Aminolevulinic acid

Generic name: Aminolevulinic Acid (oral)
Brand names: Gleolan
Dosage form: oral powder for reconstitution (30 mg/mL)
Drug class: Malignancy photosensitizers

Usage of Aminolevulinic acid

Aminolevulinic acid is given before surgery to remove a glioma (a type of brain or spinal cord tumor).

Taking aminolevulinic acid causes a certain substance to build up within your tumor tissue. This allows the tissue to be seen more clearly through a special light scope that is used during surgery to remove the tumor.

Aminolevulinic acid may also be used for purposes not listed in this medication guide.

Aminolevulinic acid side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Your caregivers will watch you closely to make sure you do not have an allergic reaction, and to treat a reaction if it does occur.

Many side effects can occur up to 6 weeks after you took aminolevulinic acid. Call your doctor at once if you have:

a light-headed feeling, like you might pass out;

skin redness or swelling, raised red areas;

skin rash, itching, or blistering;

a seizure;

chills; or

trouble speaking or understanding what is said to you.

Common side effects of aminolevulinic acid may include:

nausea, vomiting, diarrhea; or

abnormal liver function tests (for up to 6 weeks after taking aminolevulinic acid).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Aminolevulinic acid

You should not use aminolevulinic acid if you are allergic to aminolevulinic acid or porphyrins, or if you have:

porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system).

Tell your doctor if you have ever had liver or kidney disease.

Tell your doctor if you are pregnant.

Do not breastfeed within 24 hours after using aminolevulinic acid. If you use a breast pump during this time, throw out the milk and do not feed it to your baby.

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Warnings

For 48 hours after taking aminolevulinic acid, you will need to protect your skin from light, both sunlight and bright indoor light.

What other drugs will affect Aminolevulinic acid

Tell your doctor about all your other medicines. Certain medicines also can make you more sensitive to bright light and should be avoided within 24 hours before or after you take aminolevulinic acid. This includes:

St. John's wort;

an antifungal medicine;

an antibiotic or sulfa medicine;

a diuretic or "water pill";

topical medicine containing aminolevulinic acid;

antipsychotic medicine; or

an oral diabetes medicine.

This list is not complete. Other drugs may affect aminolevulinic acid, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Disclaimer

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