Acyclovir injection

Generic name: Acyclovir (injection)
Dosage form: intravenous solution (50 mg/mL)
Drug class: Purine nucleosides

Usage of Acyclovir injection

Acyclovir injection is used to treat severe infections caused by herpes viruses, including severe forms of genital herpes, shingles, herpes encephalitis (swelling of the brain), and herpes infections in people with other diseases that weaken the immune system.

Acyclovir will not cure herpes, but it can lessen the symptoms of the infection.

Acyclovir may also be used for purposes not listed in this medication guide.

Acyclovir injection side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Acyclovir may cause serious side effects. Call your doctor at once if you have:

confusion, agitation, hallucinations, feeling less alert than usual;

tremors, seizure;

blood in your urine;

kidney problems--swelling, urinating less, feeling tired or short of breath; or

low blood cell counts--fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath.

Common side effects of acyclovir may include:

swelling or bruising around the IV needle;

nausea, vomiting, loss of appetite;

rash, itching, hives; or

low blood cell counts.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Acyclovir injection

You should not use this medication if you are allergic to acyclovir or valacyclovir (Valtrex).

Tell your doctor if you have ever had:

kidney disease (or if you are on dialysis);

liver disease;

breathing problems; or

an electrolyte imbalance (such as high or low levels of calcium, sodium, or potassium in your blood).

Tell your doctor if you are pregnant. Herpes can be passed to your baby during childbirth if you have a genital lesion when your baby is born. If you have genital herpes, it is very important to prevent herpes lesions during pregnancy. Use your medicine as directed to best control your infection.

Ask a doctor if it is safe to breastfeed while using acyclovir.

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How to use Acyclovir injection

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Treatment with acyclovir should be started as soon as possible after the first appearance of symptoms (such as tingling, burning, blisters).

Acyclovir is given as an infusion into a vein, usually once every 8 hours. A healthcare provider will give your first dose and may teach you how to properly use the medication by yourself.

This medicine must be given slowly, and the infusion can take at least 1 hour to complete.

Acyclovir must be mixed with a liquid (diluent) before using it. When using injections by yourself, be sure you understand how to properly mix and store the medicine. Prepare an injection only when you are ready to give it. Mixed medicine must be used within 24 hours.

Drink plenty of liquids while you are using acyclovir to keep your kidneys working properly.

You may need to use acyclovir injection for up to 21 days. Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses could make your virus resistant to medication.

Lesions caused by herpes viruses should be kept as clean and dry as possible. Wearing loose clothing may help to prevent irritation of the lesions.

Store acyclovir injection at room temperature away from moisture and heat.

Do not reuse a needle or syringe. Place them in a puncture-proof "sharps" container and dispose of it following state or local laws. Keep out of the reach of children and pets.

Warnings

Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

What other drugs will affect Acyclovir injection

Acyclovir can harm your kidneys, especially if you also use certain medicines for infections, cancer, osteoporosis, organ transplant rejection, bowel disorders, high blood pressure, or pain or arthritis (including Advil, Motrin, and Aleve).

Tell your doctor about all your other medicines, especially:

probenecid.

This list is not complete. Other drugs may affect acyclovir, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

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