Ambrisentan
Generic name: Ambrisentan
Brand names: Letairis
Dosage form: oral tablet (10 mg; 5 mg)
Drug class:
Agents for pulmonary hypertension
Usage of Ambrisentan
Ambrisentan lowers blood pressure in your lungs, helping your heart pump blood more efficiently.
Ambrisentan is used to treat pulmonary arterial hypertension (PAH) in adults. It improves your ability to exercise and prevents your condition from getting worse. Ambrisentan is sometimes used with a medicine called tadalafil (Adcirca).
For women, ambrisentan is available only from a certified pharmacy under a special program. You must be registered in the program and sign agreements to use birth control and undergo pregnancy and blood testing.
Ambrisentan may also be used for purposes not listed in this medication guide.
Ambrisentan side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Ambrisentan may cause serious side effects. Call your doctor at once if you have:
Common side effects of ambrisentan may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Ambrisentan
You should not use ambrisentan if you are allergic to it, or if you have idiopathic pulmonary fibrosis (IPF).
Do not use ambrisentan if you are pregnant or think you might be pregnant. This medicine can cause serious birth defects. Tell your doctor right away if you miss a menstrual period or think you may have become pregnant.
You will need to have a negative pregnancy test before starting this treatment. You will be re-tested every month during your treatment, and 1 month after your last dose.
Even if you are not planning a pregnancy, you are considered able to become pregnant if:
While taking ambrisentan and for at least 30 days after your last dose, you must use a highly effective form of birth control or two methods together.
Recommended forms of birth control forms include:
Ambrisentan comes with patient instructions about acceptable forms of birth control to use while taking this medicine. Follow these directions carefully. Ask your doctor about emergency contraception if you have unprotected sex or if you believe your contraception has failed.
Tell your doctor if you have ever had:
You should not breastfeed while you are using ambrisentan.
Ambrisentan may lower a man's sperm count and could affect fertility (your ability to have children).
Relate drugs
- Adcirca
- Alyq
- Ambrisentan
- Bosentan
- Epoprostenol
- Flolan
- Iloprost
- Iloprost inhalation
- Letairis
- Liqrev
- Macitentan
- Opsumit
- Orenitram
- Orenitram Titration Kit Month 1
- Orenitram Titration Kit Month 2
- Orenitram Titration Kit Month 3
- Remodulin
- Remodulin injection
- Revatio
- Revatio (Sildenafil Intravenous)
- Revatio (Sildenafil Oral)
- Selexipag (Intravenous)
- Selexipag (Oral)
- Selexipag oral/injection
- Tracleer
- Treprostinil
- Treprostinil (Oral)
- Treprostinil inhalation
- Treprostinil injection
- Tyvaso
- Tyvaso DPI
- Tyvaso DPI Maintenance Kit inhalation
- Tyvaso DPI Titration Kit inhalation
- Tyvaso Starter Kit (Institutional) inhalation
- Uptravi
- Uptravi (Selexipag Intravenous)
- Uptravi (Selexipag Oral)
- Veletri
- Ventavis
How to use Ambrisentan
Usual Adult Dose for Pulmonary Hypertension:
Initial dose: 5 mg orally once a day. Comments:-Consider increasing the dose to 10 mg orally once a day if 5 mg is tolerated.-When used with tadalafil, the dose of either drug can be increased as needed and tolerated at 4-week intervals. Uses:-For the treatment of pulmonary arterial hypertension (WHO Group 1) to improve exercise ability and delay clinical worsening.-For the treatment of pulmonary arterial hypertension (WHO Group 1) in combination with tadalafil to reduce the risks of disease progression and hospitalization for worsening pulmonary arterial hypertension, and to improve exercise ability.
Warnings
Do not use if you are pregnant or think you might be pregnant. You will need to take a pregnancy test before, during, and after treatment with ambrisentan. Use highly effective birth control while using ambrisentan and for at least 30 days after your last dose.
You should not use ambrisentan if you have idiopathic pulmonary fibrosis.
What other drugs will affect Ambrisentan
Tell your doctor about all your other medicines, especially:
This list is not complete. Other drugs may affect ambrisentan, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Popular Keywords
- metformin obat apa
- alahan panjang
- glimepiride obat apa
- takikardia adalah
- erau ernie
- pradiabetes
- besar88
- atrofi adalah
- kutu anjing
- trakeostomi
- mayzent pi
- enbrel auto injector not working
- enbrel interactions
- lenvima life expectancy
- leqvio pi
- what is lenvima
- lenvima pi
- empagliflozin-linagliptin
- encourage foundation for enbrel
- qulipta drug interactions