Afrezza
Generic name: Insulin Human
Dosage form: inhalation powder
Drug class:
Insulin
Usage of Afrezza
Afrezza side effects
Afrezza may cause serious side effects that can lead to death, including: See Important information
Get emergency medical help if you have:
The most common side effects include:
These are not all the possible side effects of Afrezza. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 (1-800-332-1088).
Before taking Afrezza
Do not use Afrezza if you:
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How to use Afrezza
Usual Adult Dose for Diabetes Type 2:
Insulin-naive: Initial dose: 4 units via oral inhalation at the beginning of each meal Maintenance dose: Adjust dose based on individual's metabolic needs, glucose monitoring results, and glycemic goals Switching from Subcutaneous Mealtime Insulin: Dose conversion as follows: 4 units inhaled insulin replaces up to 4 units of subcutaneous mealtime insulin 8 units inhaled insulin replaces 5 to 8 units of subcutaneous mealtime insulin 12 units inhaled insulin replaces 9 to 12 units of subcutaneous mealtime insulin 16 units inhaled insulin replaces 13 to 16 units of subcutaneous mealtime insulin 20 units inhaled insulin replaces 17 to 20 units of subcutaneous mealtime insulin 24 units inhaled insulin replaces 21 to 24 units of subcutaneous mealtime insulin Switching from Subcutaneous Pre-mixed insulin: -Estimate mealtime injected dose by dividing the total daily injected pre-mixed insulin dose by one-half (half will be the total daily mealtime dose; half will be the daily basal dose) -Divide the total daily mealtime dose equally among the 3 meals of the day; use dose conversion table above -Give the other half the total daily injected dose as injected basal insulin Comments: -Dose adjustments may be needed with changes in physical activity, meal patterns, or during acute illness. -Use a single inhalation per cartridge; doses exceeding 8 units will require multiple cartridges. -Monitor blood glucose, especially in patients requiring high doses; if blood glucose control is not achieved with increasing doses, consider subcutaneous mealtime insulin. Use: Inhaled insulin is a rapid acting insulin for use in adult patients with diabetes mellitus to improve glycemic control.
Usual Adult Dose for Diabetes Type 1:
Insulin-naive: Initial dose: 4 units via oral inhalation at the beginning of each meal Maintenance dose: Adjust dose based on individual's metabolic needs, glucose monitoring results, and glycemic goals Switching from Subcutaneous Mealtime Insulin: Dose conversion as follows: 4 units inhaled insulin replaces up to 4 units of subcutaneous mealtime insulin 8 units inhaled insulin replaces 5 to 8 units of subcutaneous mealtime insulin 12 units inhaled insulin replaces 9 to 12 units of subcutaneous mealtime insulin 16 units inhaled insulin replaces 13 to 16 units of subcutaneous mealtime insulin 20 units inhaled insulin replaces 17 to 20 units of subcutaneous mealtime insulin 24 units inhaled insulin replaces 21 to 24 units of subcutaneous mealtime insulin Switching from Subcutaneous Pre-mixed insulin: -Estimate mealtime injected dose by dividing the total daily injected pre-mixed insulin dose by one-half (half will be the total daily mealtime dose; half will be the daily basal dose) -Divide the total daily mealtime dose equally among the 3 meals of the day; use dose conversion table above -Give the other half the total daily injected dose as injected basal insulin Comments: -Dose adjustments may be needed with changes in physical activity, meal patterns, or during acute illness. -Use a single inhalation per cartridge; doses exceeding 8 units will require multiple cartridges. -Monitor blood glucose, especially in patients requiring high doses; if blood glucose control is not achieved with increasing doses, consider subcutaneous mealtime insulin. Use: Inhaled insulin is a rapid acting insulin for use in adult patients with diabetes mellitus to improve glycemic control.
Warnings
Afrezza can cause serious side effects, including:
What other drugs will affect Afrezza
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins or herbal supplements.
Before you start using Afrezza, talk to your healthcare provider about low blood sugar and how to manage it.
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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