Afinitor
Generic name: Everolimus
Usage of Afinitor
Afinitor is a cancer medicine that interferes with the growth of cancer cells and slows their spread in the body.
Afinitor is used to treat certain types of kidney cancer, breast cancer, or brain tumor. It is also used to treat certain types of advanced or progressive tumors of the stomach, intestines, or pancreas.
Afinitor is also used to treat certain types of seizures or non-cancerous (benign) tumors of the brain or kidney in people with a genetic condition called tuberous sclerosis complex.
This medication guide provides information about the Afinitor brand of everolimus. Zortress is another brand of everolimus used to prevent organ rejection after a kidney transplant.
Afinitor side effects
Get emergency medical help if you have signs of an allergic reaction to Afinitor: hives; chest pain, difficult breathing; swelling of your face, lips, tongue, or throat. You may be more likely to have some of these symptoms if you also take an "ACE inhibitor" heart or blood pressure medication.
Call your doctor at once if you have:
Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.
Common Afinitor side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Afinitor
You should not use Afinitor if you are allergic to everolimus, sirolimus (Rapamune), or temsirolimus (Torisel).
To make sure Afinitor is safe for you, tell your doctor if you have ever had:
Afinitor can harm an unborn baby or cause birth defects if the mother or the father is using this medicine.
This medicine may affect fertility (ability to have children) in both men and women. However, it is important to use birth control to prevent pregnancy because Afinitor can harm an unborn baby.
You should not breastfeed while using this medicine and for at least 2 weeks after your last dose.
How to use Afinitor
Take Afinitor exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.
Take Afinitor at the same time each day. You may take the medicine with or without food, but take it the same way each time.
Do not take a regular tablet together with a dispersible tablet. Use only one form of this medicine.
Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.
Afinitor can increase your risk of bleeding or infection by changing the way your immune system works. You will need frequent medical tests.
If you've ever had hepatitis B, using Afinitor can cause this virus to become active or get worse. You may need frequent liver function tests while using this medicine and for several months after you stop.
Surgical incisions or other wounds may take longer to heal while you are taking Afinitor. You may need to stop taking this medicine for 1 week before and 2 weeks after a surgery. Follow your doctor's instructions.
Store at room temperature in the original container, away from moisture, heat, and light. Keep unused dispersible tablets in the foil blister pack.
Warnings
Afinitor can cause serious and sometimes fatal side effects. Call your doctor right away if you have: signs of infection--fever, chills, skin rash, joint pain, tiredness; lung problems--cough, chest pain, wheezing, shortness of breath; kidney problems--swelling, little or no urination; or liver problems--loss of appetite, dark urine, yellowing of your skin or eyes, or upper stomach pain.
If you have ever had hepatitis B, Afinitor can cause this condition to come back or get worse.
You may be more likely to have an allergic reaction if you take an "ACE inhibitor" heart or blood pressure medication while you are taking Afinitor. Tell your doctor about all your current medicines and any you start or stop using.
Before taking this medicine, tell your doctor if you have a breathing disorder such as asthma or COPD, liver disease (or a history of hepatitis B), an active infection, diabetes or high blood sugar, or high cholesterol.
Do not use everolimus if you are pregnant. It could harm the unborn baby. Use effective birth control while you are using this medicine and for at least 8 weeks after your treatment ends.
What other drugs will affect Afinitor
Tell your doctor about all your current medicines. Many drugs can affect Afinitor, especially:
This list is not complete and many other drugs may interact with everolimus. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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