Homatropine
Kelas obat: Agen Antineoplastik
Panganggone Homatropine
Pemeriksaan Oftalmologis
Digunakake kanggo ngasilake midriasis lan sikloplegia kanggo refraksi. Nanging, amarga homatropine nduweni efek cycloplegic midriatik lan relatif lemah, antimuskarinik liyane bisa uga luwih disenengi.
Inflamasi Ophthalmic
Manajemen kondisi inflamasi akut (contone, iridocyclitis) saka saluran uveal.
Perioperative Mydriasis
Digunakake kanggo pre- lan postoperative states nalika mydriasis dibutuhake.
Opasitas Lensa Axial
Digunakake minangka bantuan optik ing sawetara kasus opasitas lensa aksial.
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Carane nggunakake Homatropine
Umum
Administrasi
Administrasi Ophthalmic
Aplikasi topikal ing mripat minangka solusi ophthalmic.
Mung kanggo panggunaan ophthalmic topikal. Ora kanggo injeksi.
Sawise aplikasi topikal, tekanan driji ing kantung lakrimal suwene 2-3 menit kanggo nyegah panyerepan sistemik sing berlebihan.
Aja kontaminasi wadah larutan.
Dosis
Kasedhiya minangka homatropine hydrobromide; dosis sing dituduhake ing syarat-syarat uyah.
Ing pasien kanthi irides sing akeh pigmen, dosis sing luwih dhuwur bisa uga dibutuhake.
Pasien Anak
Gunakake mung solusi 2% ing pasien pediatrik.
Pemeriksaan Oftalmologis Oftalmik1 tetes larutan 2% ing mripat sakcepete sadurunge prosedur; bisa mbaleni kanthi interval 10 menit yen perlu.
Inflamasi Ophthalmic Ophthalmic1 tetes larutan 2% ing mripat 2 utawa 3 kaping dina.
Dewasa
Pemeriksaan Oftalmologis Oftalmik1 utawa 2 tetes solusi 2 utawa 5% ing mripat sakcepete sadurunge prosedur; bisa mbaleni maneh ing 5-10 menit yen perlu.
Inflamasi Ophthalmic Ophthalmic1 utawa 2 tetes larutan 2 utawa 5% ing mripat 2 utawa 3 kaping dina utawa, yen perlu, nganti saben 3-4 jam.
Populasi Khusus
Saiki ora ana rekomendasi dosis populasi khusus.
Pènget
Kontraindikasi
Pènget/PanandhapPènget
Kahanan sing bebarengan
Pertimbangake risiko lan mupangat ing pasien sing nandhang keratoconus (homatropine bisa nyebabake pupil sing dilebarake tetep), sindrom Down, lan bocah-bocah sing ngalami karusakan otak.
Reaksi Sensitivitas
Mateni yen ana pratandha utawa gejala sensitivitas sajrone perawatan.
Pangawas Umum
Efek SistemikPenggunaan sing berlebihan, utamane ing bocah-bocah, pasien geriatrik, utawa individu liyane sing rentan, bisa nyebabake efek antimuskarinik sistemik sing ala, kalebu delirium, agitasi, lan koma. Fisostigmine parenteral minangka antidote sing disaranake kanggo gejala antikolinergik sistemik.
Populasi Spesifik
KandhutanKategori C.
LaktasiOra dingerteni manawa homatropine disebarake menyang susu. Ati-ati nalika digunakake ing wanita sing nyusoni.
Panggunaan PediatrikKeamanan lan khasiat ora ditetepake ing pasien pediatrik.
Gunakake kanthi ati-ati banget ing bayi lan bocah cilik amarga tambah kerentanan kanggo efek sistemik saka obat kasebut ing pasien kasebut. Coba risiko lan mupangat panggunaan ing bocah-bocah sing nandhang karusakan otak.
Panggunaan GeriatrikOra ana bedane signifikan ing safety utawa khasiat dibandhingake karo wong diwasa sing luwih enom.
Gunakake kanthi ati-ati amarga tambah kerentanan kanggo efek sistemik. saka obat ing pasien geriatri.
Efek Umum sing Sabar
Tinggi IOP, stinging transient, kobong. Kanthi administrasi sing berpanjangan, iritasi lokal (ditandani karo konjungtivitis folikel, kemacetan pembuluh darah, edema, eksudat, lan dermatitis eczematoid ), ngelak, tutuk garing, tambah sensitivitas cahya ing mripat.
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