Factor Xa inhibitors

What are Factor Xa inhibitors?

Factor Xa inhibitors are a type of anticoagulant that work by selectively and reversibly blocking the activity of clotting factor Xa, preventing clot formation. They affect both factor Xa within the blood and within a preexisting clot. They do not affect platelet aggregation. They are used for the treatment and prevention of deep vein thrombosis and acute pulmonary embolism, and to reduce the risk of stroke and embolism in people with nonvalvular atrial fibrillation.

Factor Xa is generated by both the extrinsic and intrinsic coagulation pathways and is responsible for activating prothrombin to thrombin. Factor Xa inhibitors have predictable anticoagulant effects and do not require routine monitoring, unlike some other anticoagulants.

Apixaban, edoxaban, fondaparinux, and rivaroxaban are all Factor Xa inhibitors.

List drug with Factor Xa inhibitors

Drug Name
Apixaban
Generic name: Apixaban
Arixtra
Generic name: Fondaparinux
Bevyxxa
Generic name: Betrixaban
Edoxaban
Generic name: Edoxaban
Eliquis
Generic name: Apixaban
Fondaparinux
Generic name: Fondaparinux
Rivaroxaban
Generic name: Rivaroxaban
Savaysa
Generic name: Edoxaban
Xarelto
Generic name: Rivaroxaban
Xarelto Starter Pack
Generic name: Rivaroxaban

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