Amvuttra

Generic name: Vutrisiran
Dosage form: injection, for subcutaneous use
Drug class: Miscellaneous metabolic agents

Usage of Amvuttra

Amvuttra is used to treat polyneuropathy (damage of multiple nerves throughout the body) in adults with hereditary transthyretin-mediated amyloidosis (hATTR).

Amvuttra may also be used for purposes not listed in this medication guide.

Amvuttra side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Common side effects of Amvuttra may include:

joint stiffness (arthralgia)

shortness of breath (dyspnea)

decreased vitamin A levels.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Amvuttra

Before using Amvuttra tell your doctor about all your medical conditions or allergies.

It is not known whether Amvuttra will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

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How to use Amvuttra

Usual Adult Dose for Amyloidogenic Transthyretin Amyloidosis:

25 mg administered by subcutaneous injection once every 3 months.

Use: treatment of the polyneuropathy of hereditary transthyretin-mediated amyloidosis in adults

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

What other drugs will affect Amvuttra

Other drugs may affect vutrisiran, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Disclaimer

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