Antimetabolites

What are Antimetabolites?

Antimetabolites are drugs that interfere with one or more enzymes or their reactions that are necessary for DNA synthesis. They affect DNA synthesis by acting as a substitute to the actual metabolites that would be used in the normal metabolism (for example antifolates interfere with the use of folic acid).

Antimetabolites are drugs used in cancer chemotherapy. Cancer cells divide more rapidly compared to normal cells so antimetabolites affect cancer cell replication more than they affect normal cell replication.

List drug with Antimetabolites

Drug Name
Adrucil
Generic name: Fluorouracil
Adrucil injection
Generic name: Fluorouracil (injection)
Alimta
Generic name: Pemetrexed
Arranon
Generic name: Nelarabine
Clofarabine
Generic name: Clofarabine
Clolar
Generic name: Clofarabine
Cytarabine
Generic name: Cytarabine
Cytarabine liposome
Generic name: Cytarabine Liposome
Mylocel
Generic name: Hydroxyurea
Capecitabine
Generic name: Capecitabine
Cladribine
Generic name: Cladribine (oral)
Cladribine (Intravenous)
Generic name: Cladribine
Cladribine (Oral)
Generic name: Cladribine
Cladribine injection
Generic name: Cladribine (injection)
Dacogen
Generic name: Decitabine
Decitabine
Generic name: Decitabine
Depocyt
Generic name: Cytarabine Liposome
Droxia
Generic name: Hydroxyurea
Floxuridine
Generic name: Floxuridine
Fludarabine (Intravenous)
Generic name: Fludarabine
Fludarabine (Oral)
Generic name: Fludarabine
Fludarabine injection
Generic name: Fludarabine (injection)
Fluorouracil (Intravenous, Injection)
Generic name: Fluorouracil
Fluorouracil injection
Generic name: Fluorouracil (injection)
Folotyn
Generic name: Pralatrexate
FUDR
Generic name: Floxuridine
Gemcitabine
Generic name: Gemcitabine
Gemzar
Generic name: Gemcitabine
Hydrea
Generic name: Hydroxyurea
Hydroxyurea
Generic name: Hydroxyurea
Infugem
Generic name: Gemcitabine
Leustatin
Generic name: Cladribine
Leustatin injection
Generic name: Cladribine (injection)
Mavenclad
Generic name: Cladribine (oral)
Mercaptopurine
Generic name: Mercaptopurine
Nelarabine
Generic name: Nelarabine
Oforta
Generic name: Fludarabine (oral)
Pemetrexed
Generic name: Pemetrexed
Pemfexy
Generic name: Pemetrexed
Pralatrexate
Generic name: Pralatrexate
Purinethol
Generic name: Mercaptopurine
Siklos
Generic name: Hydroxyurea
Tabloid
Generic name: Thioguanine
Thioguanine
Generic name: Thioguanine
Xeloda
Generic name: Capecitabine

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