Aleve PM

Generic name: Diphenhydramine And Naproxen
Drug class: Analgesic combinations

Usage of Aleve PM

Aleve PM contains a combination of diphenhydramine and naproxen. Diphenhydramine is an antihistamine. Naproxen is a nonsteroidal anti-inflammatory drug (NSAID).

Aleve PM is used to treat occasional insomnia associated with minor aches and pains. This medicine is not for use in treating sleeplessness without pain, or sleep problems that occur often.

Aleve PM is for use in adults and children at least 12 years old.

Aleve PM side effects

Get emergency medical help if you have signs of an allergic reaction to Aleve PM (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Get emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, leg swelling, feeling short of breath.

Stop using this medicine and call your doctor at once if you have:

any skin rash, no matter how mild;

a light-headed feeling, like you might pass out;

new symptoms, such redness or swelling with pain; or

signs of stomach bleeding - bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds.

Common Aleve PM side effects may include:

drowsiness;

day-time drowsiness, dizziness, "hangover" feeling;

upset stomach, heartburn;

constipation;

blurred vision; or

dry mouth, nose, or throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Aleve PM

Naproxen can increase your risk of fatal heart attack or stroke, even if you don't have any risk factors. Do not use Aleve PM just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

Naproxen may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using Aleve PM, especially in older adults.

You should not use Aleve PM if you are allergic to diphenhydramine or naproxen, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID.

Ask a doctor or pharmacist if Aleve PM is safe to use if you have ever had:

heart disease, high blood pressure;

a heart attack, stroke, or blood clot;

stomach ulcers or bleeding;

a breathing problem, such as asthma, emphysema, or bronchitis;

liver or kidney disease;

glaucoma;

enlarged prostate or problems with urination; or

if you take aspirin to prevent heart attack or stroke.

Ask a doctor before using this medicine if you are pregnant or plan to become pregnant.

If you are pregnant, you should not take Aleve PM unless your doctor tells you to. Taking an NSAID during the last 20 weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your pregnancy.

Ask a doctor before using this medicine if you are breastfeeding.

Relate drugs

How to use Aleve PM

Usual Adult Dose for Insomnia:

Initial dose: 2 caplets at bedtime Maximum dose: 2 caplets in 24 hours Use: To relief occasional sleeplessness associated with minor aches

Usual Adult Dose for Pain:

Initial dose: 2 caplets at bedtime Maximum dose: 2 caplets in 24 hours Use: To relief occasional sleeplessness associated with minor aches

Usual Pediatric Dose for Insomnia:

For children over 12 years old. Initial dose: 2 caplets at bedtime Maximum dose: 2 caplets in 24 hours

Usual Pediatric Dose for Pain:

For children over 12 years old. Initial dose: 2 caplets at bedtime Maximum dose: 2 caplets in 24 hours

Warnings

Use Aleve PM exactly as directed. Taking too much diphenhydramine can lead to serious heart problems, seizures, coma, or death.

Naproxen can increase your risk of fatal heart attack or stroke. Do not use Aleve PM just before or after heart bypass surgery (coronary artery bypass graft, or CABG). Naproxen may also cause stomach or intestinal bleeding, which can be fatal.

What other drugs will affect Aleve PM

Ask your doctor before using Aleve PM if you take an antidepressant. Taking certain antidepressants with an NSAID may cause you to bruise or bleed easily.

Ask a doctor or pharmacist before using Aleve PM with any other medications, especially:

a blood thinner (warfarin, Coumadin, Jantoven);

a diuretic or "water pill"; or

diphenhydramine (Benadryl) used on the skin.

This list is not complete. Other drugs may interact with diphenhydramine and naproxen, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Disclaimer

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