Acetaminophen and ibuprofen

Generic name: Acetaminophen And Ibuprofen
Dosage form: oral tablet (250 mg-125 mg)
Drug class: Analgesic combinations

Usage of Acetaminophen and ibuprofen

Acetaminophen is a pain reliever and a fever reducer. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID).

Acetaminophen and ibuprofen is a combination medicine that is used to treat pain caused by many conditions such as headache, muscle aches, arthritis, backache, toothaches, and menstrual cramps.

Acetaminophen and ibuprofen may also be used for purposes not listed in this medication guide.

Acetaminophen and ibuprofen side effects

Get emergency medical help if you have signs of an allergic reaction (hives; difficulty breathing; swelling of your face, lips, tongue, or throat) or signs of a heart attack or stroke (chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, leg swelling, feeling short of breath).

In rare cases, acetaminophen may cause a severe skin reaction that can be fatal. This could occur even if you have taken acetaminophen in the past and had no reaction. Stop taking acetaminophen and ibuprofen and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling. If you have this type of reaction, you should never again take any medicine that contains acetaminophen.

Stop taking this medicine and call your doctor at once if you have:

  • swelling, rapid weight gain, feeling short of breath;
  • little or no urination;
  • loss of appetite, new or worsening stomach pain;
  • bloody or tarry stools;
  • coughing up blood or vomit that looks like coffee grounds; or
  • dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
  • Less serious side effects may be more likely, and you may have none at all.

    This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Acetaminophen and ibuprofen

    You should not take acetaminophen and ibuprofen if you are allergic to acetaminophen, ibuprofen, aspirin, or another NSAID.

    Ibuprofen can increase your risk of fatal heart attack or stroke, even if you don't have any risk factors. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

    Ibuprofen may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using acetaminophen and ibuprofen, especially in older adults.

    Ask a doctor or pharmacist if this medicine is safe to use if you have ever had:

  • heart disease;
  • high blood pressure;
  • a heart attack, stroke, or blood clot;
  • heartburn, stomach ulcer, or stomach bleeding;
  • cirrhosis or other liver disease;
  • kidney disease;
  • asthma; or
  • if you drink more than 3 alcoholic beverages per day.
  • Ask a doctor before using this medicine if you are pregnant or breastfeeding.

    If you are pregnant, you should not take acetaminophen and ibuprofen unless your doctor tells you to. Taking an NSAID during the last 20 weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your pregnancy.

    Do not give this medicine to a child younger than 12 years old without the advice of a doctor.

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    Warnings

    Use this medicine exactly as directed. An overdose of acetaminophen can damage your liver or cause death.

    Ibuprofen can increase your risk of fatal heart attack or stroke, especially if you use it long term or take high doses, or if you have heart disease. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

    Ibuprofen may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using ibuprofen, especially in older adults.

    Stop taking this medicine and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling.

    What other drugs will affect Acetaminophen and ibuprofen

    Ask your doctor before using acetaminophen and ibuprofen if you take an antidepressant. Taking certain antidepressants with an NSAID may cause you to bruise or bleed easily.

    Other drugs may affect acetaminophen and ibuprofen, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

    Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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