Advil PM

Generic name: Diphenhydramine And Ibuprofen
Drug class: Analgesic combinations

Usage of Advil PM

Diphenhydramine is an antihistamine. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID).

Advil PM is a combination medicine used to treat occasional insomnia associated with minor aches and pains. Advil PM is not for use in treating sleeplessness without pain, or sleep problems that occur often.

Advil PM is for use in adults and children at least 12 years old.

Advil PM may also be used for purposes not listed in this medication guide.

Advil PM side effects

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Get emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, leg swelling, feeling short of breath.

This medicine may cause serious side effects. Stop using this medicine and call your doctor at once if you have:

  • any skin rash, no matter how mild;
  • a light-headed feeling, like you might pass out;
  • signs of stomach bleeding--bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;
  • kidney problems--little or no urinating, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath; or
  • liver problems--nausea, upper stomach pain, itching, tired feeling, flu-like symptoms, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
  • Common side effects of Advil PM may include:

  • drowsiness;
  • day-time drowsiness, dizziness, "hangover" feeling;
  • upset stomach, heartburn, diarrhea, constipation;
  • dry mouth, nose, or throat;
  • blurred vision;
  • mild itching or rash; or
  • ringing in your ears.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Advil PM

    Ibuprofen can increase your risk of fatal heart attack or stroke, even if you don't have any risk factors. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

    Ibuprofen may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using Advil PM, especially in older adults.

    You should not use this medicine if you are allergic to diphenhydramine or ibuprofen, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID.

    Ask a doctor or pharmacist if this medicine is safe to use if you have ever had:

  • heart disease, high blood pressure;
  • a heart attack, stroke, or blood clot;
  • stomach ulcers or bleeding;
  • a breathing problem, such as asthma, emphysema, or bronchitis;
  • liver or kidney disease;
  • glaucoma;
  • enlarged prostate or problems with urination; or
  • if you take aspirin to prevent heart attack or stroke.
  • Ask a doctor before using this medicine if you are pregnant or plan to become pregnant. Taking ibuprofen during the last 20 weeks of pregnancy may result in serious kidney problems in the unborn baby.

    Ask a doctor before using this medicine if you are breastfeeding.

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    How to use Advil PM

    Use exactly as directed on the label, or as prescribed by your doctor. Use the lowest dose that is effective in treating your condition.

    Taking too much diphenhydramine can lead to serious heart problems, seizures, coma, or death.

    Advil PM is not approved for use by anyone younger than 12 years old. Always ask a doctor before giving an antihistamine to a child. Death can occur from the misuse of antihistamines in very young children.

    Take this medicine with food or milk if it upsets your stomach.

    Do not take this medicine for longer than 10 days without your doctor's advice.

    Call your doctor if your symptoms do not improve, or if they get worse.

    If you need surgery or medical tests, tell the surgeon or doctor ahead of time if you have taken this medicine within the past few days.

    Store at room temperature away from moisture and heat.

    Warnings

    Ibuprofen can increase your risk of fatal heart attack or stroke. Do not use Advil PM just before or after heart bypass surgery (coronary artery bypass graft, or CABG). Ibuprofen may also cause stomach or intestinal bleeding, which can be fatal.

    Use this medicine exactly as directed. Taking too much diphenhydramine can lead to serious heart problems, seizures, coma, or death.

    What other drugs will affect Advil PM

    Ask your doctor before using Advil PM if you take an antidepressant. Taking certain antidepressants with an NSAID may cause you to bruise or bleed easily.

    Ask a doctor or pharmacist before using Advil PM with any other medications, especially:

  • a blood thinner (warfarin, Coumadin, Jantoven);
  • a diuretic or "water pill"; or
  • diphenhydramine (Benadryl) used on the skin.
  • This list is not complete. Other drugs may affect Advil PM, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

    Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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