Serotoninergic neuroenteric modulators

What are Serotoninergic neuroenteric modulators?

Serotoninergic neuroenteric modulators bind to the serotonin receptors in the gastrointestinal tract and either act as an agonist or antagonist.

One of the agents in this class is a selective serotonin receptor antagonist, so it binds to the serotonin receptor and blocks the action of serotonin in the gastrointestinal tract. The agent with serotonin receptor antagonist activity is used to relieve cramping, abdominal discomfort, diarrhea, etc. associated with irritable bowel syndrome.

The other agents in this category are selective serotonin receptor agonists that act in the gastrointestinal tract to regulate bowel function. It is used to treat chronic constipation and constipation related to irritable bowel syndrome.

List drug with Serotoninergic neuroenteric modulators

Drug Name
Alosetron
Generic name: Alosetron (oral)
Lotronex
Generic name: Alosetron (oral)
Motegrity
Generic name: Prucalopride
Prucalopride
Generic name: Prucalopride
Zelnorm
Generic name: Tegaserod

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