Aggrastat

Generic name: Tirofiban
Drug class: Glycoprotein platelet inhibitors

Usage of Aggrastat

Aggrastat is used to prevent blood clots or heart attack in people with severe chest pain or other conditions, and in those who are undergoing a procedure called angioplasty (to open blocked arteries).

Aggrastat may also be used for purposes not listed in this medication guide.

Aggrastat side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Aggrastat increases your risk of bleeding, which can be severe or life-threatening. Call your doctor or seek emergency medical attention if you have:

easy bruising or bleeding (nosebleeds, bleeding gums);

bleeding around your IV or catheter; or

any bleeding that will not stop.

You may also have bleeding on the inside of your body, such as in your stomach or intestines. Call your doctor at once if you have bloody or tarry stools, or if you cough up blood or vomit that looks like coffee grounds. These could be signs of bleeding in your digestive tract.

Common side effects of Aggrastat may include:

dizziness;

slow heart rate;

leg pain, pelvic pain; or

swelling, increased sweating.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Aggrastat

You should not be treated with Aggrastat if you are allergic to it, or if you have:

any active internal bleeding (stomach, intestines, etc);

a history of bleeding or blood-clotting disorder;

if you have ever had low blood platelets after being treated with Aggrastat; or

if you have had any type of surgery, injury, or medical emergency within the past 30 days.

Tell your doctor if you have ever had:

kidney disease.

Tell your doctor if you are pregnant or plan to become pregnant during treatment, especially if you are also taking aspirin.

You should not breast-feed while using this medicine.

Relate drugs

How to use Aggrastat

Aggrastat is given as an infusion into a vein. A healthcare provider will give you this injection.

While using Aggrastat, you may need frequent blood tests.

Warnings

You should not receive Aggrastat if you have any active internal bleeding (stomach, intestines, etc), a history of bleeding or blood-clotting disorder, if you have ever had low blood platelets after being treated with Aggrastat, or if you have had any type of surgery, injury, or medical emergency within the past 30 days.

What other drugs will affect Aggrastat

Tell your doctor about all your other medicines, especially:

clopidogrel, ticlopidine,

dalteparin, enoxaparin, tinzaparin;

desirudin, dabigatran, fondaparinux.

dipyridamole; or

warfarin, Coumadin, Jantoven.

This list is not complete. Other drugs may affect Aggrastat, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.