Alogliptin

Generic name: Alogliptin
Brand names: Nesina
Dosage form: oral tablet (12.5 mg; 25 mg; 6.25 mg)
Drug class: Dipeptidyl peptidase 4 inhibitors

Usage of Alogliptin

Alogliptin is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. alogliptin is not for treating type 1 diabetes.

Alogliptin is sometimes used in combination with other diabetes medications.

Alogliptin may also be used for purposes not listed in this medication guide.

Alogliptin side effects

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Stop taking alogliptin and call your doctor right away if you have symptoms of pancreatitis: severe pain in your upper stomach spreading to your back, nausea and vomiting, loss of appetite, or fast heartbeats.

Alogliptin may cause serious side effects. Call your doctor at once if you have:

severe or ongoing pain in your joints;

heart problems--shortness of breath (even while lying down), rapid weight gain, swelling (especially in your feet, legs, or midsection);

liver problems--nausea, upper stomach pain, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or

a severe autoimmune reaction--itching, blisters, breakdown of the outer layer of skin.

Common side effects of alogliptin may include:

headache; or

cold symptoms such as stuffy nose, sinus pain, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Alogliptin

You should not use this medicine if you are allergic to alogliptin, or if you have diabetic ketoacidosis (call your doctor for treatment).

Tell your doctor if you have ever had:

liver disease;

heart disease;

kidney disease (or if you are on dialysis);

pancreatitis;

gallstones; or

alcoholism.

Follow your doctor's instructions about using this medicine if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

Alogliptin is not approved for use by anyone younger than 18 years old.

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How to use Alogliptin

Usual Adult Dose for Diabetes Type 2:

Usual dose: 25 mg orally once a day Comments: When used in combination with insulin or insulin secretagogues such as sulfonylureas, a lower dose of insulin or the insulin secretagogue may be required to minimize the risk of hypoglycemia. Use: As an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus; may be used as monotherapy or in combination therapy .

Warnings

Alogliptin can cause serious side effects on your heart or pancreas, especially if you have ever had similar problems, or if you have kidney or liver disease.

Call your doctor right away if you have: signs of pancreatitis--severe pain in your upper stomach spreading to your back; or signs of heart failure--shortness of breath while lying down, weight gain, swelling in your legs or feet.

alogliptin is not for treating type 1 diabetes.

What other drugs will affect Alogliptin

Other drugs may increase or decrease the effects of alogliptin on lowering your blood sugar. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Disclaimer

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