Acetaminophen, dextromethorphan, guaifenesin, and pseudoephedrine

Generic name: Acetaminophen, Dextromethorphan, Guaifenesin, And Pseudoephedrine
Dosage form: oral tablet (325 mg-20 mg-200 mg-60 mg)
Drug class: Upper respiratory combinations

Usage of Acetaminophen, dextromethorphan, guaifenesin, and pseudoephedrine

Acetaminophen is a pain reliever and fever reducer.

Dextromethorphan is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

Guaifenesin is an expectorant. It helps loosen congestion in your chest and throat, making it easier to cough out through your mouth.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Acetaminophen, dextromethorphan, guaifenesin, and pseudoephedrine is a combination medicine used to treat headache, fever, body aches, cough, chest congestion, stuffy nose, and sinus congestion caused by allergies, the common cold, or the flu.

acetaminophen, dextromethorphan, guaifenesin, and pseudoephedrine will not treat a cough that is caused by smoking, asthma, or emphysema.

Acetaminophen, dextromethorphan, guaifenesin, and pseudoephedrine may also be used for purposes not listed in this medication guide.

Acetaminophen, dextromethorphan, guaifenesin, and pseudoephedrine side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

In rare cases, acetaminophen may cause a severe skin reaction that can be fatal. This could occur even if you have taken acetaminophen in the past and had no reaction. Stop taking this medicine and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling. If you have this type of reaction, you should never again take any medicine that contains acetaminophen.

This medicine may cause serious side effects. Stop using this medicine and call your doctor at once if you have:

chest pain;

fast, slow, or uneven heart rate;

severe dizziness, feeling like you might pass out;

mood changes, confusion, hallucinations, tremor, seizure (convulsions);

fever;

little or no urinating;

nausea, pain in your upper stomach, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of your skin or eyes); or

dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, chest pain, uneven heartbeats, seizure).

Common side effects of acetaminophen, dextromethorphan, guaifenesin, and pseudoephedrine may include:

dizziness, weakness;

mild headache;

mild nausea, diarrhea, upset stomach;

dry mouth, nose, or throat;

feeling nervous, restless, irritable, or anxious; or

sleep problems (insomnia).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Acetaminophen, dextromethorphan, guaifenesin, and pseudoephedrine

You should not use this medication if you are allergic to acetaminophen, dextromethorphan, guaifenesin, or pseudoephedrine.

Do not use this medicine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

Ask a doctor or pharmacist if it is safe for you to take this medicine if you have other medical conditions, especially:

liver disease, alcoholism, or if you drink more than 3 alcoholic beverages per day;

high blood pressure, heart disease, coronary artery disease, or recent heart attack;

diabetes;

glaucoma;

epilepsy or other seizure disorder;

enlarged prostate or urination problems;

cough with mucus, or cough caused by emphysema or chronic bronchitis;

pheochromocytoma (an adrenal gland tumor); or

overactive thyroid.

It is not known whether acetaminophen, dextromethorphan, guaifenesin, and pseudoephedrine will harm an unborn baby. Do not use this medicine without your doctor's advice if you are pregnant.

This medication may pass into breast milk and may harm a nursing baby. Decongestants may also slow breast milk production. Do not use this medicine without your doctor's advice if you are breast-feeding a baby.

Artificially sweetened liquid medicine may contain phenylalanine. Check the medication label if you have phenylketonuria (PKU).

Relate drugs

How to use Acetaminophen, dextromethorphan, guaifenesin, and pseudoephedrine

Usual Adult Dose for Cough and Nasal Congestion:

Acetaminophen/dextromethorphan/guaifenesin/PSE 500 mg-20 mg-400 mg-60 mg oral tablet:1 tablet orally every 4 to 6 hours not to exceed 4 tablets daily.

Usual Pediatric Dose for Cough and Nasal Congestion:

Acetaminophen/dextromethorphan/guaifenesin/PSE 500 mg-20 mg-400 mg-60 mg oral tablet:6 to 11 years: 1/2 tablet orally every 4 to 6 hours not to exceed 2 tablets daily.12 years or older: 1 tablet orally every 4 to 6 hours not to exceed 4 tablets daily.

Warnings

Do not take more of this medication than is recommended. An overdose of acetaminophen can damage your liver or cause death. Call your doctor at once if you have nausea, pain in your upper stomach, itching, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of your skin or eyes).

In rare cases, acetaminophen may cause a severe skin reaction. Stop taking this medicine and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling.

Acetaminophen is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. Check the label to see if a medicine contains acetaminophen or APAP.

What other drugs will affect Acetaminophen, dextromethorphan, guaifenesin, and pseudoephedrine

Other drugs may interact with acetaminophen, dextromethorphan, guaifenesin, and pseudoephedrine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Disclaimer

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