Somatostatin and somatostatin analogs

What are Somatostatin and somatostatin analogs?

Somatostatin is a hormone produced by the hypothalamus and some other tissues such as the pancreas and the gastrointestinal tract. It inhibits the release of growth hormone from the anterior pituitary, and insulin and glucagon from the pancreas.

Somatostatin also decreases the release of most gastrointestinal hormones and reduces gastric acid and pancreatic secretion. It can reduce abdominal blood flow therefore somatostatin analogs can be used to reduce bleeding from esophageal varices.

Somatostatin analogs are used for treatment of tumors secreting vasoactive intestinal peptide, carcinoid tumors, glucagonomas and various pituitary adenomas. It is also used to treat acromegaly (a condition in where there is oversecretion of growth hormone in an adult).

List drug with Somatostatin and somatostatin analogs

Drug Name
Bynfezia Pen
Generic name: Octreotide Acetate
Lanreotide
Generic name: Lanreotide
Octreotide (Injection, Intramuscular, Subcutaneous)
Generic name: Octreotide
Octreotide (Oral)
Generic name: Octreotide
Octreotide oral/injection
Generic name: Octreotide (oral/injection)
Pasireotide
Generic name: Pasireotide
Sandostatin
Generic name: Octreotide Injection
Sandostatin LAR Depot
Generic name: Octreotide
Signifor
Generic name: Pasireotide
Signifor LAR
Generic name: Pasireotide
Somatuline Depot
Generic name: Lanreotide

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