Adlarity

Generic name: Donepezil
Dosage form: transdermal system
Drug class: Cholinesterase inhibitors

Usage of Adlarity

  • Adlarity is a prescription medicine used to treat mild, moderate, and severe dementia of the Alzheimer’s type.
  • It is not known if this medicine is safe and effective in children.

    • Adlarity side effects

    Adlarity may cause serious side effects, including:

  • Skin reactions. Skin reactions that include redness and itching may happen at the application site. Stop treatment and call your healthcare provider if you get any of these skin reactions and they do not get better within 2 days (48 hours) after the transdermal system is removed:
  • increased redness or swelling
  • peeling or blistering of the skin
  • spreading beyond the application site
  • Slow heartbeat and fainting. Call your healthcare provider right away if you feel faint or lightheaded.
  • More stomach acid. This increases the chance of ulcers and bleeding. The risk is higher for some people, such as those who have had ulcers or take NSAIDs. Call your healthcare provider right away if you have any of these symptoms:
  • heartburn or stomach pain that is new or does not go away.
  • nausea or vomiting, blood in your vomit, or dark vomit that looks like coffee grounds.
  • bowel movements or stools that look like black tar.
  • Problems passing urine. Call your healthcare provider right away if you have problems passing urine.
  • Seizures. Call your healthcare provider right away if you have seizures.
  • Worsening of lung problems in people with asthma or other lung disease. Call your healthcare provider if you have new or worsening lung problems.

    • The most common side effects of donepezil, the medicine in Adlarity, are:

  • nausea
  • diarrhea
  • not sleeping well
  • vomiting
  • muscle cramps
  • feeling tired
  • not wanting to eat

    • These are not all of the possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Adlarity

    You should not use Adlarity if you:

  • are allergic to donepezil or to medicines that contain piperidines. See the end of this page for a complete list of ingredients.
  • have had a skin reaction called allergic contact dermatitis to Adlarity

    • Ask your healthcare provider if you are not sure if you should use the Adlarity transdermal system.

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    How to use Adlarity

    Usual Adult Dose for Alzheimer’s Disease

    - recommended starting dosage is 5 mg/day. After 4 to 6 weeks, the dosage may be increased to the maximum recommended dosage of 10 mg/day. If a patient has been on 5 mg/day oral donepezil for at least 4-6 weeks or on 10 mg/day of oral donepezil, the recommended starting dosage is 10 mg/day. Administer Adlarity as one transdermal system applied to the skin once weekly.

    - Use: treatment of mild, moderate, and severe dementia of the Alzheimer’s type.

    What other drugs will affect Adlarity

    Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Adlarity may affect the way other medicines work and other medicines may affect how Adlarity works. Especially tell your healthcare provider if you take medicines called nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others. Ask your healthcare provider if you are not sure if any of your medicines are NSAIDs. Taking NSAIDs and Adlarity together may make you more likely to get stomach ulcers. Adlarity taken with certain medicines used for anesthesia may cause side effects. Tell your healthcare provider or dentist that you use the Adlarity transdermal system before you have:

  • surgery
  • medical procedures
  • dental surgery or procedures

    • Know the medicines that you take. Keep a list of all of your medicines. Show it to your healthcare provider before you start a new medicine.

    Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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