Amikacin liposome
Generic name: Amikacin Liposome
Brand names: Arikayce
Dosage form: inhalation suspension (590 mg/8.4 mL)
Drug class:
Aminoglycosides
Usage of Amikacin liposome
Amikacin liposome is an antibiotic that is used to treat Mycobacterium avium complex (MAC) lung disease in adults who have few or no other treatment options. Amikacin liposome is given in combination with other antibiotics.
Amikacin liposome is given only to certain adults, when other antibiotics have failed to clear their MAC infections after 6 months of treatment.
Amikacin liposome was approved by the US Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, some people responded to amikacin liposome, but further studies are needed.
Amikacin liposome may also be used for purposes not listed in this medication guide.
Amikacin liposome side effects
Amikacin liposome can cause a serious allergic reaction that may lead to death. Stop using this medicine and get emergency medical help if you have signs of an allergic reaction:
Amikacin liposome may cause serious side effects. Call your doctor at once if you have:
Common side effects of amikacin liposome may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Amikacin liposome
You should not use this medicine if you are allergic to amikacin liposome or similar antibiotics (gentamicin, kanamycin, neomycin, paromomycin, streptomycin, or tobramycin).
Tell your doctor if you have ever had:
Taking amikacin in oral form during pregnancy may cause the baby to be born deaf. It is not known whether amikacin as an inhaled medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.
Relate drugs
- Amikacin
- Amikacin liposome
- Amikin
- Amikin Pediatric
- Arikayce
- Garamycin
- Garamycin (Gentamicin Injection)
- Gentamicin
- Gentamicin (Injection)
- Kanamycin
- Kantrex
- Neo-Fradin
- Neomycin
- Neomycin (Oral)
- Plazomicin
- Zemdri
How to use Amikacin liposome
Usual Adult Dose for Mycobacterium avium-intracellulare -- Treatment:
590 mg inhaled via Lamira (TM) nebulizer once a dayComments:-Patients using bronchodilators should use the bronchodilator prior to using this drug.-Pretreatment with short-acting beta-2 agonists should be considered in patients with specific patient populations (e.g., asthma, bronchospasm, chronic obstructive pulmonary disease, hyperactive airway disease).Use: Patients who have limited or no alternative treatment options for the treatment of Mycobacterium avium complex (MAC) lung disease as part of a combination antibacterial drug regimen in patients who do not achieve negative sputum cultures after a minimum of 6 consecutive months of a multidrug background regimen therapy
Warnings
Amikacin liposome can cause a life-threatening allergic reaction. Stop using amikacin liposome and get emergency medical help if you have symptoms such as: cough, trouble breathing, itching or hives, vomiting, diarrhea, fast heartbeats, feeling light-headed, or swelling in your face or throat.
Amikacin liposome can cause breathing problems. Call your doctor if you have chest tightness, cough, wheezing, trouble breathing, fever, or if you cough up blood.
Certain breathing disorders may become worse while you are using amikacin liposome.
What other drugs will affect Amikacin liposome
Amikacin can harm your kidneys, especially if you also use certain medicines for infections, cancer, osteoporosis, organ transplant rejection, bowel disorders, high blood pressure, or pain or arthritis (including Advil, Motrin, and Aleve).
This list is not complete. Other drugs may affect amikacin liposome, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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