Obat Ha Tay Terpincold nyuda batuk garing lan batuk amarga gatel gulu (6 blister x 15 tablet)

Bentuk sediaan Kothak 6 blister x 15 tablet
Spesifikasi Terpin hidrat, kodein

Komposisi

Informasi komposisi	Isi
Terpin Hydrate	100 mg
Kodein	15 mg

Migunakake

indikasi

Obat Terpinco dituduhake ing kasus ing ngisor iki:

Ngurangi batuk garing lan watuk amarga gatel gulu ing wong diwasa.

Kodein duweni efek nyuda amarga efek langsung ing tengah watuk ing otak, Codeine ngetokake sekresi ambegan lan nambah kemiringan sekresi bronkial. Codeine ora cukup kanggo nyuda batuk. Kodein minangka obat watuk yen batuk garing.

Mekanisme tumindak kombinasi nyuda batuk lan kahak sing ora jelas.

Farmakokinetik dinamis

kodeine

panyerepan: Penyerapan apik liwat saluran pencernaan. Sawise ngombe, konsentrasi puncak Codeine ing getih diraih sawise 1 jam.

Distribusi: liwat plasenta lan distribusi menyang ASI.

Metabolisme: Kodein dimetabolisme ing ati kanthi ngurangi metil (ing posisi O-lan N-metil ing molekul) dadi morfin, norforfin lan hidrokodon. Transformasi dadi morfin ora langsung dipengaruhi dening Cytochrom P450 Isoenzyme CYP2D6 lan efek iki beda banget amarga efek saka struktur gen.

Eliminasi: Eliminasi setengah umur yaiku 3-4 jam sawise ngombe. Kodein lan produk metabolik diekskresikan utamane liwat ginjel lan menyang urin ing bentuk urin kanthi bentuk asam glukuronat.

terpin hidrat

Obat kasebut diserep kanthi apik liwat saluran pencernaan.

Sadurunge njupuk Obat Ha Tay Terpincold nyuda batuk garing lan batuk amarga gatel gulu (6 blister x 15 tablet)

Cara nggunakake

tablet lisan. Bisa ngombe nalika luwe utawa kenyang. Njupuk tablet nganggo segelas banyu.

Dosis

Wong diwasa: 1 - 2 tablet, saben 6 jam yen perlu, ora luwih saka 8 tablet / dina.

Wong tuwa utawa wong sing gagal ati: Wong diwasa setengah dosis.

Cathetan: Dosis ing ndhuwur mung kanggo referensi. Dosis spesifik gumantung saka kahanan lan tingkat kemajuan penyakit kasebut. Kanggo dosis sing cocog, sampeyan kudu takon dhokter utawa spesialis medis.

Apa sing kudu ditindakake nalika overdosis?

Tandha ing bocah-bocah (ambang beracun: 2 mg/kg kodeine dosis tunggal): nyuda ambegan, konvulsi, edema rai, ruam urtikaria, retensi urin.

Overdosis: Dhukungan pernapasan, injeksi intravena Naloxon ing kasus sing abot.

Ing kahanan darurat, langsung nelpon puskesmas 115 utawa menyang puskesmas sing paling cedhak.

Apa sing kudu ditindakake yen sampeyan lali 1 dosis? Nanging, yen wektu kanggo ngendhokke karo dosis sabanjuré cendhak banget, skip dosis lan terus tanggalan tamba. Aja nggunakake dosis kaping pindho kanggo ngimbangi dosis sing ora kejawab.

Efek sisih

Nalika nggunakake obat kasebut, ana efek sing ora dikarepake (ADR) kayata:

Obat kasebut bisa nyebabake konstipasi, ngantuk, pusing, mual, mutahke.

Pasien kudu diawasi kanthi teliti lan yen ana tandha-tandha ora normal, kudu langsung mandheg.

Yen ana efek sing ora dikarepake saka obat kasebut dadi serius, utawa efek sing ora dikarepake ora kasebut ing ndhuwur, hubungi dhokter utawa apoteker sampeyan.

Pènget

Before using the drug you need to read the instructions carefully and refer to the information below. Contraindicated Terpinco drugs contraindicated in the following cases: allergies to any ingredients of the drug. Morphin (buprenorphin, nalbuphin, pentazocin). Be cautious when using need to be very careful when taking the drug for patients in the following cases: Do not use cough treatment with phlegm. In case of not decreasing symptoms, do not increase the dose but need to re -evaluate the condition. For sports athletes. Metabolic through CYP2D6 Codeine is converted into morphine (active metabolites) through the enzyme near CYP2D6 in the liver. If part or all of this enzyme is deficient, the patient will not achieve appropriate treatment effect. It is estimated that up to 7% of the white population may lack this enzyme. However, if the patient has a strong or super -fast metabolic gene, the risk of harmful reactions caused by opioid poisoning even in the common prescription dose. These patients have the ability to convert codeine into morphine faster, leading to higher serum morphine levels than expected. The common symptoms of Opioid poisoning include consciousness, drowsiness, shallow breathing, pupils, nausea, vomiting, constipation and anorexia. In serious cases, symptoms of circulatory and respiratory decline may appear, being life -threatening and very dangerous when causing death. The estimated ratio of people carrying drug metabolism via CYP2D6 super fast in different races is summarized in the table below: racial ratio percentage% Á 1.2%to 2% Europe 1% to 2% Codeine is not recommended for use in children with respiratory function, including neuromuscular disorders, severe heart or respiratory diseases, upper and lung respiratory infections, multiple trauma or have just undergone major surgery. These factors can worsen the symptoms of Morphin poisoning. Colonel: In the composition of the drug containing nipagin (0.04mg/tablet), Nipasol (0.02mg/tablet) can cause sensitive reactions to some people, so it should be cautious with patients with atopic allergies to this component. The effect of the drug on the ability to drive and operate machinery Drugs that cause drowsiness, so it can affect the ability to drive and operate machinery. Use drugs for women during pregnancy and lactation Pregnancy Do not use. codeine: The first 3 months of pregnancy: Animal studies have shown the teratogenic effect of Codeine. In clinical studies, the research results in a small number of pregnant women seem to have excluded the monster effect of Codein. Terpin: Clinically, terpin spend has the effect of malformation in infants. However, this research has not excluded the risks. Therefore, to prevent the risk of this drug should not be used during pregnancy. Breastfeeding period Contraindications. Codeine secretion into breast milk; Some cases of reduced respiratory energy and respiratory failure in breastfed babies after drug treatment containing codeine have been described. Drug interaction drug interactions can affect the activity of the drug or cause side effects. Patients should notify the doctor or pharmacist a list of the drugs and functional foods you are using. Do not use or increase or decrease the dose of the drug without the guidance of a doctor. Morphin -operating owner (buprenorphin, nalbuphin, pentazocin): reduce the effectiveness of Codeine by blocking the competition of receptors, and increasing the risk of detox syndrome. Avoid drinking alcoholic and alcoholic beverages containing alcohol.

Panyimpenan

Simpen obat ing kothak sing ditutup, adoh saka bocah-bocah. Simpen obat ing suhu kamar, panggonan sing garing, aja nganti cahya langsung, suhu ngisor 30C.

Obat liyane

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