Anidulafungin
Generic name: Anidulafungin
Brand names: Eraxis
Dosage form: intravenous powder for injection (100 mg; 50 mg)
Drug class:
Echinocandins
Usage of Anidulafungin
Anidulafungin is an antifungal medicine that is used to treat candida (yeast) infections in the blood or the stomach in adults and children at least 1 month old.
Anidulafungin is also used to treat candida infections of the esophagus only in adults.
Anidulafungin may also be used for purposes not listed in this medication guide.
Anidulafungin side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Some side effects may occur during the injection. Tell your caregiver right away if you feel light-headed, itchy, warm, tingly, sweaty, or if you have chest tightness or trouble breathing.
Anidulafungin may cause serious side effects. Call your doctor at once if you have:
Common side effects of anidulafungin may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Anidulafungin
You should not use anidulafungin if:
Tell your doctor if you have ever had liver disease.
Tell your doctor if you are pregnant or breastfeeding.
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How to use Anidulafungin
Usual Adult Dose for Candidemia:
Initial dose: 200 mg IV as a single loading dose on Day 1Maintenance dose: 100 mg IV once a day thereafterComments:-Duration of therapy should be based on patient's clinical response.-In general, antifungal therapy should continue for at least 14 days after the last positive culture.Use: For the treatment of candidemia and the following Candida infections: intraabdominal abscess and peritonitis
Usual Adult Dose for Esophageal Candidiasis:
Initial dose: 100 mg IV as a single loading dose on Day 1Maintenance dose: 50 mg IV once a day thereafterDuration of therapy: At least 14 days and at least 7 days after resolution of symptomsComments:-Duration of therapy should be based on patient's clinical response.-Due to risk of relapse in HIV-infected patients, suppressive antifungal therapy may be considered after a course of treatment.Use: For the treatment of esophageal candidiasis
Usual Pediatric Dose for Candidemia:
1 month or older:-Initial dose: 3 mg/kg IV as a single loading dose on Day 1---Maximum dose: 200 mg/dose-Maintenance dose: 1.5 mg/kg IV once a day thereafter---Maximum dose: 100 mg/doseComments:-Overall, antifungal therapy should continue for at least 14 days after the last positive culture.Use: For the treatment of candidemia and the following Candida infections: intraabdominal abscess and peritonitis
Warnings
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
What other drugs will affect Anidulafungin
Other drugs may affect anidulafungin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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