SGLT-2 inhibitors

What are SGLT-2 inhibitors?

SGLT-2 inhibitor is an abbreviation for sodium-glucose cotransporter-2 inhibitors. SGLT-2 inhibitors are a class of medicine used to lower high blood glucose levels in people with type 2 diabetes. They may also be called gliflozins.

SGLT-2 inhibitors inhibit SGLT-2 proteins located in the renal tubules of the kidneys which are responsible for reabsorbing glucose back into the blood. As a result, more glucose is excreted in the urine. SGLT-2 inhibitors have been shown to be effective at lowering hemoglobin A1c levels, improving weight loss and lowering blood pressure. They carry a low risk of hypoglycemia (low blood sugar levels).

They are usually well tolerated. SGLT-2 inhibitors may be used in the treatment of type 2 diabetes and act independently of beta-cell function in the pancreas.

List drug with SGLT-2 inhibitors

Drug Name
Bexagliflozin
Generic name: Bexagliflozin
Brenzavvy
Generic name: Bexagliflozin
Canagliflozin
Generic name: Canagliflozin
Dapagliflozin
Generic name: Dapagliflozin
Empagliflozin
Generic name: Empagliflozin
Ertugliflozin
Generic name: Ertugliflozin
Farxiga
Generic name: Dapagliflozin
Invokana
Generic name: Canagliflozin
Jardiance
Generic name: Empagliflozin
Steglatro
Generic name: Ertugliflozin

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