Ciprofloxacin Kabi 200mg Fresenius Kabi Pengobatan infeksi, infeksi saluran kemih (100ml)

Bentuk sediaan botol
Spesifikasi Ciprofloxacin
Komposisi Fresenius Kabi Vietnam Joint Stock Company

Komposisi

Thành phần cho 100ml

Informasi komposisi	Isi
Ciprofloxacin	200 mg

Migunakake

Indikasi

Ciprofloxacin Kabin dituduhake ing kasus ing ngisor iki:

Infèksi sing disebabake dening bakteri sing sensitif marang ciprofloxacin. infèksi saluran kemih ndhuwur lan ngisor; prostatitis; inflammation balung; Peradangan usus bakteri sing abot, infeksi abot ing rumah sakit, infeksi immunodeficiency. Amarga inhibisi enzim DNA Girase, obat kasebut nyegah salinan kromosom, nyebabake bakteri ora bisa ngasilake kanthi cepet. Ciprofloxacin duweni efek apik ing bakteri antibiotik saka klompok liya (aminoglycosides, cephalosporin, tetracyclin, penicillin ...) lan dianggep minangka salah sawijining obat sing paling kuat ing klompok Fluoroquinilon.

Spektrum antibakteri: Antarane bakteri aerobik Gram (-), Ciprofloxacin bisa dadi efek in vitro, Colobacteriaceae, lan E. Entobacter, Klebsiella, Proteus, Providencia, Salmonella, Sernella, Shigella, lan Yersinia. Obat iki uga nuduhake aktivitas karo Pseudomonas Aeruginosa lan Neisseria Gonorrhoeae. H. Influenza, Moraxella Catarhalis (Branhamella Catnrhalis), lan N. Meningiftidis uga minangka galur sing sensitif. Bakteri Gram (-) aerobik liyane kacarita sensitif marang Ciprofloxacin kalebu Gardnerrella Vaginalis, Helicobacter Pylori, Legionella.

Antarane bakteri gram aerobik (+), Ciprofloxacin bisa dianggo karo staphylococci, kalebu galur penicillinase lan galur non-penicillinase aerus, lan sawetara galur staphylococci non-penicillinase (MR) aerobik. Streptococci, utamane Streptococcus Pneumonia lan Enterococci, kurang sensitif marang Ciprofloxacin. Bakteri gram (+) liyane sing sensitif marang ciprofloxacin in vitro yaiku galur Bacillus; Kanthi galur corynebacterium, aktivitas bisa uga owah.

Umume bakteri anaerob tahan ciprofloxacin, kalebu bacteroides fragilis lan Clostridium difficile.

Ciprofloxacin uga bisa digunakake karo Mycobacteria, Mycoplasma, Rickettsia, Chlamydia Trachomatis, lan Ureaplasma influenza Urealytic utamané. MRSA, PS galur. Aeruginosa, E. Coli, Klebsiella Pneumonia, C.jejuni, N. Gonorrhoeae, and Str. Pneumonia wis muncul sajrone perawatan karo ciprofloxacin, sanajan jinis tahan beda-beda gumantung saka geografi. Resistensi ciprofloxacin utamane liwat perantara kromosom, sanajan ana uga resistensi liwat perantara plasma.

Farmakokinetik dinamis

ciprofloxacin nyerep kanthi cepet, konsentrasi maksimal ing plasma sawise infus intravena sajrone 30 menit kanthi dosis 200mg yaiku 3-4 mg / liter. Separuh urip ing plasma kira-kira 3,5 nganti 4,5 jam. Obat kasebut disebarake kanthi akeh, gampang nembus menyang jaringan. Ciprofloxacin ngliwati plasenta lan diekskresi liwat susu ibu. Eliminasi ing wangun urin sing ora owah (75%) lan pupuk (15%).

Sadurunge njupuk Ciprofloxacin Kabi 200mg Fresenius Kabi Pengobatan infeksi, infeksi saluran kemih (100ml)

How to use intravenous infusion. Dosage Adults: Venous time in 60 minutes: Intractive urinary tract infections: 200mg-400mg/ time x 2 times/ day. Time/day. Venous time from 30-60 minutes For patients with renal failure: Ciprofloxacin should be reduced for patients with adult kidney failure by reducing the total daily dose and/or by increasing the distance between doses depending on the patient's creatinine (CC) clearance. Creatinine clearance (ml/minute) Dosage (intravenous transmission) Suggestions Now Patients with hemolysis or abdominal dispenser up to 400 mg every 24 hours, after the divergence Ciprofloxacin treatment time depends on the type of infection and the severity of the disease and should be determined according to the clinical response and microorganisms of the patient. For most infections, the treatment should continue at least 48 hours after the patient has no symptoms. The treatment time is usually 1-3 weeks, but with severe or complicated bacterial infections, it may be necessary to treat longer. Ciprofloxacin treatment may need to continue for 4-6 weeks or longer in bone and joint infections. Bacterial diarrhea is usually treated for 3-7 days or may be shorter. Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What do do when overdose? In case of large overdose, in addition to conventional emergency measures, renal function should be monitored, including urine pH and acidification if needed, to prevent urinary crystals. Patients should be compensated enough water and in case the kidneys are damaged by urinary minorities for too long, may need hemolysis. What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double doses to compensate for missed dose.

Efek sisih

Nalika nggunakake obat kasebut asring duwe efek sing ora dikarepake (ADR) kayata:

Umum (ADR> 1/100):

Pencernaan: Mual, muntah, diare, nyeri weteng.

Sistemik: sirah, demam obat. kimia.

Kulit: ruam, gatal, vena cethek

Badan sistemik: Anafilaksis utawa anafilaksis. Tambah tekanan intrakranial. Kulit. Ana sawetara kasus tendon rusak, utamane ing wong tuwa nalika digunakake ing kombinasi karo kortikosteroid.

Kanggo ngindhari kristal kasebut, njaga banyu ngombe sing cukup, supaya urin dadi alkalin banget.

Yen diare sing abot lan saya suwe sajrone perawatan lan sawise perawatan, pasien bisa uga nandhang kelainan usus sing abot (kolitis palsu) kudu mandhegake ciprofloxacin lan ngganti antibiotik liyane, yen ana antibiotik sing cocog. ana pratandha saka efek samping, perlu kanggo mungkasi nggunakake ciprofloxacin lan pasien kudu diobati ing fasilitas medis, sanajan efek samping kasebut biasane entheng utawa moderat lan bakal mandheg nalika mandheg ciprofloxacin.

Kabar dhokter babagan efek sing ora dikarepake nalika nggunakake obat kasebut.

Pènget

Sadurunge nggunakake obat kasebut, sampeyan kudu maca instruksi kasebut kanthi teliti lan deleng informasi ing ngisor iki.

contraindicated

Obat Ciprofloxacin contraindicated ing kasus ing ngisor iki:

Wong sing duwe riwayat hipersensitifitas marang ciprofloxacin lan obat sing gegandhengan kayata asam nalidixic lan kuinolon liyane. Aja nggunakake ciprofloxacin kanggo wanita ngandhut lan nyusoni, kajaba dipeksa digunakake.

Ati-ati nalika nggunakake

kudu ati-ati banget nalika njupuk obat kanggo pasien ing kasus ing ngisor iki:

Wong sing duwe riwayat epilepsi utawa gangguan sistem saraf pusat, gagal ati utawa fungsi ginjel, defisiensi G6DP, myasthenia gravis. Perlu ngawasi pasien lan nggawe antibiotik kanthi rutin kanggo njupuk perawatan sing cocog miturut antibiotik. Gunakake ciprofloxacin kanggo bocah cilik lan tuwa (ing eksperimen, obat-obatan sing nyebabake degenerasi tulang rawan ing sendi gravitasi).

Efek obat kasebut ing kemampuan nyopir lan ngoperasikake mesin

Obat kasebut bisa nyebabake pusing, pikiran mumet, mengaruhi kendaraan utawa mesin sing digunakake.

Gunakake obat kanggo wanita nalika meteng lan laktasi

meteng:

Digunakake ing kasus infeksi abot tanpa antibiotik liyane.

wektu nyusoni:

Aja nggunakake ciprofloxacin kanggo ibu sing nyusoni. Yen ibu kepeksa nggunakake ciprofloxacin, dheweke kudu mandheg nyusoni.

Tindakake instruksi saka dokter. Obat kasebut mung kudu digunakake nalika keuntungan ora ana risiko.

Interaksi obat 2>

fluoroquinolon, kalebu ciprofloxacin nyegah sistem enzim sitokrom P450 CYP1A2 lan bisa nambah konsentrasi serum obat sing diowahi liwat sistem enzim iki kayata clozapine, ropinirol, theophyline, lan tizanidine. Keyakinan marang Ciprofloxacin lan tizanidin bebarengan, nalika digunakake bebarengan karo theophylin kudu nyuda dosis theophylin lan ngontrol konsentrasi serum. Clozapin utawa Ropinizol bisa digunakake bebarengan karo ciprofloxacin nanging kudu ngawasi manifestasi klinis sing ana ing panyesuaian dosis yen perlu.

Ciprofloxacin wis dilaporake nambah efek perawatan obat kanggo glibenclamide oral. Hipoglisemia, kadhangkala pati ana ing pasien sing nggunakake glibenclamide bebarengan. Ciprofloxacin bisa nyandhet ekskresi ing tubulus ginjel lan nambah keracunan methotrexate.

Sawetara fluoroquinolones bisa nambah QT lan mulane ora kanggo pasien sing nggunakake obat berirama kayata Quinidine, Procainamide utawa Amiodaron lan Sotalol. Kajaba iku, ati-ati nalika digunakake bebarengan karo obatan liyane uga duwe efek iki (kayata antihistamin Astemizol lan Terfenadin, Cisapride, Erythromycin, Pentamidin, Phenothiazine utawa 3 -ring obat anti-depresi).

Panganggone obat anti-inflamasi nonsteroid kanthi konsentrasi (ibuprofen, indomethacin ...) bakal ningkatake efek samping ciprofloxacin.

Penyerapan ciprofloxacin bisa dikurangi 1⁄2 yen digunakake bebarengan sawetara siklofosfamid, vincistin, doxorubicin, cytosine, arabinoside, mitotron.

Panggunaan ciprofloxacin lan cyclosporin bebarengan bisa nyebabake peningkatan kreatinin serum. Kudu mriksa kreatinin serum kaping pindho saben minggu.

Probenecid nyuda tingkat filtrasi glomerulus lan nyuda ekskresi ing tubulus ginjal, saéngga nyuda eliminasi obat liwat urin.

warfarin ing kombinasi karo ciprofloxacin bisa nyebabake prothrombin. Perlu rutin mriksa prothrombin getih lan nyetel dosis antikoagulan.

Panyimpenan

Ninggalake papan sing adhem, aja nganti cahya, suhu ngisor 30⁰C, aja beku.

Supaya ora bisa digayuh bocah-bocah, waca instruksi kasebut kanthi teliti sadurunge digunakake.

Obat liyane

Disclaimer

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