Purine nucleosides
What are Purine nucleosides?
Purine nucleosides are antiviral agents that have selective activity against herpes simplex virus types 1 (cold sores) and 2 (genital herpes) and varicella zoster virus (chicken pox).
The purine nucleoside molecule is converted to a monophosphate by viral thymidine kinases. The monophosphate is then converted to diphosphate and then into a triphosphate form by cellular enzymes. The triphosphate form blocks the replication of viral DNA by inhibiting viral DNA polymerase and terminating the growing viral DNA chain.
Purine nucleosides are more potent against the viral enzymes than the host enzymes.
List drug with Purine nucleosides
Drug Name |
---|
Acyclovir Generic name: Acyclovir (oral) |
Acyclovir (Buccal mucosa) Generic name: Acyclovir |
Acyclovir (Oral, Intravenous) Generic name: Acyclovir |
Acyclovir injection Generic name: Acyclovir (injection) |
Cytovene Generic name: Ganciclovir |
Cytovene IV Generic name: Ganciclovir |
Brincidofovir Generic name: Brincidofovir |
Cidofovir Generic name: Cidofovir |
Famciclovir Generic name: Famciclovir |
Famvir Generic name: Famciclovir |
Ganciclovir (Oral, Intravenous) Generic name: Ganciclovir |
Ganciclovir injection Generic name: Ganciclovir (injection) |
Moderiba Generic name: Ribavirin (oral) |
Remdesivir Generic name: Remdesivir |
Sitavig Generic name: Acyclovir (oral) |
Tembexa Generic name: Brincidofovir |
Valacyclovir Generic name: Valacyclovir |
Valcyte Generic name: Valganciclovir |
Valganciclovir Generic name: Valganciclovir |
Valtrex Generic name: Valacyclovir |
Veklury Generic name: Remdesivir |
Vistide Generic name: Cidofovir |
Zovirax Generic name: Acyclovir (oral) |
Zovirax (Acyclovir Oral, Intravenous) Generic name: Acyclovir |
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