Abrocitinib
Generic name: Abrocitinib
Brand names: Cibinqo
Dosage form: oral tablet (100 mg; 200 mg; 50 mg)
Drug class:
Selective immunosuppressants
Usage of Abrocitinib
Abrocitinib is used in adults to treat moderate-to-severe eczema (atopic dermatitis) that did not respond to other treatments and is not well controlled with other medicines or in adults who cannot tolerate other treatments.
Abrocitinib may also be used for purposes not listed in this medication guide.
Abrocitinib side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Abrocitinib may cause serious side effects. Call your doctor at once if you have:
Common side effects of abrocitinib may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Abrocitinib
You should not use abrocitinib with other medicines that prevent blood clots during the first 3 months of treatment. You can take aspirin (up to a dose of 81 mg each day) during this time if prescribed by your doctor.
Tell your doctor if you:
Tell your doctor if you've had or been exposed to tuberculosis, or if you recently traveled. Some infections are more common in certain parts of the world, and you may have been exposed during travel.
It is not known if abrocitinib will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
If you are pregnant, your name may be listed on a pregnancy registry to track the effects of abrocitinib on the baby.
It may be harder for you to get pregnant while you are using abrocitinib.
Ask a doctor if it is safe to breastfeed while using this medicine.
Relate drugs
- Abrocitinib
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- Amevive
- Anifrolumab
- Anifrolumab-fnia
- Anti-thymocyte globulin rabbit
- Atgam equine
- Aubagio
- Avacopan
- Muromonab-cd3
- Mycophenolate (Intravenous)
- Mycophenolate mofetil
- Mycophenolate mofetil oral/injection
- Mycophenolic acid
- Myfortic
- Bafiertam
- Belatacept
- Belimumab
- Belumosudil
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- Cellcept
- Cellcept (Mycophenolate Intravenous)
- Cellcept (Mycophenolate mofetil Oral)
- Cibinqo
- Dimethyl fumarate
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- Tavneos
- Tecfidera
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- Tyruko
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- Tysabri
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- Vedolizumab
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How to use Abrocitinib
Usual Adult Dose for Atopic Dermatitis:
100 mg orally once a day-Maximum dose: 200 mg/dayDuration of therapy: If no adequate response is achieved with 100 mg/day after 12 weeks, the dose can be increased to 200 mg/day. Discontinue if inadequate response is seen after this dosage increase.Comments:-This drug should not be used in combination with other Janus kinase (JAK) inhibitors, biologic immunomodulators, or immunosuppressants.-This drug can be used with or without topical corticosteroids.Use: Refractory moderate to severe atopic dermatitis in patients, whose condition has not been adequately controlled with other systemic drug products.
Usual Pediatric Dose for Atopic Dermatitis:
100 mg orally once a day-Maximum dose: 200 mg/dayDuration of therapy: If no adequate response is achieved with 100 mg/day after 12 weeks, the dose can be increased to 200 mg/day. Discontinue if inadequate response is seen after this dosage increase.Comments:-This drug should not be used in combination with other Janus kinase (JAK) inhibitors, biologic immunomodulators, or immunosuppressants.-This drug can be used with or without topical corticosteroids.Use: Refractory moderate to severe atopic dermatitis in pediatric patients 12 years of age and older, whose condition has not been adequately controlled with other systemic drug products.
Warnings
Tell your doctor if you've had or been exposed to tuberculosis, or if you recently traveled. Some infections are more common in certain parts of the world, and you may have been exposed during travel.
Abrocitinib may increase your risk of certain cancers, such as lymphoma, lung cancer, and skin cancer. Ask your doctor about your risk.
Call your doctor at once if you have:
What other drugs will affect Abrocitinib
Sometimes it is not safe to use certain medicines at the same time. Some drugs can affect your blood levels of other drugs you use, which may increase side effects or make the medicines less effective.
Tell your doctor about all your other medicines, especially:
This list is not complete. Other drugs may affect abrocitinib, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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