Azole antifungals
What are Azole antifungals?
Azole antifungals are a group of medicines that contain an azole ring and inhibit the growth of a wide range of fungi. They are classified into two groups: those with two nitrogens in the azole ring (the imidazoles; examples include clotrimazole, econazole, ketoconazole, miconazole, and tioconazole) and those with three nitrogens in the azole ring (the triazoles; examples include fluconazole, itraconazole, posaconazole, and voriconazole).
Azole antifungals work by inhibiting the cytochrome P450 dependent enzyme lanosterol 14-alpha-demethylase, which converts lanosterol to ergosterol, the main sterol in the fungal cell membrane. Depletion of ergosterol damages the cell membrane resulting in cell death.
Azole antifungal agents can be used to treat fungal infections of the body and skin, including athlete's foot, onychomycosis (fungal nail infections), ringworm, and vaginal candidiasis.
List drug with Azole antifungals
Drug Name |
---|
Cresemba Generic name: Isavuconazonium Sulfate |
Cresemba (Isavuconazonium Intravenous) Generic name: Isavuconazonium |
Cresemba (Isavuconazonium Oral) Generic name: Isavuconazonium |
Diflucan Generic name: Fluconazole |
Diflucan IV Generic name: Fluconazole |
Fluconazole Generic name: Fluconazole (oral/injection) |
Fluconazole (Intravenous) Generic name: Fluconazole |
Fluconazole (Oral) Generic name: Fluconazole |
Isavuconazonium Generic name: Isavuconazonium |
Isavuconazonium (Intravenous) Generic name: Isavuconazonium |
Isavuconazonium (Oral) Generic name: Isavuconazonium |
Itraconazole Generic name: Itraconazole |
Ketoconazole Generic name: Ketoconazole |
Ketoconazole (Oral) Generic name: Ketoconazole |
Miconazole (Buccal mucosa) Generic name: Miconazole |
Miconazole oral buccal Generic name: Miconazole Oral (buccal) |
Nizoral Generic name: Ketoconazole (oral) |
Nizoral (Ketoconazole Oral) Generic name: Ketoconazole |
Noxafil Generic name: Posaconazole (oral/injection) |
Noxafil (Posaconazole Intravenous) Generic name: Posaconazole |
Noxafil (Posaconazole Oral) Generic name: Posaconazole |
Noxafil PowderMix Generic name: Posaconazole |
Onmel Generic name: Itraconazole |
Oravig Generic name: Miconazole Oral (buccal) |
Oteseconazole Generic name: Oteseconazole |
Posaconazole (Intravenous) Generic name: Posaconazole |
Posaconazole (Oral) Generic name: Posaconazole |
Posaconazole oral/injection Generic name: Posaconazole (oral/injection) |
Sporanox Generic name: Itraconazole |
Sporanox PulsePak Generic name: Itraconazole |
Tolsura Generic name: Itraconazole |
Vfend Generic name: Voriconazole (oral/injection) |
Vfend I.V. Generic name: Voriconazole |
VFEND oral/injection Generic name: Voriconazole (oral/injection) |
Vivjoa Generic name: Oteseconazole |
Voriconazole (Intravenous) Generic name: Voriconazole |
Voriconazole (Oral) Generic name: Voriconazole |
Voriconazole oral/injection Generic name: Voriconazole (oral/injection) |
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