Bisphosphonates

What are Bisphosphonates?

Bisphosphonates are a group of medicines that slow down or prevent bone loss, strengthening bones. Bisphosphonates inhibit osteoclasts which are responsible for breaking down and reabsorbing minerals such as calcium from bone (the process is known as bone resorption). Bisphosphonates allow osteoblasts (bone building cells) to work more effectively, improving bone mass.

Bisphosphonates are used in the treatment of osteoporosis, Paget's disease of bone, and may be used to lower high calcium levels in people with cancer. When used to treat osteoporosis, the optimal duration of treatment is not yet known; however, the majority of benefits appear to happen within the first five years of treatment and long-term use has been associated with atypical femur fractures, osteonecrosis of the jaw and esophageal cancer. Experts recommend the need for bisphosphonate treatment should be reviewed every three to five years.

List drug with Bisphosphonates

Drug Name
Aclasta
Generic name: Zoledronic Acid
Actonel
Generic name: Risedronate
Actonel with Calcium
Generic name: Calcium Carbonate And Risedronate
Alendronate
Generic name: Alendronate
Alendronate and cholecalciferol
Generic name: Alendronate And Cholecalciferol
Aredia
Generic name: Pamidronate
Atelvia
Generic name: Risedronate
Binosto
Generic name: Alendronate
Boniva
Generic name: Ibandronate (oral/injection)
Boniva (Ibandronate Intravenous)
Generic name: Ibandronate
Boniva (Ibandronate Oral)
Generic name: Ibandronate
Didronel
Generic name: Etidronate
Etidronate
Generic name: Etidronate
Fosamax
Generic name: Alendronate
Fosamax Plus D
Generic name: Alendronate And Cholecalciferol
Ibandronate (Intravenous)
Generic name: Ibandronate
Ibandronate (Oral)
Generic name: Ibandronate
Ibandronate oral/injection
Generic name: Ibandronate (oral/injection)
Pamidronate
Generic name: Pamidronate
Reclast
Generic name: Zoledronic Acid
Risedronate
Generic name: Risedronate
Skelid
Generic name: Tiludronate
Tiludronate
Generic name: Tiludronate
Zoledronic acid
Generic name: Zoledronic Acid
Zometa
Generic name: Zoledronic Acid

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