Acetaminophen, aspirin, and caffeine

Generic name: Acetaminophen, Aspirin, And Caffeine
Dosage form: oral tablet (194 mg-227 mg-33 mg; 250 mg-250 mg-65 mg)
Drug class: Analgesic combinations

Usage of Acetaminophen, aspirin, and caffeine

Acetaminophen is a pain reliever and a fever reducer. Aspirin is a salicylate (sa-LIS-il-ATE). Caffeine is a central nervous system stimulant.

Acetaminophen, aspirin, and caffeine is a combination medicine used to treat pain caused by tension headaches, migraine headaches, muscle aches, menstrual cramps, arthritis, toothaches, the common cold, or nasal congestion.

Do not use aspirin for heart or blood vessel conditions unless your doctor tells you to.

Acetaminophen, aspirin, and caffeine may also be used for purposes not listed in this medication guide.

Acetaminophen, aspirin, and caffeine side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

In rare cases, acetaminophen may cause a severe skin reaction that can be fatal. This could occur even if you have taken acetaminophen in the past and had no reaction. Stop taking this medicine and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling. If you have this type of reaction, you should never again take any medicine that contains acetaminophen.

This medicine may cause serious side effects. Stop using this medicine and call your doctor at once if you have:

severe anxiety, agitation, confusion, panic;

easy bruising or bleeding;

a light-headed feeling, like you might pass out;

dehydration symptoms--feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin;

symptoms of stomach bleeding--bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;

high potassium--nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement; or

liver problems--nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Common side effects of acetaminophen, aspirin, and caffeine may include:

upset stomach, heartburn;

depressed mood, feeling anxious or restless; or

sleep problems (insomnia).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Acetaminophen, aspirin, and caffeine

Do not give this medicine to a child or teenager with a fever, flu symptoms, or chicken pox. Aspirin can cause Reye's syndrome, a serious and sometimes fatal condition in children.

You should not use this medicine if you are allergic to acetaminophen (Tylenol), aspirin, caffeine, or any NSAIDs (diclofenac, ibuprofen, indomethacin, meloxicam, naproxen, Advil, Aleve, Motrin, and others).

Aspirin may cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are taking this medicine.

Ask a doctor or pharmacist if this medicine is safe to use if you have ever had:

liver disease, cirrhosis, a history of alcoholism, or if you drink more than 3 alcoholic beverages per day;

asthma or seasonal allergies;

fever with a stiff neck;

stomach ulcer, stomach or intestinal bleeding, ulcerative colitis;

bleeding problems;

kidney disease; or

if you use medicine to treat glaucoma or prevent blood clots.

If you take acetaminophen, aspirin, and caffeine to treat headache pain, seek medical attention if you have:

a headache so bad you have to lie down;

a headache that causes vomiting;

what feels like the worst headache you've ever had;

a headache that seems different from your usual headaches;

a headache every day;

a headache after coughing, bending, exercising, or head injury;

if you have never had migraines diagnosed by a doctor; or

if you are having your first headache after age 50.

Ask a doctor before using this medicine if you are pregnant or breastfeeding.

Taking aspirin during late pregnancy may cause bleeding in the mother or the baby during delivery. Ask a doctor before using this medicine if you are pregnant.

Do not give this medicine to anyone younger than 18 years old without medical advice.

Relate drugs

How to use Acetaminophen, aspirin, and caffeine

Usual Adult Dose for Analgesic/Antipyretic:

2 tablets orally every 6 hoursMaximum dose: 8 tablets in 24 hoursEach tablet contains: acetaminophen 250 mg/aspirin 250 mg/caffeine 65 mgComments: -This combination drug should not be taken with any other drug containing acetaminophen.-Patients should limit their caffeine use while taking this drug. Uses: For the temporary relief of minor aches and pains due to headache, cold, arthritis, muscular aches, toothache, or premenstrual or menstrual cramps.

Usual Pediatric Dose for Analgesic/Antipyretic:

12 years or older: 2 tablets orally every 6 hoursMaximum dose: 8 tablets in 24 hoursEach tablet contains: acetaminophen 250 mg/aspirin 250 mg/caffeine 65 mgComments: -Pediatric patients recovering from the chicken pox or flu-like symptoms should not use this product. -This combination drug should not be taken with any other drug containing acetaminophen.-Patients should limit their caffeine use while taking this drug. Uses: For the temporary relief of minor aches and pains due to headache, cold, arthritis, muscular aches, toothache, or premenstrual or menstrual cramps.

Warnings

Do not give this medicine to a child or teenager with a fever, flu symptoms, or chicken pox. Aspirin can cause Reye's syndrome, a serious and sometimes fatal condition in children.

Do not take more than the recommended dose. An acetaminophen overdose can damage your liver or cause death.

Call your doctor at once if you have: nausea, upper stomach pain, loss of appetite, dark urine, yellowing of your skin or eyes, clay-colored stools, bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds.

In rare cases, acetaminophen may cause a severe skin reaction. Stop taking this medicine and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling.

What other drugs will affect Acetaminophen, aspirin, and caffeine

Other drugs may affect acetaminophen, aspirin, and caffeine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.