Aricept

Generic name: Donepezil (oral)
Drug class: Cholinesterase inhibitors

Usage of Aricept

Aricept improves the function of nerve cells in the brain. It works by preventing the breakdown of a chemical called acetylcholine (ah SEET il KOE leen). People with dementia usually have lower levels of this chemical, which is important for the processes of memory, thinking, and reasoning.

Aricept is used to treat mild to moderate dementia caused by Alzheimer's disease.

Aricept is not a cure for Alzheimer's disease. This condition will progress over time, even in people who take donepezil.

Aricept side effects

Get emergency medical help if you have signs of an allergic reaction to Aricept: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using Aricept and call your doctor at once if you have:

severe or ongoing vomiting;

a light-headed feeling, like you might pass out;

slow heartbeats;

seizure (convulsions);

painful or difficult urination;

new or worsening breathing problems; or

signs of stomach bleeding - severe heartburn or stomach pain, bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds.

Common Aricept side effects may include:

nausea, vomiting, diarrhea;

loss of appetite;

muscle pain;

sleep problems (insomnia); or

feeling tired;.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Aricept

You should not use Aricept if you are allergic to donepezil or certain other drugs. Tell your doctor if you are allergic to any medicines.

To make sure Aricept is safe for you, tell your doctor if you have:

a heart rhythm disorder;

a history of stomach ulcers;

an enlarged prostate or urination problems;

liver or kidney disease;

epilepsy or other seizure disorder;

trouble swallowing; or

asthma, chronic obstructive pulmonary disease (COPD), or other breathing disorder.

It is not known whether Aricept will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.

It is not known whether donepezil passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

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How to use Aricept

Usual Adult Dose for Alzheimer's Disease:

Initial dose: 5 mg orally once a day, in the evening prior to retiring Mild to moderate Alzheimer's disease: -Maintenance dose: 10 mg orally once a day, after the patient has been on an initial dose of 5 mg once a day for 4 to 6 weeks Moderate to severe Alzheimer's disease: -Maintenance dose: 23 mg orally once a day, after the patient has been on a dose of 10 mg once a day for at least 3 months Comments: A higher dose of 10 mg may or may not provide a statistically significantly greater clinical benefit than a 5 mg dose. Prescriber and patient's preference should be considered. Uses: For mild, moderate, and severe Alzheimer's type dementia

Warnings

Before taking Aricept, tell your doctor if you have a heart rhythm disorder such as "sick sinus syndrome" (slow heartbeats), an enlarged prostate, urination problems, asthma, obstructive pulmonary disease, or a seizure disorder such as epilepsy.

If you need to have any type of surgery, tell the surgeon ahead of time that you are taking Aricept.

Aricept can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

What other drugs will affect Aricept

Tell your doctor about all medicines you use, and those you start or stop using during your treatment with Aricept, especially:

NSAIDs (nonsteroidal anti-inflammatory drugs) - aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others;

This list is not complete. Other drugs may interact with donepezil, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Disclaimer

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