Ajovy

Generic name: Fremanezumab-vfrm
Drug class: CGRP inhibitors

Usage of Ajovy

Ajovy is an injectable prescription medicine used to prevent migraine headaches in adults.

Ajovy works by blocking the activity of calcitonin gene-related peptide (CGRP).

Ajovy may also be used for purposes not listed in this medication guide.

Ajovy side effects

Get emergency medical help if you have signs of an allergic reaction to Ajovy: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

An allergic reaction to fremanezumab-vfrm can occur up to 1 month after an injection.

Common Ajovy side effects may include:

  • pain, redness, or a hard lump where the medicine was injected.

    • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Ajovy

    You should not use Ajovy if you are allergic to fremanezumab-vfrm.

    Ajovy is not approved for use by anyone younger than 18 years old.

    Tell your doctor if you are pregnant. It is not known whether this medicine will harm an unborn baby. However, having migraines during pregnancy may cause complications such as preeclampsia (which can lead to medical problems in both mother and baby). The benefit of preventing migraines may outweigh any risks to the baby.

    It may not be safe to breast-feed while using fremanezumab-vfrm. Ask your doctor about any risk.

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    How to use Ajovy

    Usual Adult Dose for Migraine Prophylaxis:

    225 mg subcutaneously once a month -Alternatively, 675 mg subcutaneously may be administered once every 3 months Comments: -To administer 675 mg subcutaneously, 3 consecutive subcutaneous injections of 225 mg are given. -If switching dosage options, administer the first dose of the new regimen on the next scheduled date of administration. Use: For the preventive treatment of migraine.

    Warnings

    Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

    What other drugs will affect Ajovy

    Other drugs may interact with fremanezumab-vfrm, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

    Popular FAQ

    You can leave Ajovy out of the fridge for up to 7 days at room temperature (up to 86°F or 30°C). Do not use your Ajovy if it has been at room temperature for 7 days or longer. Once it is stored at room temperature do not put it back in the refrigerator. Do not put Ajovy in the sunlight, or use hot water or a microwave to warm the injections.

    There are no known drug interactions between Ajovy (fremanezumab) and ibuprofen (Advil, Motrin), but you should talk to your doctor before you combine these medications. Serious side effects can occur with ibuprofen, such as stomach or intestinal bleeding, rash, swelling, problems with your kidneys, or an increased risk of heart attack and stroke. Ajovy is used to help prevent migraine episodes in adults. Ibuprofen is an over-the-counter analgesic used as an acute treatment to help stop migraine pain already in progress. If Ajovy is not adequately helping your migraine, your doctor may want to switch you to a different migraine prevention medicine or drug class.

    Weight gain has not been reported as a side effect in studies with the migraine prevention medicine Ajovy, but some anecdotal reports do note this effect. Other factors, such as lack of physical activity due to migraine pain may play a role in weight gain in patients with migraine headaches. Continue reading

    Most patients usually respond within a month of starting Ajovy treatment, and some respond within one week, if the medicine works for them. In general, Ajovy can help to reduce the number of migraine headache days you have by about 1.5 to 2 days per month. Continue reading

    Ajovy works to help prevent migraine pain by binding to the calcitonin gene-related peptide (CGRP) ligand to prevent its binding to the receptor. Ajovy is in the class of medicines known as calcitonin gene-related peptide (CGRP) inhibitors. It is not used to treat an ongoing migraine headache. Continue reading

    Ajovy and Aimovig are both calcitonin gene-related peptide (CGRP) inhibitors used for migraine prevention in adults. The dosing, side effects, effectiveness and costs of these medicines can vary. As demonstrated in studies, these agents can reduce the number of migraine headache days you experience by about 1.5 to 3 days per month when compared to a placebo (inactive) treatment, but your response may vary. Continue reading

    The Ajovy autoinjector is given as a subcutaneous injection (under the skin). You can learn to give yourself this injection to help prevent migraine headaches. Your healthcare provider can show you how to prepare and inject your dose of Ajovy before the first dose. Use Ajovy exactly as your doctor or other healthcare provider tells you how to use it. Continue reading

    There are no known drug interactions between Ajovy (fremanezumab) and ibuprofen (Advil, Motrin), but you should talk to your doctor before you combine these medications. Serious side effects can occur with ibuprofen, such as stomach or intestinal bleeding, rash, swelling, problems with your kidneys, or an increased risk of heart attack and stroke. Ajovy is used to help prevent migraine episodes in adults. Ibuprofen is an over-the-counter analgesic used as an acute treatment to help stop migraine pain already in progress. If Ajovy is not adequately helping your migraine, your doctor may want to switch you to a different migraine prevention medicine or drug class.

    You can leave Ajovy out of the fridge for up to 7 days at room temperature (up to 86°F or 30°C). Do not use your Ajovy if it has been at room temperature for 7 days or longer. Once it is stored at room temperature do not put it back in the refrigerator. Do not put Ajovy in the sunlight, or use hot water or a microwave to warm the injections.

    Weight gain has not been reported as a side effect in studies with the migraine prevention medicine Ajovy, but some anecdotal reports do note this effect. Other factors, such as lack of physical activity due to migraine pain may play a role in weight gain in patients with migraine headaches. Continue reading

    Most patients usually respond within a month of starting Ajovy treatment, and some respond within one week, if the medicine works for them. In general, Ajovy can help to reduce the number of migraine headache days you have by about 1.5 to 2 days per month. Continue reading

    Ajovy works to help prevent migraine pain by binding to the calcitonin gene-related peptide (CGRP) ligand to prevent its binding to the receptor. Ajovy is in the class of medicines known as calcitonin gene-related peptide (CGRP) inhibitors. It is not used to treat an ongoing migraine headache. Continue reading

    Ajovy and Aimovig are both calcitonin gene-related peptide (CGRP) inhibitors used for migraine prevention in adults. The dosing, side effects, effectiveness and costs of these medicines can vary. As demonstrated in studies, these agents can reduce the number of migraine headache days you experience by about 1.5 to 3 days per month when compared to a placebo (inactive) treatment, but your response may vary. Continue reading

    The Ajovy autoinjector is given as a subcutaneous injection (under the skin). You can learn to give yourself this injection to help prevent migraine headaches. Your healthcare provider can show you how to prepare and inject your dose of Ajovy before the first dose. Use Ajovy exactly as your doctor or other healthcare provider tells you how to use it. Continue reading

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