Polyenes

What are Polyenes?

Antifungal agents are also called antimycotic agents.

Polyene antifungals bind to ergosterol, the main sterol in the fungal cell membrane, and cause depolarization of the membrane. This increases the membrane permeability and leads to cell death.

They are not absorbed when given orally, so are used to treat fungal infections of the gastrointestinal tract, such as oral thrush. For treatment of systemic fungal infections they need to be administered intravenously.

List drug with Polyenes

Drug Name
Ambisome
Generic name: Amphotericin B Liposomal
Amphocin
Generic name: Amphotericin B
Amphotec
Generic name: Amphotericin B Cholesteryl Sulfate Complex
Amphotericin B
Generic name: Amphotericin B
Amphotericin b cholesteryl sulfate complex
Generic name: Amphotericin B Cholesteryl Sulfate Complex
Amphotericin B lipid complex
Generic name: Amphotericin B Lipid Complex
Amphotericin B liposomal
Generic name: Amphotericin B Liposomal
Amphotericin b liposome
Generic name: Amphotericin B Liposome
Abelcet
Generic name: Amphotericin B Lipid Complex
Fungizone
Generic name: Amphotericin B

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