Obat Exopan 50mg/ml Ha Nam ngobati kekurangan zat besi sing didhelikake lan anemia amarga kekurangan zat besi (30ml)

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Spesifikasi Besi (III) Hidroksid Polimaltosa

Komposisi

Thành phần cho 1ml

Informasi komposisi	Isi
Besi (III) Hidroksid Polimaltosa	50 mg

Migunakake

indikasi

Obat Exopan dituduhake ing kasus ing ngisor iki:

Mbantu nambani kekurangan zat besi lan anemia amarga kurang zat besi (kanthi kekurangan zat besi).

Pangobatan pencegahan kekurangan zat besi kanggo nyukupi rekomendasi saben dina (RDA) ing wanita ngandhut lan lactating, bocah-bocah, wong enom, wanita sing nyiapake kanggo ngandhut lan wong diwasa (kayata vegetarian lan wong tuwa).

Kekurangan zat besi bisa nyebabake gejala umum kayata tambah lemes, rasa ora nyaman, gelisah, sirah, anorexia, immunodeficiency, urtikaria, kulit garing, rambut lan kuku rapuh.

Farmakokologi

kompleks besi (III) Hydroxyd polymaltose.

Klompok farmakologi: Vitamin lan mineral/obat kanggo anemia.

Kode ATC: B03AB05.

Uyah wesi, kalebu wesi (III), hydroxyd polymaltose, nduweni peran penting ing perawatan uga nyegah anemia kekurangan zat besi. Panyimpenan wesi bisa disimpen ing bentuk feritin lan hemosiderin kanggo nggawe hemoglobin. Inti wesi (III) hidroksida wesi (III) hidroksid polimaltosa diubengi dening akeh molekul gedhe kanthi molekul kira-kira 52300 dalton, dadi gedhe nganti difusi liwat membran mukosa kurang saka 40 kali. Wesi ing inti wesi (III) hidroksid polimaltosa disambung karo struktur sing padha karo feritin. Wesi (III) Hydroxyd polymaltose beda karo wesi (II) sulfat amarga keamanan dhuwur lan keracunan rendah amarga ora ana ion wesi gratis. Iron (III) Hydroxyd Polymaltose minangka kompleks wesi (III) hidroksid sing digabungake karo polimaltosa. Wangun ionisasi ionisasi mbantu weteng kurang iritasi tinimbang uyah wesi konvensional, mbantu pasien ngejarke luwih apik, titik sing penting banget kanggo perawatan jangka panjang anemia kekurangan zat besi kanthi persiapan sing ngemot wesi. Efektivitas wesi (III) hidroksid polimaltosa kanggo nyegah lan ngobati anemia kekurangan zat besi wis kabukten ing uji klinis.

Nilai hemoglobin mundhak luwih cepet nalika nggunakake wesi (III) Hydroxyd polymaltose dibandhingake karo uyah wesi konvensional. Nalika nggunakake wesi (III) hydroxyd polymaltose wis katon nilai hemoglobin mundhak kanggo 0,8 mg / dl saben minggu. Kajaba iku, ana peningkatan sing luwih cepet tinimbang hematokrit, MCV, serum lan feritin.

Kekurangan zat besi bisa nyebabake gejala umum kayata tambah lemes, rasa ora nyaman, gelisah, sirah, anorexia, immunodeficiency, urtikaria, kulit garing, rambut lan kuku rapuh.

Farmakokinetik dinamis

Penyerapan ion wesi (III) saka proses hidroksid besi (III) yaiku hidroksid besi (III). Nalika kompleks wesi (III) Hydroxyd Polymaltose kapapar kohesi wesi ing permukaan mukosa, bakal ngeculake ion wesi (III) lan aktif diangkut menyang sel mukosa amarga protein pembawa lan banjur disambungake menyang ferritin utawa transfer. Protein pembawa kalebu mucin, intergrin lan mobilferrin. Wesi dibebasake saka protein pembawa lan disimpen ing sel mukosa ing wangun feritin utawa digawa dening protein pembawa lan dibebasake kanggo gabung karo Transferring.

Bioavailabilitas kompleks wesi (III) Hydroxyd polymaltose padha karo uyah wesi II ing kewan eksperimen lan ing manungsa ing sintesis hemoglobin. Bioavailabilitas wesi (III) hydroxyd polymaltose nalika dijupuk ora kena pengaruh bahan pangan kayata asam fitat, asam oksalat, tanin, uyah kolin natrium alginat, vitamin A, D3, E, lenga kedelai lan glepung, ora kaya uyah wesi konvensional. Wesi ing kompleks wesi (III) Hydroxyd polymaltose mlebu

Sadurunge njupuk Obat Exopan 50mg/ml Ha Nam ngobati kekurangan zat besi sing didhelikake lan anemia amarga kekurangan zat besi (30ml)

How to use Drugs in the form of solution, oral use. Turn the bottle upside down so that the drug is out in drops. Gently touch the bottle to drop. Do not shake the bottle. Should drink in or immediately after eating. Exopan can be used with fruit juice, vegetable juice or food. Light color change does not affect product quality. Dosage daily dose can be divided into small or disposable doses. Dosage and treatment time depend on the degree of iron deficiency or as directed by the doctor for each specific case. iron deficiency anemia (with iron deficiency): Treatment for about 3-5 months until the value of hemoglobin returns to normal, then it is necessary to continue treatment for a few weeks with the indications for the potential iron deficiency to supplement the amount of iron reserves. Hidden iron deficiency: Treatment for about 1-2 months. iron deficiency anemia (with iron deficiency) Potential iron deficiency (25 - 50 mg iron) 6 - 10 drops/day (15 - 25 mg iron) 2 - 4 drops/day (5 - 10 mg iron) children (1-12 years) (50 - 100 mg iron) 10 - 20 drops/day (25 - 50 mg iron) 4 - 6 drops/day (10 - 15 mg iron) (100 - 300 mg iron) 20 - 40 drops/day (50 - 100 mg iron) 4 - 6 drops/day (10 - 15 mg iron) (200 - 300 mg iron) 40 drops/day (100 mg iron) 20 - 40 drops/day (50 - 100 mg iron) premature babies 1-2 drops/kg daily in 3-5 months (2.5-5 mg of iron) Each 1 ml corresponds to 20 drops ~ 50 mg iron. Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist. What to do when using overdose? Exopan is generally safe. Studies comparing iron (II) sulfate and iron (III) Hydroxyd polymaltose on mice also identify the LD50 of iron (II) sulfate as 350 mg/kg, but there is no disease or death in the group using iron (III) hydroxide polymaltose in doses of over 1000 mg/kg. The iron absorption of iron (III) Hydroxyd polymaltose is less than iron (III) Hydroxyd Polymaltose has better tolerance with digestive tract, along with the safety of iron (III) higher hydroxide polymaltose, which may have an important significant to reduce the risk of iron overdose. Although iron (III) Hydroxyd polymaltose is safer than iron salts (II) inorganic, can still overdose but rare. Symptoms of iron overdose include fatigue, nausea, vomiting, abdominal pain, stools such as darkness, fast and weak pulse, fever, coma, convulsions and death. Need emergency immediately if iron overdose. In an emergency, call the 115 emergency center immediately or go to the nearest local health station. What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Efek sisih

Nalika nggunakake ExoPan sampeyan bisa ngalami efek sing ora dikarepake (ADR) kayata:

Istilah ing ngisor iki digunakake kanggo nggolongake reaksi salabetipun adhedhasar frekuensi:

Umum banget: ≥ 1/10;

Umum: ≥ 1/100 lan

Sistem kekebalan

Jarang banget: reaksi alergi.

Gangguan pencernaan:

Umume banget: owah-owahan warna feces.

Kurang: gatel, ruam.

Gangguan sistem saraf:

Kurang: sirah.

Takon dokter babagan efek sing ora dikarepake nalika nggunakake obat kasebut.

Pènget

Sadurunge nggunakake obat kasebut, sampeyan kudu maca instruksi kasebut kanthi teliti lan deleng informasi ing ngisor iki.

contraindicated

anti-contraindications ing kasus ing ngisor iki:

Hipersensitivitas kanggo komponen obat apa wae.

Ati-ati nalika nggunakake

kudu ati-ati banget nalika njupuk obat kanggo pasien ing kasus ing ngisor iki:

Overdosis obat-obatan sing ngandhut wesi bisa nyebabake keracunan sing nyebabake pati ing bocah-bocah ing umur 6 taun. Sanajan Exopan cukup aman amarga wesi (III) Hydroxyd Polymaltose nduweni LD50 sing dhuwur banget, kudu ditinggalake kanggo obat kasebut ing jangkauan bocah. Yen sampeyan ora sengaja overdosis, langsung hubungi dhokter utawa pusat anti-beracun.

Obat sing ngandhut wesi, kalebu wesi (III), hidroksid polymaltose, bisa nyebabake reaksi alergi utawa anafilaksis. Yen ana reaksi alergi, langsung mandheg nggunakake Exopan lan tindakake langkah darurat.

Aja overdosis dituduhake. Perawatan anemia kudu ngetutake instruksi lan ngawasi dhokter. Kadhangkala rasa ora nyaman ing saluran pencernaan (kayata mual), bisa dikurangi kanthi njupuk obat nalika mangan. Obat wesi bisa nyebabake konstipasi utawa diare.

Ati-ati nalika digunakake kanggo wong sing alergi, gagal ati utawa gagal ginjel.

Ati-ati nalika digunakake kanggo pecandu alkohol lan wong sing nandhang penyakit gastrointestinal kayata ulkus gastrointestinal, kolitis.

Preparasi sing ngemot Sakarosa, Ati-ati kanggo pasien sing duwe genetik langka babagan intoleransi fruktosa, malabsorpsi glukosa-Galaktosa.

Efek obat kasebut ing nyopir lan mesin operasi

Obat kasebut ora mengaruhi kemampuan nyopir lan ngoperasikake mesin.

Gunakake obat kanggo wanita nalika meteng lan lactation

Produk kasebut dituduhake kanggo wanita ngandhut lan lactating yen ana risiko kekurangan zat besi.

Interaksi obat

Panliten babagan tikus sing berinteraksi karo tetracyclin, aluminium hydroxyd, acetylsalicy, sulfasalazine, kalsium karbonat, kalsium asetat, kalsium fosfat kanthi kombinasi karo vitamin D3, bromazepam, magnesium aspartate, d-penicillinamine, methyldopa, methyldopa, is methyl notdopa Paracetamol.

Semono uga, ora ana interaksi antara kompleks besi (III) Hydroxyd polymaltose karo bahan kayata asam fitat, asam oksalat, tanin, natrium alginat, kolin lan uyah, vitamin A, vitamin D3, vitamin E, minyak kedelai, glepung kacang kedelai. Bisa langsung digunakake sawise mangan.

Interaksi antarane wesi (III) Hydroxyd polymaltose lan tetracyclin utawa aluminium hydroxyd diteliti ing 3 studi ing manungsa (cross-design, 22 pasien saben sinau). Ora ana penurunan sing signifikan ing penyerapan tetracycline. Konsentrasi tetracycline ing plasma ora mundhak banget kanthi efektif. Penyerapan wesi saka kompleks wesi (III) Hydroxyd polymaltose ora suda nalika digunakake karo tetracyclin utawa aluminium hydroxyd. Mula, kompleks besi (III) Hydroxyd polymaltose bisa digunakake karo tetracyclin utawa aluminium hydroxyd.

Nggabungake preparat wesi lan preparat wesi lisan ora dianjurake, amarga nyuda panyerepan preparat wesi lisan. Mung nggunakake preparat wesi suntik yen digunakake ora efisien.

Panyimpenan

Ninggalake papan sing adhem, aja nganti cahya, suhu ngisor 30⁰C.

Supaya ora bisa digayuh bocah, waca manual pangguna kanthi teliti sadurunge digunakake.

Obat liyane

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