic)
- Bexarotene (Systemic)
- Bismuth Salts
- Botulism Antitoxin (Equine)
- Brimonidine (EENT)
- Brivaracetam
- Brivaracetam
- Brolucizumab
- Brompheniramine
- Budesonide (EENT)
- Budesonide (Systemic, Oral Inhalation)
- Bulk-Forming Laxatives
- Bupivacaine (Local)
- BuPROPion (Systemic)
- Buspar
- Buspar Dividose
- Buspirone
- Butoconazole
- Cabotegravir (Systemic)
- Caffeine/Caffeine and Sodium Benzoate
- Calcitonin
- Calcium oxybate, magnesium oxybate, potassium oxybate, and sodium oxybate
- Calcium Salts
- Calcium, magnesium, potassium, and sodium oxybates
- Candida Albicans Skin Test Antigen
- Cantharidin (Topical)
- Capmatinib (Systemic)
- Carbachol
- Carbamide Peroxide
- Carbamide Peroxide
- Carmustine
- Castor Oil
- Catapres
- Catapres-TTS
- Catapres-TTS-1
- Catapres-TTS-2
- Catapres-TTS-3
- Ceftolozane/Tazobactam (Systemic)
- Cefuroxime
- Centruroides Immune F(ab′)2
- Cetirizine (EENT)
- Charcoal, Activated
- Chloramphenicol
- Chlorhexidine (EENT)
- Chlorhexidine (EENT)
- Cholera Vaccine Live Oral
- Choriogonadotropin Alfa
- Ciclesonide (EENT)
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- Ciprofloxacin (EENT)
- Citrates
- Dacomitinib (Systemic)
- Dapsone (Systemic)
- Dapsone (Systemic)
- Daridorexant
- Darolutamide (Systemic)
- Dasatinib (Systemic)
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- Dayvigo
- Dehydrated Alcohol
- Delafloxacin
- Delandistrogene Moxeparvovec (Systemic)
- Dengue Vaccine Live
- Dexamethasone (EENT)
- Dexamethasone (Systemic)
- Dexmedetomidine
- Dexmedetomidine
- Dexmedetomidine
- Dexmedetomidine (Intravenous)
- Dexmedetomidine (Oromucosal)
- Dexmedetomidine buccal/sublingual
- Dexmedetomidine injection
- Dextran 40
- Diclofenac (Systemic)
- Dihydroergotamine
- Dimethyl Fumarate (Systemic)
- Diphenoxylate
- Diphtheria and Tetanus Toxoids
- Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Adsorbed
- Diroximel Fumarate (Systemic)
- Docusate Salts
- Donislecel-jujn (Systemic)
- Doravirine, Lamivudine, and Tenofovir Disoproxil
- Doxepin (Systemic)
- Doxercalciferol
- Doxycycline (EENT)
- Doxycycline (Systemic)
- Doxycycline (Systemic)
- Doxylamine
- Duraclon
- Duraclon injection
- Dyclonine
- Edaravone
- Edluar
- Efgartigimod Alfa (Systemic)
- Eflornithine
- Eflornithine
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- Elranatamab (Systemic)
- Elvitegravir, Cobicistat, Emtricitabine, and tenofovir Disoproxil Fumarate
- Emicizumab-kxwh (Systemic)
- Emtricitabine and Tenofovir Disoproxil Fumarate
- Entrectinib (Systemic)
- EPINEPHrine (EENT)
- EPINEPHrine (Systemic)
- Erythromycin (EENT)
- Erythromycin (Systemic)
- Estrogen-Progestin Combinations
- Estrogen-Progestin Combinations
- Estrogens, Conjugated
- Estropipate; Estrogens, Esterified
- Eszopiclone
- Ethchlorvynol
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- Fibrinogen (Human)
- Flunisolide (EENT)
- Fluocinolone (EENT)
- Fluorides
- Fluorouracil (Systemic)
- Flurbiprofen (EENT)
- Flurbiprofen (EENT)
- Flurbiprofen (EENT)
- Flurbiprofen (EENT)
- Fluticasone (EENT)
- Fluticasone (Systemic, Oral Inhalation)
- Fluticasone and Vilanterol (Oral Inhalation)
- Ganciclovir Sodium
- Gatifloxacin (EENT)
- Gentamicin (EENT)
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- Glycopyrronium
- Glycopyrronium
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- Guanfacine
- Haemophilus b Vaccine
- Hepatitis A Virus Vaccine Inactivated
- Hepatitis B Vaccine Recombinant
- Hetlioz
- Hetlioz LQ
- Homatropine
- Hydrocortisone (EENT)
- Hydrocortisone (Systemic)
- Hydroquinone
- Hylorel
- Hyperosmotic Laxatives
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- Influenza Vaccine Recombinant
- Influenza Virus Vaccine Inactivated
- Inotuzumab
- Insulin Human
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- Intermezzo
- Intuniv
- Iodoquinol (Topical)
- Iodoquinol (Topical)
- Ipratropium (EENT)
- Ipratropium (EENT)
- Ipratropium (Systemic, Oral Inhalation)
- Ismelin
- Isoproterenol
- Ivermectin (Systemic)
- Ivermectin (Topical)
- Ixazomib Citrate (Systemic)
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- Kapvay
- Ketoconazole (Systemic)
- Ketorolac (EENT)
- Ketorolac (EENT)
- Ketorolac (EENT)
- Ketorolac (EENT)
- Ketorolac (Systemic)
- Ketotifen
- Lanthanum
- Lecanemab
- Lefamulin
- Lemborexant
- Lenacapavir (Systemic)
- Leniolisib
- Letermovir
- Letermovir
- Levodopa/Carbidopa
- LevoFLOXacin (EENT)
- LevoFLOXacin (Systemic)
- L-Glutamine
- Lidocaine (Local)
- Lidocaine (Systemic)
- Linezolid
- Lofexidine
- Loncastuximab
- Lotilaner (EENT)
- Lotilaner (EENT)
- Lucemyra
- Lumasiran Sodium
- Lumryz
- Lunesta
- Mannitol
- Mannitol
- Mb-Tab
- Measles, Mumps, and Rubella Vaccine
- Mecamylamine
- Mechlorethamine
- Mechlorethamine
- Melphalan (Systemic)
- Meningococcal Groups A, C, Y, and W-135 Vaccine
- Meprobamate
- Methoxy Polyethylene Glycol-epoetin Beta (Systemic)
- Methyldopa
- Methylergonovine, Ergonovine
- MetroNIDAZOLE (Systemic)
- MetroNIDAZOLE (Systemic)
- Miltown
- Minipress
- Minocycline (EENT)
- Minocycline (Systemic)
- Minoxidil (Systemic)
- Mometasone
- Mometasone (EENT)
- Moxifloxacin (EENT)
- Moxifloxacin (Systemic)
- Nalmefene
- Naloxone (Systemic)
- Natrol Melatonin + 5-HTP
- Nebivolol Hydrochloride
- Neomycin (EENT)
- Neomycin (Systemic)
- Netarsudil Mesylate
- Nexiclon XR
- Nicotine
- Nicotine
- Nicotine
- Nilotinib (Systemic)
- Nirmatrelvir
- Nirmatrelvir
- Nitroglycerin (Systemic)
- Ofloxacin (EENT)
- Ofloxacin (Systemic)
- Oliceridine Fumarate
- Olipudase Alfa-rpcp (Systemic)
- Olopatadine
- Omadacycline (Systemic)
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- Oxacillin
- Oxymetazoline
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- Palovarotene (Systemic)
- Paraldehyde
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- Peginterferon Beta-1a (Systemic)
- Penicillin G
- Pentobarbital
- Pentosan
- Pilocarpine Hydrochloride
- Pilocarpine, Pilocarpine Hydrochloride, Pilocarpine Nitrate
- Placidyl
- Plasma Protein Fraction
- Plasminogen, Human-tmvh
- Pneumococcal Vaccine
- Polymyxin B (EENT)
- Polymyxin B (Systemic, Topical)
- PONATinib (Systemic)
- Poractant Alfa
- Posaconazole
- Potassium Supplements
- Pozelimab (Systemic)
- Pramoxine
- Prazosin
- Precedex
- Precedex injection
- PrednisoLONE (EENT)
- PrednisoLONE (Systemic)
- Progestins
- Propylhexedrine
- Protamine
- Protein C Concentrate
- Protein C Concentrate
- Prothrombin Complex Concentrate
- Pyrethrins with Piperonyl Butoxide
- Quviviq
- Ramelteon
- Relugolix, Estradiol, and Norethindrone Acetate
- Remdesivir (Systemic)
- Respiratory Syncytial Virus Vaccine, Adjuvanted (Systemic)
- RifAXIMin (Systemic)
- Roflumilast (Systemic)
- Roflumilast (Topical)
- Roflumilast (Topical)
- Rotavirus Vaccine Live Oral
- Rozanolixizumab (Systemic)
- Rozerem
- Ruxolitinib (Systemic)
- Saline Laxatives
- Selenious Acid
- Selexipag
- Selexipag
- Selpercatinib (Systemic)
- Sirolimus (Systemic)
- Sirolimus, albumin-bound
- Smallpox and Mpox Vaccine Live
- Smallpox Vaccine Live
- Sodium Chloride
- Sodium Ferric Gluconate
- Sodium Nitrite
- Sodium oxybate
- Sodium Phenylacetate and Sodium Benzoate
- Sodium Thiosulfate (Antidote) (Systemic)
- Sodium Thiosulfate (Protectant) (Systemic)
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- Suvorexant
- Tacrolimus (Systemic)
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- Tafenoquine (Krintafel)
- Talquetamab (Systemic)
- Tasimelteon
- Tedizolid
- Telotristat
- Tenex
- Terbinafine (Systemic)
- Tetrahydrozoline
- Tezacaftor and Ivacaftor
- Theophyllines
- Thrombin
- Thrombin Alfa (Recombinant) (Topical)
- Timolol (EENT)
- Timolol (Systemic)
- Tixagevimab and Cilgavimab
- Tobramycin (EENT)
- Tobramycin (Systemic)
- TraMADol (Systemic)
- Trametinib Dimethyl Sulfoxide
- Trancot
- Tremelimumab
- Tretinoin (Systemic)
- Triamcinolone (EENT)
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- Tucatinib (Systemic)
- Unisom
- Vaccinia Immune Globulin IV
- Valoctocogene Roxaparvovec
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- Varenicline (Systemic)
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- Varenicline Tartrate (EENT)
- Vecamyl
- Vitamin B12
- Vonoprazan, Clarithromycin, and Amoxicillin
- Wytensin
- Xyrem
- Xywav
- Zaleplon
- Zirconium Cyclosilicate
- Zolpidem
- Zolpidem (Oral)
- Zolpidem (Oromucosal, Sublingual)
- ZolpiMist
- Zoster Vaccine Recombinant
- 5-hydroxytryptophan, melatonin, and pyridoxine
Carane nggunakake Flurbiprofen (EENT)
Administrasi
Administrasi Oftalmik
Olesake ing mripat minangka solusi ophthalmic.
Aja kontaminasi wadhah solusi.
Dosis
Kasedhiya minangka flurbiprofen sodium; dosis ditulis ing syarat-syarat flurbiprofen sodium.
Wong diwasa
Inhibisi Intraoperative Miosis Ophthalmic1 tetes larutan 0,03% menyang mripat (s) sing nglakoni operasi wiwit 2 jam sadurunge operasi; baleni kanthi interval kira-kira 30 menit kanthi total 4 tetes saben mripat sing kena.
Pènget
Kontraindikasi
Hipersensitivitas sing dikenal kanggo flurbiprofen sodium utawa bahan apa wae ing formulasi.
Pènget/PanandhapPènget
Efek Hematologi
Bisa nyandhet agregasi platelet lan ndawakake wektu getihen.
Bisa nyebabake tambah getihen saka jaringan okular (kalebu hyphemas) nalika digunakake bebarengan karo operasi okular.
Gunakake kanthi ati-ati ing pasien kanthi kecenderungan pendarahan sing ndasari utawa ing wong sing nampa obat-obatan sing dikenal bisa nambah wektu. wektu getihen. (Deleng Obat Spesifik ing Interaksi.)
Reaksi Sensitivitas
Reaksi HipersensitivitasKamungkinan sensitivitas silang karo aspirin lan NSAIA liyane. Gunakake kanthi ati-ati ing pasien sing duwe riwayat hipersensitifitas kanggo obat kasebut (reaksi anafilaksis sing abot, meh fatal kanggo flurbiprofen lisan) lan sing asma, rhinitis, utawa urtikaria dicemplungake dening aspirin utawa NSAIA liyane.
Pancegahan Umum
Komplikasi Marasake LukaBisa alon utawa tundha penyembuhan tatu (kalebu kornea).
Efek OkularEksaserbasi keratitis herpes simpleks epitelial aktif (keratitis dendritik), konjungtivitis sing luwih abot, perforasi kornea, lan/utawa kornea awan sing dilaporake ing kewan. Gunakake kanthi ati-ati banget ing pasien karo keratitis herpes simplex epithelial aktif.
Populasi Spesifik
KandhutanKategori C.
LaktasiDistribusi menyang susu sawise administrasi sistemik; ora dingerteni manawa disebarake menyang susu sawise aplikasi topikal menyang mripat. Mungkasi nyusoni utawa obat kasebut.
Panggunaan PediatrikKaamanan lan khasiat durung ditetepake.
Panggunaan GeriatrikOra ana bedane sing signifikan babagan safety lan khasiat relatif marang wong diwasa sing luwih enom.
Efek Umum sing Sabar
Ocular stinging, burning, or discomfort and other minor symptoms of ocular iritasi (contone, sobek, rasa mata garing, nyeri mripat kusam, fotofobia); gatel; sensasi awak manca; fibrosis; miosis; lan midriasis.
Apa obatan liyane bakal mengaruhi Flurbiprofen (EENT)
Interaksi karo obat ophthalmic topikal liyane ora dievaluasi kanthi lengkap.
Obat Spesifik
Obat
Interaksi
Komentar
Asetilkolin klorida
Efek miotik suda sing dilapurake nalika digunakake karo flurbiprofen, sanajan studi klinis lan kewan anyar ora nuduhake interaksi
Anesthetics, lokal (contone, benoxinate, Capsaicin)
Efek aditif ing inhibisi miotik sajrone operasi okular sing dituduhake ing kewan
Antikoagulan
Komplikasi pendarahan sing mungkin
Gunakake kanthi ati-ati
Efek miotik suda dilaporake nalika digunakake karo flurbiprofen, sanajan studi klinis lan kewan anyar ora nuduhake interaksi
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