Aminoglycosides

What are Aminoglycosides?

Aminoglycosides are a class of antibiotics used mainly in the treatment of aerobic gram-negative bacilli infections, although they are also effective against other bacteria including Staphylococci and Mycobacterium tuberculosis. They are often used in combination with other antibiotics.

Aminoglycosides are thought to work by inhibiting protein synthesis inside bacteria. Kill rates of bacteria are increased when higher concentrations of aminoglycosides are present; however, the margin between a safe and a toxic dose is narrow and monitoring is often needed, although once daily dosing increases the safety window. Impairment of kidney function and hearing loss are the most common side effects of aminoglycosides. Aminoglycosides tend to be used when other less toxic antibiotics are contraindicated or ineffective.

Aminoglycosides are not well absorbed when given by mouth, so need to be given by injection by healthcare personnel.

List drug with Aminoglycosides

Drug Name
Amikacin
Generic name: Amikacin
Amikacin liposome
Generic name: Amikacin Liposome
Amikin
Generic name: Amikacin
Amikin Pediatric
Generic name: Amikacin
Arikayce
Generic name: Amikacin Liposome
Garamycin
Generic name: Gentamicin
Garamycin (Gentamicin Injection)
Generic name: Gentamicin
Gentamicin
Generic name: Gentamicin
Gentamicin (Injection)
Generic name: Gentamicin
Kanamycin
Generic name: Kanamycin
Kantrex
Generic name: Kanamycin
Neo-Fradin
Generic name: Neomycin
Neomycin
Generic name: Neomycin
Neomycin (Oral)
Generic name: Neomycin
Plazomicin
Generic name: Plazomicin
Zemdri
Generic name: Plazomicin

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