Peripheral opioid receptor mixed agonists / antagonists

What are Peripheral opioid receptor mixed agonists/antagonists?

Opioid receptors are distributed in the central nervous system and the digestive tract. Peripheral acting agonist and antagonist are not able to penetrate the blood brain barrier so only affect the peripheral opioid receptors. Opioid receptors can be divided into four types including mu, delta, kappa and the nociceptin receptors, and these can be further divided into subtypes. Agonist and antagonist that act on these receptors cause a range of effects depending on the subtype of receptor. By selectively combining peripheral agonists and antagonists that act on particular subtypes of opioid receptor, medications can be produced to have a specific effect with reduced unwanted effects.

List drug with Peripheral opioid receptor mixed agonists / antagonists

Drug Name
Eluxadoline
Generic name: Eluxadoline
Viberzi
Generic name: Eluxadoline

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Popular Keywords