Andrachne

Generic name: Andrachne Aspera Spreng., Andrachne Cordifolia (Wall. Ex Decne.) Müll. Arg., Andrachne Phyllanthoides (Nutt.) Muell. Arg.
Brand names: Andrachne, Maidenbush

Usage of Andrachne

Analgesic

Animal data

In 3 separate tests, administration of A. aspera root extract provided antinociceptive effects in mice that were statistically significantly better than the vehicle with at least comparable effects to the positive control, meperidine. A dose-dependent effect was observed in the tail-flick test with both the 600 mg/kg and 900 mg/kg doses, producing significantly better effects compared to meperidine.Debebe 2007

Antimicrobial activity

In vitro data

A. cordifolia was shown to possess phytotoxic properties in an in vitro study conducted in Pakistan.Gilani 2010 Activity against human pathogens has been evaluated in vitro, with low activity demonstrated by methanolic fractions. A chloroform fraction was active against Salmonella typhi and Pseudomonas aeruginosa. Some activity against fungi was demonstrated.Ahmad 2007

Clinical data

A. aspera roots are used for treating eye inflammation in Yemen, where pieces of crushed root are placed on the eyelids; however, clinical studies are lacking.Ghazanfur 1994

Enzyme inhibitory effects

In vitro data

An in vitro study reported enzyme inhibitory activity of the methanolic extract of A. cardifolia Muell. Activity was shown against lipoxygenase and butyrylcholinesterase, with limited activity against acetylcholinesterase and no activity against urease.Ahmed 2007

Andrachne side effects

Information regarding adverse reactions with use of andrachne is limited.

Before taking Andrachne

Avoid use. Information regarding safety and efficacy in pregnancy and lactation is lacking.

How to use Andrachne

Clinical evidence is lacking to provide dosing recommendations for andrachne.

Warnings

Information is limited. A. cordifolia was shown to be phytotoxic in a study conducted in Pakistan.Gilani 2010

What other drugs will affect Andrachne

None well documented.

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