Obat Stella Neuronstad 300mg ndhukung epilepsi lokal (10 lepuh x 10 tablet)

Bentuk sediaan Kothak 10 blister x 10 tablet
Spesifikasi Gabapentin

Komposisi

Informasi komposisi	Isi
Gabapentin	300 mg

Migunakake

indikasi

Obat Neuronstad dituduhake ing kasus ing ngisor iki:

Ndhukung perawatan ing epilepsi lokal.

Kode ATC: N03AX12.

Gabapentin minangka obat anti-epilepsi, mekanismene ora jelas. Ing kewan uji, obat kasebut duwe efek anti-regangan sawise kejut listrik lan uga nyegah kejang sing disebabake dening pentylenetetrazol. Struktur kimia Gabapentin padha karo inhibitor neurotransmitter, asam gamma-aminobutyric (GABA), nanging Gabapentin ora langsung mengaruhi reseptor GABA, ora ngganti struktur, release, metabolisme lan pemugaran saka GABA.

farmakokinetik

gabapentin diserap liwat saluran gastrointestinal kanthi mekanisme jenuh (nalika dosis mundhak, bioavailability mudhun). Obat kasebut tekan konsentrasi puncak ing plasma sawise ngombe 2 jam lan tekan konsentrasi stabil sawise 1-2 dina. Konsentrasi serum efektif obat kasebut durung ditemtokake. Nanging, ing panaliten, jumlah konvulsi mung suda ing wong kanthi tingkat serum gabapentin saben mg / liter (11,7 micromol / liter). Konsentrasi Gabapentin plasma biasane ana ing antarane 2 mg/liter nganti 20 mg/liter.

Biokimia kira-kira 60% nalika digunakake ing dosis 1,8 g / 24 jam lan ora cocog karo dosis, lan nalika dosis mundhak luwih saka 1,8 g / 24 jam, bioavailability mudhun (bioavailability kira-kira 35% nalika digunakake ing dosis 4,8 g / 24 jam). Panganan kurang mengaruhi kacepetan lan tingkat panyerepan. Ing pasien tuwa lan pasien kanthi fungsi ginjel cacat, reresik gabapentin plasma dikurangi. Gabapentin bisa diilangi saka plasma kanthi hemolisis, mula panyesuaian dosis kanggo pasien kasebut dibutuhake.

gabapentin disebarake ing kabeh awak, menyang susu ibu, disambungake karo protein plasma sing sithik banget (

Gabapentin meh ora ana metabolisme ing awak lan diekskresi utamane liwat ginjel kanthi bentuk konstan. Wektu adol sampah Gabapentin kira-kira 5 nganti 7 jam kanggo wong sing fungsi ginjel normal.

Sadurunge njupuk Obat Stella Neuronstad 300mg ndhukung epilepsi lokal (10 lepuh x 10 tablet)

How to use Neuronstad oral oral medication, the time to take the drug does not depend on the meal. Neuronstad is used as a secondary drug to coordinate with other anti -epileptic drugs. Single use may not work. Dosage anti -epileptic Adults and children over 12 years: The first day: 300 mg x 1 time. Monday: 300 mg/time x 2 times. Maximum not exceeding 2400 mg/day. Should divide the total daily dose for each drug and the medication distance should not exceed 12 hours. When using high doses can be divided 4 times/day. For patients with impaired kidney function and hemolysis must reduce the dose; The appropriate dose needs to be adjusted according to creatinine clearance, recommended as follows: Creatinine clearance (ml/minute) Dosage The time 15 - 29 300 mg/day, divided 3 times The loading dose is 300 - 400 mg for the first person to use gabapentin, then 200 - 300 mg after every 4 hours of hemolysis. Children from 6 to 12 years old, weighing from 30 - 36 kg: First day: 300 mg x 1 time/day. Monday: 300 mg x 1 time/day. Add daily, extending the added time (up to weekly) more appropriate. There is no evaluation of the use of gabapentin for children under 12 years old with renal function. Treatment of pain caused by peripheral nerves, shingles after shingles Adults: Take no more than 1800 mg/day, divided 3 times. Or use as follows: The first day: 300 mg. Monday: 300 mg/time, 2 times a day. Elderly: Need to adjust the dose due to reduced kidney function. Specific dose depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose? Most cases of overdose recover after using supportive treatment. There may be drugs from the body by hemolysis. In an emergency, call the 115 emergency center immediately or go to the nearest local health station. What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Efek sisih

Gabapentin toleransi kanthi apik. Efek sisih biasane entheng utawa medium lan cenderung suda nalika perawatan terus. Efek samping sing paling umum kanggo syaraf lan asring nyebabake mandheg.

Umum (1/100 ≤ ADR

Neurologis: Mobilitas kelangan koordinasi, geter bola mata, lemes, pusing, edema, ngantuk, ilang memori. mili. Virus.

Neurologis: Kelangan memori, kelangan basa, depresi, jengkel, temperamen utawa owah-owahan mental, lumpuh entheng, suda utawa ilang sensori, sirah. kanggo.

Langka (1/10.000 ≤ ADR Neurologis: Kelumpuhan neurologis, kelainan pribadine, tambah sensitivitas, kurang olahraga, gangguan mental. Mripat: mripat gatel, mripate berair, retinopati, iritis Nalika nggunakake obat.

Pènget

Sadurunge nggunakake obat kasebut, sampeyan kudu maca instruksi kasebut kanthi teliti lan deleng informasi ing ngisor iki.

contraindicated

Obat Neuronstad contraindicated ing kasus ing ngisor iki:

Hipersensitifitas kanggo Gabapentin utawa bahan obat kasebut.

Ati-ati nalika nggunakake

Gunakake kanthi ati-ati kanggo wong sing duwe riwayat kelainan mental, fungsi ginjel cacat lan hemolisis, operator mobil utawa mesin.

Obat kasebut bisa nyebabake positif palsu nalika nguji proteinuria ing pasien sing nggunakake gabapentin.

Efek sing ora dikarepake biasane entheng utawa medium lan cenderung suda sajrone 2 minggu perawatan terus.

Mobilisasi mundhut koordinasi gegandhengan karo dosis. Yen dosis dikurangi tanpa mbantu, obat kasebut kudu mandheg.

Yen ana sing dicurigai sindrom Stevens-Johnson, obat kasebut kudu mandheg.

Aja ndadak mandhegake obat amarga bisa nambah frekuensi kejang. Sadurunge mungkasi obat kasebut utawa ngalih menyang obat anti-epilepsi liyane, dosis kudu dikurangi alon-alon sajrone 7 dina.

Efek obat kasebut ing nyopir lan ngoperasikake mesin

gabapentin bisa uga duwe pengaruh sing sithik utawa medium ing kemampuan nyopir lan ngoperasikake mesin. Gabapentin tumindak ing sistem saraf pusat lan bisa nyebabake rasa ngantuk, pusing utawa gejala liyane sing padha. Sanajan efek ing ndhuwur mung entheng lan medium, bisa dadi bebaya potensial kanggo nyopir pasien utawa mesin operasi. Iki utamané bener ing wiwitan perawatan lan sawise nambah dosis.

Gunakake obat kanggo wanita nalika meteng lan laktasi

Wanita ngandhut

gabapentin nyebabake teratogenisitas ing tikus. Ora ana riset sing nyukupi lan dikontrol babagan wanita ngandhut. Nanging, mung obat kanggo wanita ngandhut yen pancene perlu lan duwe pertimbangan sing luwih dhuwur babagan keuntungan tinimbang risiko kanggo janin.

wanita sing nyusoni

Yen dijupuk kanthi lisan, gabapentin entuk ASI. Efek obat kasebut ing bayi isih durung dingerteni, mula mung gabapentin kanggo wanita sing nyusoni sing bener-bener perlu lan kanthi ati-ati nimbang keuntungan sing luwih dhuwur tinimbang risiko resiko.

Interaksi obat

Yen digunakake bebarengan, Gabapentin ora ngganti farmakokinetik obat anti-epileptik liyane kayata carbamazepin, phenybital, valzepamicbital, valpropamicbital. Antacid Gabapentin nyuda bioavailabilitas udakara 20% amarga panyerepan obat kasebut. Gabapentin kudu digunakake sawise paling ora 2 jam antacid.

Tyeum obat

Amarga ora ana studi babagan korélasi obat kasebut, mula ora nyampur obat iki karo obat liya.

Panyimpenan

Simpen ing suhu ora ngluwihi 30 ° C ing kemasan asli, aja nganti lembab lan aja nganti cahya.

Obat liyane

Disclaimer

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