Arakoda
Generic name: Tafenoquine
Drug class:
Antimalarial quinolines
Usage of Arakoda
Arakoda is an anti-malaria medicine that interferes with the growth of parasites in the human body. Parasites that cause malaria can enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia.
Arakoda is used to prevent malaria caused by the Plasmodium vivax parasite.
Arakoda is for use in adults and children at least 16 years old who are also using another medicine called chloroquine.
Arakoda is for use in people 18 years of age and older. It is not known if Arakoda is safe and effective in children.
Arakoda side effects
Get emergency medical help if you have signs of an allergic reaction to Arakoda: hives; dizziness, difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
Common Arakoda side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Arakoda
To make sure Arakoda is safe for you, tell your doctor if:
Do not breastfeed while using tafenoquine if your baby has G6PD deficiency (or has not been tested for it). If the baby does have G6PD deficiency, you should also not breastfeed for at least 3 months after your last dose of Arakoda.
Tafenoquine may harm an unborn baby. You may need to have a negative pregnancy test before starting this treatment. Use effective birth control to prevent pregnancy while taking Arakoda, and for at least 3 months after your last dose.
Tell your doctor right away if you become pregnant.
Tell your doctor if you have ever had:
Arakoda is not approved for use by anyone younger than 16 years old.
Relate drugs
How to use Arakoda
Usual Adult Dose of Arakoda for Malaria:
300 mg orally once as a single dose.
Usual Adult Dose for Malaria Prophylaxis:
Loading dose: 200 mg orally once a day for 3 days Maintenance dose: 200 mg orally once a week Terminal prophylaxis dose: 200 mg orally once as a single dose Duration of therapy: Up to 6 months of continuous dosing Comments: -The loading dose should be administered for each of the 3 days prior to travel to malarious area. -The maintenance dose should be started 7 days after the last loading dose and should be continued while in the malarious area. -The terminal prophylaxis regimen should be administered 7 days after the last maintenance dose in the week after exit from malarious area. -The full course of therapy should be completed (including the loading dose, maintenance dose, and terminal dose). -To replace missed dose(s): ---If 1 loading dose is missed: 1 dose of 200 mg so that a total of 3 daily loading doses have been administered; the maintenance dose should be started 1 week after the last loading dose ---If 2 loading doses are missed: 2 doses of 200 mg on 2 consecutive days so that a total of 3 daily loading doses have been administered; the maintenance dose should be started 1 week after the last loading dose ---If 1 maintenance (weekly) dose is missed: 1 dose of 200 mg on any day up to the time of the next scheduled weekly dose ---If 2 maintenance (weekly) doses are missed: 1 dose of 200 mg on any day up to the time of the next scheduled weekly dose ---If at least 3 maintenance (weekly) doses are missed: 2 doses of 200 mg, administered as 200 mg once a day for 2 days up to the time of the next scheduled weekly dose ---If the terminal prophylaxis dose is missed: 1 dose of 200 mg as soon as remembered.
Usual Pediatric Dose of Arakoda for Malaria:
16 years or older: 300 mg orally once as a single dose Comments: -This drug is not indicated for the treatment of acute P vivax malaria. -This drug should be coadministered on the first or second day of appropriate antimalarial therapy for acute P vivax malaria (e.g., chloroquine). -A repeat dose is recommended if vomiting occurs within 1 hour after dosing; re-dosing should not be attempted more than once. Use: For the radical cure (prevention of relapse) of P vivax malaria in patients receiving appropriate antimalarial therapy for acute P vivax infection
Warnings
You should not use Arakoda if you have a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency. Your doctor will perform a test to make sure you do not have this condition.
Do not take Arakoda if you have a history of psychotic disorders, or you currently have psychotic symptoms including hallucinations (seeing or hearing things that are not really there), delusions (false or strange thoughts or beliefs), or disorganized thinking or behavior.
What other drugs will affect Arakoda
Other drugs may interact with tafenoquine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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