Amondys 45

Generic name: Casimersen
Drug class: Miscellaneous uncategorized agents

Usage of Amondys 45

Amondys 45 is used to treat Duchenne muscular dystrophy in adults and children who have a certain gene mutation. Your doctor will test you for this gene mutation.

Amondys 45 was approved by the US Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, some people responded to Amondys 45, but further studies are needed.

Amondys 45 may also be used for purposes not listed in this medication guide.

Amondys 45 side effects

Get emergency medical help if you have signs of an allergic reaction: hives, itching, rash, blistering or peeling; fever; difficult breathing; swelling of your face, lips, tongue, or throat.

Amondys 45 may cause serious side effects. Call your doctor at once if you have:

pink, brown, or red urine;

foamy urine; or

swelling in your face, hands, feet, or stomach.

Common side effects of Amondys 45 may include:

headache;

fever;

joint pain;

cough; or

cold symptoms such as stuffy nose, sneezing, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Amondys 45

Tell your doctor if you have ever had kidney problems.

Tell your doctor if you are pregnant or breastfeeding.

Relate drugs

How to use Amondys 45

Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using Amondys 45.

Amondys 45 is given as an infusion into a vein, usually once per week. A healthcare provider will give you this injection.

Amondys 45 must be given slowly, and the infusion can take 35 to 60 minutes to complete.

Your kidney function may need to be checked while you are using this medicine.

Amondys 45 doses are based on weight. Your dose needs may change if you gain or lose weight.

Warnings

Before using Amondys 45 tell your doctor about all your medical conditions or allergies, all medicines you use, and if you are pregnant or breastfeeding.

What other drugs will affect Amondys 45

Other drugs may affect Amondys 45, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Popular FAQ

The new drugs approved by the FDA for the treatment of Duchenne Muscular Dystrophy (DMD) are Amondys 45 (casimersen), Viltepso (viltolarsen), Vyondys 53 (golodirsen), Exondys 51 (eteplirsen), Elevidys (delandistrogene moxeparvovec), and Emflaza (deflazacort). They include antisense oligonucleotides, a glucocorticoid and a gene therapy. Duchenne muscular dystrophy (DMD) is a genetic disease that causes progressive weakness, loss of motor function and damage to skeletal and heart muscles. DMD, which has no cure, primarily affects males starting in early childhood, usually between 2 and 3 years of age. Continue reading

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.