Antihemophilic factor (recombinant) porcine sequence

Generic name: Antihemophilic Factor (recombinant) Porcine Sequence (an-tye-hee-moe-FIL-ik FAK-tor (ree-KOM-bi-nant) POR-sine SEE-kwen-se)
Drug class: Miscellaneous coagulation modifiers

Usage of Antihemophilic factor (recombinant) porcine sequence

Antihemophilic factor (AHF) recombinant porcine sequence injection is used to treat serious bleeding episodes in patients with acquired hemophilia A. The bleeding episode may be due to an injury or surgery. Antihemophilic factor recombinant porcine sequence is a manmade protein to replace the AHF produced naturally in the body to help form blood clots to stop bleeding.

Acquired Hemophilia A, also called classic hemophilia, is a condition that develops where the body does not make enough AHF. If you do not have enough AHF and you become injured, your blood will not form clots properly. You might bleed into and damage your muscles and joints. AHF injection is given to increase the levels of AHF in the blood.

This medicine is available only with your doctor's prescription.

Antihemophilic factor (recombinant) porcine sequence side effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Incidence not known

  • Chest tightness
  • confusion
  • difficulty with swallowing
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • fast heartbeat
  • hives or welts, itching, or skin rash
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • redness of the skin
  • sweating
  • unusual tiredness or weakness
  • Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

    Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

    Before taking Antihemophilic factor (recombinant) porcine sequence

    In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

    Allergies

    Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

    Pediatric

    Appropriate studies have not been performed on the relationship of age to the effects of antihemophilic factor recombinant porcine injection in the pediatric population. Safety and efficacy have not been established.

    Geriatric

    Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of antihemophilic factor recombinant porcine injection in the elderly.

    Breast Feeding

    There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

    Interactions with Medicines

    Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

    Interactions with Food/Tobacco/Alcohol

    Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

    Other Medical Problems

    The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Allergy to hamster proteins, history of or
  • Congenital (from birth) hemophilia A or
  • von Willebrand disease (a different blood clotting disorder)—Should not be used in patients with these conditions.
  • Relate drugs

    How to use Antihemophilic factor (recombinant) porcine sequence

    A doctor or other trained health professional will give you this medicine in a hospital or clinic setting. It is given through a needle placed into one of your veins. You may also be taught how to give this medicine at home.

    To prepare the medicine using 1 vial and 1 prefilled syringe:

  • Take the vial and prefilled syringe out of the refrigerator and warm them to room temperature.
  • Wipe the rubber stopper with an alcohol swab and allow them to dry.
  • Peel the lid of the vial adapter. Keep the vial on a flat surface. Hold the vial with one hand and using the other hand, connect the syringe into the vial by pushing the tip onto the luer lock (tip) in the center of the vial, turn it clockwise until secured.
  • On a flat surface, place the vial adapter over the vial and push the filter spike of the adapter into the center of the vial's rubber until the clear plastic cap snaps into the vial.
  • Slowly push down on the plunger to inject all liquid from the syringe into the vial. Swirl the bottle gently to dissolve the medicine.
  • Check the mixture to make sure it is clear and colorless. Do not use the medicine if you can see particles in it.
  • Gently unscrew the syringe from the vial by turning it counter clockwise.
  • Give the injection as directed by your doctor.
  • Dosing

    The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

    The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For injection dosage form (injection):
  • For bleeding episodes in patients with hemophilia A:
  • Adults—Dose is based on body weight and the type of bleeding episode. The dose must be determined by your doctor.
  • Children—Use and dose must be determined by your doctor.
  • Missed Dose

    Call your doctor or pharmacist for instructions.

    Storage

    Store in the refrigerator. Do not freeze.

    Keep out of the reach of children.

    Do not keep outdated medicine or medicine no longer needed.

    Ask your healthcare professional how you should dispose of any medicine you do not use.

    Use the mixture within 3 hours after it is prepared. Throw away unused mixture within 3 hours after mixing.

    Warnings

    It is very important that your doctor check you closely while you are receiving this medicine to make sure it is working properly. Blood tests are needed to check for unwanted effects.

    This medicine may cause serious allergic reactions, including anaphylaxis and angioedema, which can be life-threatening and require immediate medical attention. Tell your doctor right away if you have a large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs, rash, itching, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth after you get the injection.

    Disclaimer

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    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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