Rifamycin derivatives

What are Rifamycin derivatives?

Rifamycin derivatives are antibiotics that work by binding to and inhibiting the mycobacterial DNA dependent RNA polymerase. These antibiotics are bacteriocidal and therefore extremely effective antituberculosis agents, but resistance can develop rapidly if used as a single agent. They easily penetrate into cells, body fluids and cerebrospinal fluid so can be used against organisms in the extracellular component and those that may be present in cells such as macrophages. Rifamycin antibiotics should be used throughout the course of tuberculosis treatment, which can be between nine months to a year.

List drug with Rifamycin derivatives

Drug Name
Mycobutin
Generic name: Rifabutin
Aemcolo
Generic name: Rifamycin
Priftin
Generic name: Rifapentine
Rifabutin
Generic name: Rifabutin
Rifadin
Generic name: Rifampin
Rifadin IV
Generic name: Rifampin
Rifampin
Generic name: Rifampin (oral/injection)
Rifampin (Intravenous)
Generic name: Rifampin
Rifampin (Oral)
Generic name: Rifampin
Rifamycin
Generic name: Rifamycin
Rifapentine
Generic name: Rifapentine
Rimactane
Generic name: Rifampin

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