Perawatan Tafuito tipharco kanggo patologi weteng (3 blister x 10 tablet)

Bentuk sediaan Kothak 3 blister x 10 tablet
Spesifikasi Itopriide

Komposisi

Informasi komposisi	Isi
Itopriide	50 mg

Migunakake

Indications tafuito indicated treatment of stomach and intestines caused by chronic gastritis (abdominal distention, upper abdominal pain, anorexia, heartburn, nausea and vomiting). Pharmacokology Mechanism of action Itoprid hydrochloride increases the release of acetylcholin (ACH) due to the antagonistic effect of 9 D2 dopamine receptors, and inhibits the decomposition of acetylcholin released through the superiority of acetylcholinesterase, leading to increased gastric motivation. Increases stomach and intestinal motility Increases the stomach peristalsis ITOPRIDY HYDROCLORID, which increases the gastrointestinal motility of the dog at the time of awakening, depending on the bureaucracy. Itoprid hydrochloride inhibits vomit in dogs caused by apomorphin, this effect depends on the dose. Dynamic pharmacokinetics Serum concentration Serum concentration and pharmacokinetics parameters in healthy adults, after a single dose of oral 50mg otoprid hydrochloride at hunger are specified in Table 1. Table 1: Dynamic parameters Dosage cmax (μg/ml) TMAX (HR) AUC0 -∞ (μg.HR/ml) t1/2β (hour) 50 0.58 ± 0.08 0.75 ± 0.05 5.77 ± 0.33 distribution Results obtained from animal experiments: The maximum concentration is achieved in almost all tissues from 1 to 2 hours after the single dose of 5 mg/kg chitopridhydrolloride in the rat, and 2 hours after drinking high concentrations in the kidneys, small intestine, liver, adrenal gland, stomach (according to the degree of decrease from high to low) and the part of the medication goes into the central nervous system, such as brain and spinal cord, very little. When putting "c-itoprid hydrochloride at a dose of 5 mg/kg into the duodenum for rats, radioactive activity concentration in stomach muscles is about 2 times higher than blood levels. Milk excretion: When taking oral dose of 5 mg/kg C- Itoprid hydrochloride for rats, radioactive activity in milk compared to serum is 1.2 times higher in cmax, 2.6 times higher inauc, and 2.1 times higher in t metabolism and elimination At the single dose of 100mg ITOPRID HYDROCLORID for healthy adults (6 men) when hungry, the rate of excretion through water pepper within 24 hours after the highest drink is the form of N-Oxide [67.54% of the dose (89.41% of the secretion in urine)] and then the form of constant drug (4.14%), and the remaining substances are not significant. In experiments using Microsome indicating CYP or Flavin Monooxygenase (FMO), showing that FM01 and FMO3 are involved in creating N-Oxide main metabolites. However, there is no n -oxygenase activity of CYP1A2, -2A6, -2B6, -2C8, -2C9, 2C19, 2D6, 2E1, or 3A4. Other issues Serum protein bonding ratio: The ratio of serum protein bonds is 96% after using a single dose of oral 100 mg of iToprid hydrochloride for healthy people (6 men) when hungry.

Sadurunge njupuk Perawatan Tafuito tipharco kanggo patologi weteng (3 blister x 10 tablet)

Cara nggunakake

tablet tafuito kanggo lisan, ngombe sadurunge mangan.

Dosis

Dosis oral sing biasa kanggo wong diwasa yaiku 150mg iToprid hydrochloride 3 kapsul saben dina, dibagi 3 kaping, 1 tablet saben wektu.

Dosis iki bisa dikurangi gumantung saka umur lan kondisi saben pasien.

Cathetan: Dosis ing ndhuwur mung kanggo referensi. Dosis spesifik gumantung saka kahanan lan tingkat kemajuan penyakit kasebut. Kanggo dosis sing cocog, sampeyan kudu takon dhokter utawa spesialis medis.Apa sing kudu ditindakake nalika nggunakake overdosis?

Apa sing kudu ditindakake yen sampeyan lali 1 dosis? Nanging, yen wektu kanggo ngendhokke karo dosis sabanjuré cendhak banget, skip dosis lan terus tanggalan tamba. Aja nggunakake dosis kaping pindho kanggo ngimbangi dosis sing ora kejawab.

Efek sisih

Nalika nggunakake Tafuito asring duwe efek sing ora dikarepake (ADR).

SHOCK AND HIRTHDAY: SHOCK AND HIRTHDAY RESPONSIBILITY bisa uga katon, lan kudu ngawasi pasien kanthi rapet. Yen sampeyan ndeleng tandha-tandha reaksi kejut lan hipersensitivitas, kayata hipotensi, sesak ambegan, edema laring, urtikaria, pucet lan kringet ..., kudu langsung mandheg lan njupuk perawatan sing cocog.

Kelainan ati lan jaundice: kelainan ati lan jaundice bebarengan karo AST (GOT), ALT (GPT) lan Y-AGP ... bisa uga katon lan pasien kudu dipantau kanthi teliti. Yen gejala ora normal ing ndhuwur dideteksi, kudu langsung mandheg lan entuk perawatan sing cocog.

Umum

diare, konstipasi, nyeri abdomen.

gemeter, nambah prolaktin, trombosit, leukopenia.

ruam, abang, gatel, nggedhekake payudara ing wong lanang.

Pènget

Sadurunge nggunakake obat sampeyan kudu maca instruksi kasebut kanthi teliti lan deleng informasi ing ngisor iki.

contraindicated

tafuito contraindicated ing kasus ing ngisor iki:

Pasien sing duwe riwayat hipersensitifitas marang bahan apa wae obat kasebut.

Ati-ati nalika nggunakake

kudu digatekake nalika digunakake amarga obat iki nambah kegiatan asetilkolin.

Ora bisa digunakake kanggo wektu sing suwe yen ora ana perbaikan ing gejala weteng - usus.

Amarga fungsi fisiologis ing wong tuwa mudhun, reaksi salabetipun luwih kerep kedadeyan. Mula, pasien tuwa sing nggunakake obat iki kudu dipantau kanthi ati-ati, yen ana reaksi sing ora dikarepake, kudu nggunakake langkah-langkah manajemen sing cocog, kayata nyuda dosis utawa mungkasi obat kasebut.

Keamanan obat kanggo bocah-bocah durung ditemtokake.

Nggunakake obat kanggo wanita ngandhut lan lactating

Obat iki mung kudu digunakake ing wanita ngandhut, utawa ing wanita bisa ngandhut mung yen keuntungan terapi sing dikarepake luwih gedhe tinimbang risiko sing bisa ditemoni (keamanan produk iki kanggo wanita ngandhut durung diidentifikasi).

Efek obat kanggo nyopir lan ngoperasikake mesin

obat sing ora nyebabake sirah, pusing kudu digunakake kanggo driver lan operasi mesin.

Interaksi obat

kudu dicathet nalika nggunakake kombinasi Toprid hidroklorida karo anti-antasida: Tiquizium Bromide, Scopolamine Butyl Bromide, TimePidium Bromide, ...

Gejala: bisa nyuda efek nambah motilitas lambung lan usus saka Itoprid (efek kolinergik).

Mekanisme: Efek nyandhet obat anti-kolinergik bisa duwe efek farmakologis marang efek itoPrid.

Panyimpenan

Ninggalake papan sing adhem, aja nganti cahya, suhu ngisor 30⁰C.

Supaya adoh saka bocah-bocah.

Obat liyane

Disclaimer

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