Amoxicillin, omeprazole, and rifabutin

Generic name: Amoxicillin, Omeprazole, And Rifabutin
Brand names: Talicia
Dosage form: oral delayed release capsule (250 mg-10 mg-12.5 mg)
Drug class: H. pylori eradication agents

Usage of Amoxicillin, omeprazole, and rifabutin

Amoxicillin is a penicillin antibiotic. Omeprazole is a proton pump inhibitor that decreases stomach acid. Rifabutin is an antibiotic that fights bacteria.

Amoxicillin, omeprazole, and rifabutin is a combination medicine that is used to treat Helicobacter pylori (H. pylori) infection in adults.

Amoxicillin, omeprazole, and rifabutin may also be used for purposes not listed in this medication guide.

Amoxicillin, omeprazole, and rifabutin side effects

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Amoxicillin, omeprazole, and rifabutin may cause serious side effects. Call your doctor at once if you have:

severe stomach pain, diarrhea that is watery or bloody (even if it occurs months after your last dose);

a light-headed feeling, like you might pass out;

easy bruising, unusual bleeding, purple or red spots under your skin;

eye pain or redness, vision problems, seeing spots, your eyes may be more sensitive to light;

flu-like symptoms--fever, chills, sweating, tiredness, body aches, vomiting, chest pain, cough, feeling short of breath;

kidney problems--urinating more or less than usual, fever, nausea, vomiting, blood in your urine, confusion, swelling, rapid weight gain; or

lupus-like symptoms--muscle or joint pain, flu symptoms, chest pain, and a rash or patchy skin color that worsens in sunlight.

Common side effects of amoxicillin, omeprazole, and rifabutin may include:

red, orange, or brown discoloration of your skin, tears, sweat, saliva, urine, or stools;

indigestion, stomach pain, nausea, vomiting, diarrhea;

headache;

discolored urine;

sore throat;

rash; or

vaginal itching or discharge.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Amoxicillin, omeprazole, and rifabutin

You should not use amoxicillin, omeprazole, and rifabutin if you are allergic to amoxicillin (Amoxil, Augmentin), omeprazole (Prilosec), or rifabutin (Mycobutin).

Many drugs can interact and cause dangerous effects. Some drugs should not be used together with amoxicillin, omeprazole, and rifabutin. Your doctor may change your treatment plan if you also use:

delavirdine;

rilpivirine (Juluca); or

voriconazole.

Tell your doctor if you have ever had:

an allergic reaction to an antibiotic medicine;

lupus;

liver disease;

kidney disease; or

mononucleosis.

Amoxicillin, omeprazole, and rifabutin may harm an unborn baby. Use effective birth control to prevent pregnancy, and tell your doctor if you become pregnant.

This medicine can make hormonal birth control less effective, including birth control pills, injections, implants, skin patches, and vaginal rings. To prevent pregnancy while using amoxicillin, omeprazole, and rifabutin, use a barrier form of birth control: condom, diaphragm, cervical cap, or contraceptive sponge.

This medicine may affect fertility (ability to have children) in men.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

Amoxicillin, omeprazole, and rifabutin is not approved for use by anyone younger than 18 years old.

Relate drugs

How to use Amoxicillin, omeprazole, and rifabutin

Usual Adult Dose for Helicobacter pylori Infection:

Amoxicillin 250 mg-omeprazole 10 mg-rifabutin 12.5 mg oral capsules: 4 capsules orally every 8 hours-Duration of therapy: 14 daysComments:-Capsules should be swallowed with at least 8 ounces of water.-This drug should be used to treat infections proven/strongly suspected to be caused by susceptible bacteria.-Antibiotic selection should be determined by local bacterial resistance, duration of treatment, and appropriate use.Use: Treatment of Helicobacter pylori infection

Warnings

Tell your doctor if you have ever had an allergic reaction to an antibiotic medicine.

Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.

What other drugs will affect Amoxicillin, omeprazole, and rifabutin

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect the blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Tell your doctor about all your current medicines. Many drugs can affect amoxicillin, omeprazole, and rifabutin, especially:

allopurinol;

clopidogrel;

digoxin;

methotrexate;

St. John's wort;

tacrolimus;

an antibiotic--clarithromycin, rifampin, telithromycin;

antifungal medicine--fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole;

antiviral medicine to treat HIV/AIDS--fosamprenavir, indinavir, lopinavir, nelfinavir, ritonavir, saquinavir, tipranavir; or

a blood thinner--warfarin, Coumadin, Jantoven.

This list is not complete and many other drugs may affect amoxicillin, omeprazole, and rifabutin. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.